7 completed, 2 not yet recruiting, 2 terminated, 1 unknown. 7 Not applicable, 3 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
Follow PMS: new trials by email Literature Review of PMS trials Research Report on PMS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Impact of Psychoeducation and Sleep-informed Workshop Targeting Sleep Concerns in Women and Individuals With Premenstrual Dysphoric Disorder Psychoeducation and Sleep-Informed Workshop - Sleep Disturbances, PMDD | Not applicable | Not yet recruiting | St. Joseph's Healthcare Hamilton | 72 | 2026-06-01 | 2026-04-28 |
| Microdosing LSD in Women With Premenstrual Disorders LSD 10 μg every Day, LSD 10 μg every other day, Placebo - PMS, PMDD | Not applicable | Not yet recruiting | Friederike Holze | 150 | 2025-10-01 | 2025-09-23 |
| A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome PMS Capsule, Capsule Placebo, PMS Gummy - PMS, Menstrual Cramp | Not applicable | Completed | Semaine Health | 176 | 2024-09-04 | 2025-01-08 |
| The Effect of Laughter Therapy On The Food Craving Assigned Interventions - PMS, LAUGHTER | Not applicable | Unknown | Sinop University | 90 | 2023-11-20 | 2023-12-26 |
| An Investigation of Premama Balance and Its Effects on Hormonal Imbalances PreMama Balance, Placebo Drink - PMS, Menstrual Discomfort | Not applicable | Withdrawn | Premama Inc. | 2022-12-30 | 2024-04-03 | |
| Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25 Cramp Bites by Aunt Flo's Kitchen - Dysmenorrhea Primary, Dysmenorrhea | Phase 2 / Phase 3 | Completed | Cornell University | 12 | 2022-07-21 | 2024-04-12 |
| Study to Evaluate Your Super's Moon Balance and Its Impact on Premenstrual Syndrome Moon Balance - PMS, Menstrual Discomfort | Not applicable | Completed | Your Super, INC. | 38 | 2022-02-15 | 2022-06-21 |
| Study to Evaluate the Efficacy of Elix's Cycle Balance and Its Impact on PMS and Menstrual Symptoms Elix Cycle Balance - PMS, Menstrual Pain | Not applicable | Completed | Zenchi, Inc. | 68 | 2022-01-05 | 2025-01-01 |
| Prevalence of Lidocaine Ineffectiveness in Adults With and Without ADHD Lidocaine gel - ADHD, PMS | Early Phase 1 | Completed | PhenoSolve, LLC | 90 | 2019-08-14 | 2022-10-06 |
| A Study to Evaluate the Effects of RCN3028 on Moderate to Severe Vasomotor Symptoms in Women I placebo capsule, II RDC 0.3mg capsule, III RDC 0.6mg capsule - PMS, Hot Flashes | Phase 2 | Completed | Yung Shin Pharm. Ind. Co., Ltd. | 58 | 2014-03-19 | 2022-02-14 |
| Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study escitalopram, placebo - PMS | Phase 4 | Terminated | University of Pennsylvania | 11 | 2008-02-01 | 2014-06-06 |
| Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives Ethinyl Estradiol/Drospirenone, Placebo, CDB 2914 - Premenstrual Syndrome, PMS | Phase 2 | Terminated | National Institute of Mental Health (NIMH) | 5 | 2004-07-01 | 2017-08-25 |
| Dutasteride to Treat Women With Menstrually Related Mood Disorders Dutasteride, Placebo oral capsule - Premenstrual Syndrome, PMS | Phase 1 | Completed | National Institute of Mental Health (NIMH) | 34 | 2004-03-31 | 2019-12-17 |
Dysmenorrhea (5) · Premenstrual Syndrome (5) · Depression (2) · Menstruation Disturbances (2) · Premenstrual Dysphoric Disorder (2) · Attention Deficit Disorder with Hyperactivity (1) · Constipation (1) · Diarrhea (1) · Endocrine System Diseases (1) · Fatigue (1) · Feeding Behavior (1) · Headache (1) · Hot Flashes (1) · Laughter (1) · Migraine Disorders (1)
Pathological Conditions, Signs and Symptoms (10) · Pathologic Processes (9) · Menstruation Disturbances (7) · Signs and Symptoms (6) · Neurologic Manifestations (5) · Pain (5) · Pelvic Pain (5) · Mental Disorders (4) · Behavior (3) · Nervous System Diseases (3) · Behavioral Symptoms (2) · Depressive Disorder (2) · Mood Disorders (2) · Adnexal Diseases (1) · Attention Deficit and Disruptive Behavior Disorders (1)
Dutasteride (1) · Escitalopram (1) · Lysergic Acid Diethylamide (1) · Methods (1) · Spectrometry, Fluorescence (1) · drospirenone and ethinyl estradiol combination (1) · ulipristal (1)
National Institute of Mental Health (NIMH) (2) · Cornell University (1) · Friederike Holze (1) · PhenoSolve, LLC (1) · Premama Inc. (1) · Semaine Health (1) · Sinop University (1) · St. Joseph's Healthcare Hamilton (1) · University of Pennsylvania (1) · Your Super, INC. (1) · Yung Shin Pharm. Ind. Co., Ltd. (1) · Zenchi, Inc. (1)
United States (8) · Canada (1) · Switzerland (1) · Taiwan (1) · Turkey (Türkiye) (1)
Pedro E Martinez, M.D. (2) · Susanne Mitschke (2) · Ellen Freeman (1) · Michael Segal, MD PhD (1) · Susanne Mitschke, MSc (1)