12 completed. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 12 |
Follow Pleural Diseases: new trials by email Literature Review of Pleural Diseases trials Research Report on Pleural Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Thoracoscopic Talc Pleurodesis Versus Bleomycin -Tranxemic Acid Mixture Injection in Chest Tube in Malignant Pleural Effusion thoracoscope - Malignant Pleural Effusions (Mpe)- Pleurodesis, Pleurodesis | Phase 4 | Completed | Mohamed Sabry | 60 | 2024-09-01 | 2024-12-20 |
| Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis Cathflo Activase, Talc Slurry Pleurodesis - Pleural Effusion | Phase 4 | Completed | Memorial Healthcare System | 27 | 2021-06-15 | 2025-06-08 |
| Management of Pleural Space Infections Intrapleural Medications, Surgery, Pleural Sampling - Empyema, Pleural, Parapneumonic Effusion | Phase 4 | Completed | Swedish Medical Center | 26 | 2019-04-01 | 2022-11-22 |
| Diaphragmatic Resection And Gynecological Ovarian Neoplasm thoracic Drain Tube 24 Fr. - Ovarian Cancer | Phase 4 | Completed | Catholic University of the Sacred Heart | 88 | 2018-03-20 | 2020-05-22 |
| Fibrinolysis Compared to Thoracoscopy for Pleural Infection tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase), Medical Thoracoscopy - Pleural Infection, Empyema | Phase 4 | Completed | Tulane University | 32 | 2017-11-01 | 2021-02-04 |
| Fibrinolytic Therapy Versus Medical Thoracoscopy Chest thoracoscopy, Chest fibrinolytic therapy, tPA - Pleural Diseases | Phase 4 | Completed | University of Florida | 5 | 2017-09-14 | 2024-02-20 |
| Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy Cefazolin, saline - Pleural Effusion, Pleurisy | Phase 4 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 100 | 2015-01-01 | 2017-01-18 |
| Safety Profile of Iodopovidone as an Agent for Pleurodesis in Malignant Pleural Effusion pleurodesis - Pleural Effusion, Malignant | Phase 4 | Completed | Grupo de Pesquisa em Pleura e Oncologia Toracica | 60 | 2010-01-01 | 2014-05-13 |
| Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter Standard Drainage Instructions, Aggressive Drainage Instructions - Pleural Effusion, Malignant | Phase 4 | Completed | Duke University | 150 | 2009-08-01 | 2013-12-30 |
| Talc Pleurodesis in Patients With Recurrent Malignant Pleural Effusion Videothoracoscopic talc poudrage (VT)., Talc slurry through a chest tube (DT). - Recurrent Malignant Pleural Effusion. | Phase 4 | Completed | University of Sao Paulo | 60 | 2005-01-01 | 2008-11-11 |
| Non-small Cell Lung Cancer Registry zoledronic acid - Non-Small-Cell Lung Cancer, Pleural Effusion, Malignant | Phase 4 | Completed | Novartis Pharmaceuticals | 300 | 2004-11-01 | 2009-11-23 |
| Efficacy and Security of Intrapleurally Alteplase vs Urokinase for the Treatment of Complicated Parapneumonic Effusion and Empyema Intrapleurally Alteplase vs Intrapleurally Urokinase - Empyema, Pleural, Pleural Effusion | Phase 4 | Completed | Hospital Universitari Vall d'Hebron Research Institute | 204 | 2003-12-01 | 2011-07-18 |
Pleural Effusion (5) · Pleural Effusion, Malignant (5) · Empyema (2) · Empyema, Pleural (2) · Carcinoma, Non-Small-Cell Lung (1) · Lung Neoplasms (1) · Ovarian Neoplasms (1) · Pleurisy (1)
Respiratory Tract Diseases (12) · Neoplasms (6) · Neoplasms by Site (6) · Pleural Neoplasms (5) · Respiratory Tract Neoplasms (5) · Thoracic Neoplasms (5) · Infections (4) · Inflammation (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Pleural Effusion (4) · Suppuration (4) · Respiratory Tract Infections (3) · Empyema (2)
Tissue Plasminogen Activator (3) · Cefazolin (1) · Clindamycin (1) · Deoxyribonucleases (1) · Pleurodesis (1) · Quality of Life (1) · Sodium Chloride (1) · Surgical Procedures, Operative (1) · Thoracoscopes (1) · Thoracoscopy (1) · Zoledronic Acid (1) · dornase alfa (1)
Catholic University of the Sacred Heart (1) · Duke University (1) · Grupo de Pesquisa em Pleura e Oncologia Toracica (1) · Hospital Universitari Vall d'Hebron Research Institute (1) · Memorial Healthcare System (1) · Mohamed Sabry (1) · Novartis Pharmaceuticals (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Swedish Medical Center (1) · Tulane University (1) · University of Florida (1) · University of Sao Paulo (1)
United States (6) · Brazil (2) · Egypt (1) · India (1) · Italy (1) · Spain (1)
Fayez Kheir, MD, MSc (1) · Hiren Mehta, MD (1) · Jed Gorden, MD (1) · L. Lacerna, MD (1) · Mark Block, MD (1) · Momen Wahidi, MD, MBA (1) · Ricardo M Terra, MD, PhD (1) · Ricardo M. Terra, MD (1) · Stefano Cianci, M.D. (1)