39 completed. 39 Phase 2, 13 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 39 | Completed 39 |
| Phase 1 | 13 | Completed 13 |
| Phase 3 | 1 | Completed 1 |
Follow Pneumococcal Infections: new trials by email Literature Review of Pneumococcal Infections trials Research Report on Pneumococcal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PCV24 Clinical Trial in Infants and Young Children Aged 2 Months (Minimum 6 Weeks) to 71 Months 24-Valent Pneumococcal Polysaccharide Conjugate Vaccine (RZ700), 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (Prevnar 13) - Pneumococcal Infectious Disease | Phase 2 | Completed | Reinovax Biologics Co., LTD | 480 | 2025-09-11 | 2026-07-27 |
| Clinical Trial of PCV24 in Adults Aged ≥18 Years Sinovac Low-dosage PCV24, Sinovac Middle-dosage PCV24, Sinovac High-dosage PCV24 - Pneumococcal Infectious Disease | Phase 1 / Phase 2 | Completed | Sinovac Life Sciences Co., Ltd. | 385 | 2025-06-18 | 2026-04-21 |
| A Study to Learn About How a New Pneumococcal Vaccine Works in Children PG4, 20-valent pneumococcal conjugate vaccine (20vPnC) - Pneumococcal Disease | Phase 2 | Completed | Pfizer | 225 | 2024-07-30 | 2026-03-11 |
| Phase II Clinical Trial of 24-valent Pneumococcal Polysaccharide Conjugate Vaccine Reinovax PCV24 formulation 1, Reinovax PCV24 formulation 2, Reinovax PCV24 formulation 3 - Pneumococcal Infectious Disease | Phase 2 | Completed | Reinovax Biologics Co., LTD | 992 | 2024-04-20 | 2026-08-17 |
| A Study to Learn About the Safety and Immune Response of a New Pneumococcal Vaccine in Adults Multivalent Pneumococcal Vaccine - Formulation 1, Multivalent Pneumococcal Vaccine - Formulation 2, 20-valent pneumococcal conjugate vaccine (20vPnC) - Pneumococcal Disease | Phase 1 / Phase 2 | Completed | Pfizer | 1710 | 2023-12-20 | 2026-09-25 |
| A Phase 2 Study to Learn About a Monovalent Pneumococcal Conjugate Candidate in Healthy Toddlers mPnC candidate, mPnC control - Healthy Participants | Phase 2 | Completed | Pfizer | 105 | 2023-11-08 | 2025-05-08 |
| Extension Safety and Immunogenicity Study of GPNV-001 Gamma-PN3, Pneumovax-23, Prevenar-13 - Pneumococcal Infections | Phase 1 / Phase 2 | Completed | GPN Vaccines | 60 | 2023-07-17 | 2024-12-18 |
| Safety, Tolerability, and Immunogenicity of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Healthy Infants 0.5 ml dose of 1.1 mcg VAX-24, 0.5 ml dose of PCV20, 0.5 ml dose of 2.2 mcg VAX-24 - Pneumococcal Vaccines | Phase 2 | Completed | Vaxcyte, Inc. | 802 | 2023-03-29 | 2025-09-11 |
| A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants AFX3772, Prevnar 13, Prevnar 20 - Pneumonia, Bacterial, Pneumococcal Infections | Phase 2 | Completed | GlaxoSmithKline | 388 | 2022-06-16 | 2026-10-09 |
| A Phase 1/Phase 2 Study of Polyvalent Pneumococcal Conjugate Vaccine (V116) in Adults (V116-001) V116, Pneumovax™23 - Pneumonia, Pneumococcal | Phase 1 / Phase 2 | Completed | Merck Sharp & Dohme LLC | 600 | 2019-12-06 | 2022-09-16 |
| Revaccination With PPS23 Boosted or Not by PCV13 in Splenectomised Patients. Prevenar13 (PCV13) and Pneumovax (PPS23), Placebo / Pneumovax (PPS23), Blood sample - Splenectomised Patients | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 39 | 2019-08-27 | 2026-07-01 |
| A Single Ascending Dose Study in Adults (Stage 1) and Single Ascending Dose-Finding Study (Stage 2) in Elderly Subjects With ASP3772, A Pneumococcal Vaccine ASP3772, PCV13, PPSV23 - Pneumonia, Bacterial, Healthy Volunteers | Phase 1 / Phase 2 | Completed | GlaxoSmithKline | 630 | 2019-01-24 | 2023-12-21 |
| CIRN Pneumococcal Conjugate Vaccine 1 vs. 2 Dose Priming Study PCV13 - Invasive Pneumococcal Disease, Protection Against, Streptococcus Pneumoniae Infection | Phase 2 / Phase 3 | Completed | University of British Columbia | 248 | 2018-08-23 | 2024-03-04 |
| Adjunction of Daptomycin for the Treatment of Pneumococcal Meningitis Daptomycin - Pneumococcal Meningitis | Phase 2 | Completed | Centre Hospitalier Universitaire Dijon | 112 | 2018-06-07 | 2024-10-01 |
| A Study to Evaluate the Safety and Immunogenecity of LBVE(Multivalent Pneumococcal Conjugate Vaccine) in Healthy Infants LBVE, Prevnar13 - Pneumococcal Infection | Phase 2 | Completed | LG Chem | 230 | 2018-05-25 | 2019-08-22 |
| Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine in Healthy Infants Multivalent, 13vPnC - Pneumococcal Infections | Phase 2 | Completed | Pfizer | 460 | 2018-04-16 | 2021-03-02 |
| A Trial To Evaluate A Multivalent Pneumococcal Conjugate Vaccine In Healthy Adults 50-85 Years Of Age Multivalent, Tdap, polysaccharide - Pneumococcal Infections | Phase 2 | Completed | Pfizer | 511 | 2017-10-12 | 2020-06-04 |
| Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Adults 60 Through 64 Years of Age Multivalent, Prevnar 13, PPSV23 - Pneumococcal Infections | Phase 2 | Completed | Pfizer | 444 | 2017-10-10 | 2019-12-26 |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Two Lots of V114 in Healthy Infants (V114-008) V114 Lot 1, V114 Lot 2, Prevnar 13™ - Pneumococcal Infections | Phase 2 | Completed | Merck Sharp & Dohme LLC | 1051 | 2017-03-21 | 2019-10-23 |
| Safety, Tolerability, and Immunogenicity of V114 Compared to Prevnar 13™ in PPSV23-vaccinated Healthy Adults ≥65 Years of Age (V114-007) V114, Prevnar 13™ - Pneumococcal Infections | Phase 2 | Completed | Merck Sharp & Dohme LLC | 253 | 2015-10-30 | 2019-08-14 |
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Pneumonia (5) · Pneumonia, Pneumococcal (5) · Pneumonia, Bacterial (2) · Streptococcal Infections (2) · HIV Infections (1) · Infections (1) · Leukemia (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Meningitis, Pneumococcal (1)
Bacterial Infections (39) · Bacterial Infections and Mycoses (39) · Gram-Positive Bacterial Infections (39) · Infections (38) · Streptococcal Infections (37) · Lung Diseases (9) · Respiratory Tract Diseases (9) · Respiratory Tract Infections (9) · Pneumonia (4) · Pneumonia, Bacterial (4) · Immune System Diseases (2) · Blood-Borne Infections (1) · Central Nervous System Bacterial Infections (1) · Central Nervous System Diseases (1)
13-valent pneumococcal vaccine (16) · 23-valent pneumococcal capsular polysaccharide vaccine (7) · Pneumococcal Vaccines (6) · Heptavalent Pneumococcal Conjugate Vaccine (5) · Sodium Chloride (3) · Vaccines, Combined (3) · PHiD-CV vaccine (2) · 10-valent pneumococcal conjugate vaccine (1) · Blood Specimen Collection (1) · CRM197 (non-toxic variant of diphtheria toxin) (1) · Daptomycin (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Hepatitis A Vaccines (1) · Pentavac (1) · Polysaccharides (1)
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