107 completed, 8 recruiting, 4 unknown, 3 active not recruiting. 122 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 122 | Completed 107, Recruiting 8, Unknown 4, Active not recruiting 3 |
| Phase 2 | 1 | Completed 1 |
Follow Pneumococcal Infections: new trials by email Literature Review of Pneumococcal Infections trials Research Report on Pneumococcal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults PG4 Multivalent Vaccine, 20 Valent Pneumococcal Conjugate Vaccine (20vPnC) - Pneumococcal Disease | Phase 3 | Active not recruiting | Pfizer | 4701 | 2026-09-08 | 2026-11-12 |
| A Study to Evaluate 20vPnC in Healthy Chinese Infants 20vPnC, 13vPnC - Pneumococcal Diseases | Phase 3 | Recruiting | Pfizer | 1250 | 2026-07-25 | 2026-08-10 |
| Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents PG4, 20-valent pneumococcal conjugate vaccine (20vPnC) - Pneumococcal Disease | Phase 3 | Recruiting | Pfizer | 1200 | 2026-06-15 | 2026-10-26 |
| A Study to Learn About How a New Pneumococcal Vaccine Works in Infants. PG4, 20-valent pneumococcal conjugate vaccine (20vPnC) - Pneumococcal Disease | Phase 3 | Recruiting | Pfizer | 3230 | 2026-05-29 | 2026-10-20 |
| A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants PG4, 20-valent pneumococcal conjugate vaccine (20vPnC) - Pneumococcal Disease | Phase 3 | Recruiting | Pfizer | 2400 | 2026-05-04 | 2026-11-06 |
| Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Prior Pneumococcal Vaccination 31-valent pneumococcal conjugate vaccine, PCV20 - Pneumococcal Disease | Phase 3 | Completed | Vaxcyte, Inc. | 752 | 2026-02-09 | 2026-11-13 |
| Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age PCV21 vaccine, 20vPCV licensed vaccine - Pneumococcal Immunization, Healthy Volunteers | Phase 3 | Recruiting | Sanofi | 2195 | 2026-01-20 | 2026-10-05 |
| A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age 31-valent pneumococcal conjugate vaccine, Seasonal Influenza Vaccine (SIV) (Flublok), Placebo - Pneumococcal Disease | Phase 3 | Completed | Vaxcyte, Inc. | 1390 | 2026-01-12 | 2026-11-13 |
| Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Immunobridging to Adults 18-49 31 valent pneumococcal conjugate vaccine, PCV20, PCV21 - Pneumococcal Disease | Phase 3 | Completed | Vaxcyte, Inc. | 4049 | 2025-12-01 | 2026-10-16 |
| A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infants Aged 2 Months (Minimum 6 Weeks) PCV13i, Prevnar 13 - Pneumococcal Infections, Streptococcal Infections | Phase 3 | Active not recruiting | CanSino Biologics Inc. | 600 | 2025-11-14 | 2026-08-05 |
| Study of the Safety and Immunogenicity of Catch-up Vaccination With a 21-valent Pneumococcal Conjugate Vaccine (PCV21) in Healthy Infants, Toddlers, Children, and Adolescents PCV21, 20vPCV - Pneumococcal Infections | Phase 3 | Active not recruiting | Sanofi Pasteur, a Sanofi Company | 1268 | 2025-02-28 | 2025-10-06 |
| A Phase 3 Study to Evaluate the Immunogenicity and Safety of Minhai's PCV13-DT/TT Vaccine As Compared to Pfizer's PCV13 Vaccine pneumococcal disease prevention - Pneumococcal Vaccines, Pneumococcal Infections | Phase 3 | Recruiting | Beijing Minhai Biotechnology Co., Ltd | 500 | 2024-11-01 | 2025-03-24 |
| Clinical Trial of 13-Valent Pneumococcal Conjugate Vaccine Sinovac PCV13, Prevnar® - Pneumococcal Infectious Disease | Phase 3 | Recruiting | Sinovac Life Sciences Co., Ltd. | 3080 | 2024-10-23 | 2026-01-28 |
| A Clinical Study of the V116 Vaccine for Children and Teenagers (V116-013) V116, PPSV23 - Pneumococcal Infection | Phase 3 | Completed | Merck Sharp & Dohme LLC | 882 | 2024-01-18 | 2026-03-11 |
| A Phase 3 Study to Evaluate the Immunogenicity and Safety of Walvax's PCV13-TT as Compared to Pfizer's PCV13 Walvax PCV13-TT, Pfizer PCV13 - Pneumococcal Disease, Invasive | Phase 3 | Unknown | Walvax Biotechnology Co., Ltd. | 630 | 2023-11-23 | 2024-07-03 |
| A Clinical Trial to Evaluate the Immunogenicity and Safety of the 23-valent Pneumococcal Polysaccharide Vaccine in Healthy People 23-valent pneumococcal polysaccharide vaccine, control pneumococcal polysaccharide vaccine - Pneumococcal Disease | Phase 3 | Recruiting | Aimei Vacin BioPharm (Zhejiang) Co., Ltd. | 1920 | 2023-09-08 | 2023-09-21 |
| A Study to Learn About the Safety and Immune Response of 20vPnC in Adults in India. 20-valent pneumococcal conjugate vaccine - Pneumococcal Disease | Phase 3 | Completed | Pfizer | 405 | 2023-08-16 | 2024-10-24 |
| Safety and Immunogenicity of V116 in Adults With Increased Risk for Pneumococcal Disease (V116-008) V116, Placebo, PCV15 - Pneumococcal Infection | Phase 3 | Completed | Merck Sharp & Dohme LLC | 518 | 2023-02-13 | 2026-03-03 |
| Safety and Immunogenicity of V116 in Vaccine-naïve Japanese Older Adults (V116-009, STRIDE-9) V116, PPSV23 - Pneumococcal Disease | Phase 3 | Completed | Merck Sharp & Dohme LLC | 450 | 2023-01-10 | 2024-10-02 |
| Safety and Immunogenicity of V116 in Pneumococcal Vaccine-naïve Adults 50 Years of Age or Older (V116-010, STRIDE-10) V116, PPSV23 - Pneumococcal Disease | Phase 3 | Completed | Merck Sharp & Dohme LLC | 1484 | 2022-11-07 | 2026-03-02 |
Showing 20 of 122. Sign in to see all of them.
Streptococcal Infections (23) · Pneumonia, Pneumococcal (8) · Otitis Media (4) · Pneumonia (4) · Acquired Immunodeficiency Syndrome (3) · Diphtheria (3) · HIV Infections (3) · Tetanus (3) · Bacterial Infections (2) · Fever (2) · Meningococcal Infections (2) · Otitis Media with Effusion (2) · Poliomyelitis (2) · Rotavirus Infections (2)
Bacterial Infections and Mycoses (122) · Infections (122) · Gram-Positive Bacterial Infections (121) · Bacterial Infections (120) · Streptococcal Infections (99) · Respiratory Tract Diseases (16) · Respiratory Tract Infections (15) · Lung Diseases (13) · Virus Diseases (11) · RNA Virus Infections (10) · Pneumonia (9) · Pneumonia, Bacterial (8) · Blood-Borne Infections (5) · Communicable Diseases (5)
13-valent pneumococcal vaccine (23) · 23-valent pneumococcal capsular polysaccharide vaccine (16) · Heptavalent Pneumococcal Conjugate Vaccine (10) · PHiD-CV vaccine (10) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (10) · Pneumococcal Vaccines (7) · RIX4414 vaccine (6) · 2,4,5,4'-tetrachlorodiphenylsulfoxide (5) · Hiberix (5) · Sodium Chloride (5) · Chickenpox Vaccine (3) · Pentetic Acid (3) · Tritanrix-HepB vaccine (3) · Acetaminophen (2) · Blood Specimen Collection (2)
Merck Sharp & Dohme LLC (33) · Pfizer (31) · GlaxoSmithKline (25) · Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd (3) · SK Chemicals Co., Ltd. (3) · Vaxcyte, Inc. (3) · Wyeth is now a wholly owned subsidiary of Pfizer (3) · CanSino Biologics Inc. (2) · PATH (2) · Sanofi Pasteur, a Sanofi Company (2) · Aimei Vacin BioPharm (Zhejiang) Co., Ltd. (1) · Beijing Minhai Biotechnology Co., Ltd (1) · Finnish Institute for Health and Welfare (1) · Fosun Adgenvax Biopharmaceutical Co.,Ltd. (1) · Menzies School of Health Research (1)
United States (42) · Poland (17) · Spain (13) · Australia (12) · Finland (12) · Canada (11) · China (11) · Japan (11) · Thailand (11) · South Korea (10) · Sweden (10) · Taiwan (10) · Germany (9) · Puerto Rico (9) · France (8)
Amanda J Leach, PhD (2) · Du Lin, Master (2) · Edward K Mulholland, DM (2) · Jonathan R Carapetis, PhD (2) · Peter S Morris, PhD (2) · Ross M Andrews, PhD (2) · Andrew J Pollard, BSc MBBS PhD MRCP FRCPCH (1) · Ed Clarke (1)
PMID 25008901, PMID 36211411, PMID 36368038, PMID 37846456, PMID 41187484, PMID 11172176, PMID 14557958, PMID 19325447, PMID 19325451, PMID 19325452, PMID 19584345, PMID 20088694, PMID 20823436, PMID 20980796, PMID 21695210, PMID 21807056, PMID 21813135, PMID 21860256, PMID 23658394, PMID 23804191, PMID 24120678, PMID 24356787, PMID 24447437, PMID 24921688, PMID 25278086, PMID 25329446, PMID 25355940, PMID 25395187, PMID 25499011, PMID 25888646, PMID 26020101, PMID 26506438, PMID 26529076, PMID 27149114, PMID 27254028, PMID 27258647, PMID 27422342, PMID 28079828, PMID 28087146, PMID 28425818, PMID 28987445, PMID 30215583, PMID 30603376, PMID 31364010, PMID 31626050, PMID 31995183, PMID 32035706, PMID 32966176, PMID 33245004, PMID 33516293
2018 (13), 2019 (7), 2017 (3), 2014 (2), 2025 (2), 2009 (1), 2015 (1), 2023 (1)