2 recruiting, 1 completed, 1 not yet recruiting, 1 terminated. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Recruiting 2, Not yet recruiting 1 |
| Phase 2 | 1 | Terminated 1 |
Follow 11C-PS13: new trials by email Literature Review of 11C-PS13 trials Research Report on 11C-PS13
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| [11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction [11C]PS13: [carbon-11]PS13; COX-1 PET radioligand, Sacubitril-Valsartan - Heart Failure With Reduced Ejection Fraction, Cognitive Impairment, Mild | Phase 1 | Not yet recruiting | Stony Brook University | 18 | 2026-10-01 | 2026-10-02 |
| PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) 11C-PS13 - Long COVID, Post Acute Sequelae of COVID-19 | Phase 1 | Recruiting | National Institute of Mental Health (NIMH) | 60 | 2025-06-18 | 2026-08-18 |
| PET Imaging of Cyclooxygenase in Multiple Sclerosis 11C-MC1, 11C-PS13, Ketoprofen - Multiple Sclerosis | Phase 2 | Terminated | National Institute of Mental Health (NIMH) | 7 | 2022-06-07 | 2024-06-27 |
| PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease 11C-MC1, 11C-PS13, 18f-florbetaben - Parkinson's Disease, Dementia | Phase 1 | Recruiting | National Institute of Mental Health (NIMH) | 184 | 2021-08-17 | 2026-11-02 |
| Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1) [11C]PS13 - Normal Physiology | Completed | National Institute of Mental Health (NIMH) | 52 | 2017-10-03 | 2025-08-15 |
Inflammation (3) · Cognitive Dysfunction (2) · Dementia (2) · Neuroinflammatory Diseases (2) · Alzheimer Disease (1) · Encephalitis (1) · Heart Failure (1) · Multiple Sclerosis (1) · Neurologic Manifestations (1) · Parkinson Disease (1) · Post-Acute COVID-19 Syndrome (1)
National Institute of Mental Health (NIMH) (4) · Stony Brook University (1)
United States (5)
PMID 42083927, PMID 32399622, PMID 39542698
R21AG102953 (1)