24 completed, 8 unknown, 7 terminated, 2 suspended. 14 Phase 2, 11 Not applicable, 7 Phase 3, 6 Phase 4, 3 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tecovirimat in Non-hospitalized Patients With Monkeypox Tecovirimat, Placebo - Monkeypox | Phase 3 | Suspended | Marina Klein | 120 | 2023-08-14 | 2026-03-04 |
| Virtual PrEP: Rendering PrEP Delivery More Efficient PrEP, mHealth Model of Care, Standard of Care - HIV Infections | Phase 4 | Terminated | Unity Health Toronto | 2 | 2023-05-01 | 2024-04-18 |
| Syphilis and HIV Point of Care Testing (POCT) in Saskatchewan Reveal Rapid TP (from MedMira) - Syphilis, HIV Infections | Not applicable | Unknown | Wellness Wheel Medical Clinic | 1650 | 2023-02-01 | 2023-05-17 |
| Optimizing the Delivery of HIV nPEP nPEP, Text Messaging Support, Nurse-Led nPEP - HIV Infections | Phase 2 | Unknown | Unity Health Toronto | 434 | 2021-11-04 | 2021-11-22 |
| Cannabinoids in PLWHIV on Effective ART TN-TC11M2 oral capsules (THC 2.5 mg/CBD 2.5 mg), TN-C200M2 oral capsules (CBD 200 mg) - HIV Infections | Phase 2 | Terminated | McGill University Health Centre/Research Institute of the McGill University Health Centre | 10 | 2021-08-20 | 2022-06-30 |
| Immunogenicity of COVID-19 Vaccination in PLWH COVID-19 Vaccine - HIV Infections | Unknown | CIHR Canadian HIV Trials Network | 500 | 2021-06-10 | 2021-10-15 | |
| Electronic Capture of Adherence Barriers for HIV Care The Opal patient portal and smartphone application combined with the I-Score patient-reported outcome measure - HIV Infections | Not applicable | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 30 | 2021-01-01 | 2021-01-08 |
| Effectiveness of a Personalized Health Profile on Specificity of Self-Management Goals My Personal Brain Health Dashboard - Chronic Disease, Goals | Not applicable | Unknown | McGill University | 420 | 2019-12-01 | 2019-11-25 |
| Estrogen, Probiotics and Vaginal Health to Prevent HIV Infection in ACB Women Estring Vaginal Ring, RepHresh Pro-B - HIV-1-infection, Bacterial Vaginoses | Phase 1 | Completed | McMaster University | 50 | 2019-11-04 | 2021-12-17 |
| Psychosocial Intervention for Older HIV+ Adults With HAND CRGT, HIV group therapy - HIV/AIDS, Aging | Not applicable | Completed | University Health Network, Toronto | 12 | 2018-08-06 | 2024-03-29 |
| Bone Health in Aging HIV Infected Women tenofovir-alafenamide-emtricitabine, tenofovir-emtricitabine - Osteoporosis, HIV | Phase 4 | Completed | University Health Network, Toronto | 34 | 2017-09-12 | 2024-12-19 |
| HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection E/C/F/TAF;, Ledipasvir-Sofosbuvir - Human Immunodeficiency Virus, Hepatitis C, Chronic | Phase 3 | Completed | Ottawa Hospital Research Institute | 25 | 2016-04-01 | 2022-11-14 |
| Improving Fibrosis Outcomes With Metformin Metformin, No metformin treatment - HIV Infection, Hepatitis C | Phase 2 | Withdrawn | Ottawa Hospital Research Institute | 2016-01-01 | 2018-04-17 | |
| Evaluation of Web-based Interventions to Support People Living With HIV in the Adoption of Health Behaviors Website A, Website B - HIV | Not applicable | Completed | Centre hospitalier de l'Université de Montréal (CHUM) | 750 | 2015-12-01 | 2022-08-25 |
| Probiotic Visbiome for Inflammation and Translocation in HIV Ι Visbiome, Placebo - HIV-1 Infection | Phase 2 | Terminated | University Health Network, Toronto | 1 | 2015-11-15 | 2018-03-01 |
| Probiotic Visbiome for Inflammation and Translocation in HIV II Visbiome, Placebo - HIV-1 Infection | Phase 2 | Unknown | University Health Network, Toronto | 36 | 2015-11-01 | 2018-04-18 |
| Evaluation of Switching From Current cART to Triumeq With Adherence Support Will Enhance HIV Control in Vulnerable Populations Switch to Triumeq, Adherence support + current ART - HIV Infections | Phase 4 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 27 | 2015-11-01 | 2020-09-03 |
| The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With Men The Hyfrecator ® 2000 Electrosurgical System, Observation Alone - Anal Dysplasia, Human Papillomavirus | Not applicable | Terminated | University Health Network, Toronto | 71 | 2015-11-01 | 2022-06-13 |
| Progesterone Supplementation for HIV-positive Pregnant Women on Anti-Retrovirals Prometrium - HIV-1 Infection | Phase 2 | Unknown | Mount Sinai Hospital, Canada | 40 | 2015-08-01 | 2015-07-30 |
| Long Term Follow-up of HPV Vaccine in HIV (CTN 236) Cervical Cancer, Human Papillomavirus Infection | Completed | University of British Columbia | 241 | 2015-06-01 | 2025-04-08 |
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HIV Infections (17) · Acquired Immunodeficiency Syndrome (6) · Hepatitis C (4) · Anus Neoplasms (2) · Osteoporosis (2) · Syphilis (2) · Acidosis, Lactic (1) · Anxiety Disorders (1) · Atherosclerosis (1) · Carcinoma, Squamous Cell (1) · Chronic Disease (1) · Cognitive Dysfunction (1) · Coinfection (1) · Condylomata Acuminata (1) · Depression (1)
Lamivudine (2) · Lopinavir (2) · emtricitabine tenofovir alafenamide (2) · ALVAC vaccine (1) · Alendronate (1) · Anti-Retroviral Agents (1) · Antioxidants (1) · Antiretroviral Therapy, Highly Active (1) · Argon Plasma Coagulation (1) · COVID-19 Vaccines (1) · Chloroquine (1) · Citalopram (1) · Dietary Supplements (1) · Dronabinol (1) · Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1)
Canada (40) · Argentina (1) · Brazil (1) · Cameroon (1) · Italy (1) · United Kingdom (1)
Julio Montaner, MD (4) · Curtis Cooper, MD (3) · Joel Singer, MD (2) · Marina Klein, MD (2) · Rupert Kaul, MD (2) · Alexandra De Pokomandy, Md (1) · Alexandra de Pokomandy, MD (1) · Aslam Anis, PhD (1) · Bill Cameron, MD (1) · Catherine Worthington, Ph.D. (1) · Cecilia Costiniuk, MD (1) · Cecilia Costiniuk, MD, MSc (1) · Curtis Cooper, MD, FRCPC (1)
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