15 recruiting, 8 completed, 4 not yet recruiting, 4 unknown. 35 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 35 | Recruiting 15, Completed 8, Not yet recruiting 4, Unknown 4, Active not recruiting 3, Enrolling by invitation 1 |
Follow Perimenopause: new trials by email Literature Review of Perimenopause trials Research Report on Perimenopause
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Structured Health Information-Seeking Training on Cyberchondria and E-Health Literacy in Menopausal Women: A Randomized Controlled Trial Video-Based Health Information-Seeking Education, Pecha Kucha-Based Health Information-Seeking Education - Perimenopause, Postmenopause | Not applicable | Not yet recruiting | Istanbul University | 60 | 2027-01-24 | 2026-09-22 |
| No Time to Pause: Physical Activity to Improve Health of Midlife Hispanic Women Physical activity intervention - Elevated Blood Pressure, Perimenopause | Not applicable | Not yet recruiting | The University of Texas Medical Branch, Galveston | 40 | 2027-01-20 | 2025-12-08 |
| Evaluation of the Effects of Lifestyle Medicine and Mindfulness-based Group Medical Visits on Stress, Microbiome, and Quality of Life in Women Experiencing Perimenopause and Menopause Navigating Menopause with a Mindfulness-Based Group Medical Visit - Perimenopause, Menopause | Not applicable | Not yet recruiting | Ohio State University | 40 | 2027-01-01 | 2026-10-16 |
| Effects of a Dietary Supplement in Women With Late Perimenopause or Early Postmenopause Plant Extract-Based Dietary Supplement, Placebo - Perimenopause, Postmenopause | Not applicable | Recruiting | University of Alicante | 120 | 2026-11-01 | 2026-10-13 |
| Hop Extract Versus Soy Isoflavone Extract for Menopausal Symptoms (HOPES) Full Spectrum hop extract (MENODUO FullSpectrum), Soy isoflavone extract - Menopause, Perimenopause | Not applicable | Recruiting | Menoclinica by Palacios | 120 | 2026-10-26 | 2026-11-05 |
| Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause transcutaneous auricular neurostimulation (tAN) - Perimenopause, PMDD | Not applicable | Enrolling by invitation | Texas Christian University | 20 | 2026-10-22 | 2026-10-23 |
| Effect of Lifestyle Intervention on Menopausal Symptoms, Sleep Quality, and Anxiety in Peri- and Postmenopausal Women Structured Lifestyle Education, Standard Care (in control arm) - Perimenopause, Postmenopause | Not applicable | Recruiting | Konya Beyhekim Training and Research Hospital | 100 | 2026-10-15 | 2026-10-16 |
| Cuidar-ME, a Web-based Psychological Intervention for (Peri)Menopausal Women: A Pilot Randomized Controlled Trial Cuidar-ME - Menopause, Perimenopause | Not applicable | Active not recruiting | University of Coimbra | 150 | 2026-09-01 | 2026-10-01 |
| Amygdala Insula Retraining in the Management of Perimenopause Symptoms Amygdala and Insula Retraining (AIR) - Perimenopause, Menopausal Complaints | Not applicable | Recruiting | Chronic Conditions Research Fund | 160 | 2026-07-15 | 2026-06-29 |
| Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being Functional Snacks, Placebo Snacks - Perimenopause, Perimenopause-Related Depression | Not applicable | Recruiting | King's College London | 20 | 2026-04-24 | 2026-05-20 |
| 12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being. Placebo, Multivitamin/mineral supplement - Perimenopause, Perimenopausal Women | Not applicable | Active not recruiting | Northumbria University | 58 | 2026-04-07 | 2026-08-05 |
| Exercise in Perimenopause to Improve Cognitive Health Progressive Resistance Training, Balance, Flexibility, and Tone Exercises - Perimenopause, Subjective Cognitive Complaints | Not applicable | Recruiting | University of British Columbia | 50 | 2026-03-30 | 2026-10-20 |
| Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women Multi-acupoint low-level laser therapy, Sham Laser irradiation, Diet and exercise guidance - Menopause, Perimenopause | Not applicable | Recruiting | Chang Gung Memorial Hospital | 40 | 2026-03-16 | 2026-03-20 |
| Shatavari Root Extract for Perimenopausal Symptoms Shatavari (Asparagus racemosus) Root Extract, Placebo Capsule - Perimenopause, Women Health | Not applicable | Not yet recruiting | SF Research Institute, Inc. | 60 | 2026-03-11 | 2026-03-03 |
| A Study to Evaluate the Efficacy of a Postbiotic Supplement on Menopausal Symptoms in Premenopausal Women Supplement, Placebo - Perimenopause, Menopausal Symptoms | Not applicable | Completed | Able Biolabs, LLC | 80 | 2026-03-04 | 2026-06-01 |
| The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health. Sarmentosin - L- theanine, Resistance Training, Placebo Supplement - Perimenopause, Menopause | Not applicable | Recruiting | Leeds Beckett University | 72 | 2026-03-01 | 2026-03-27 |
| Time-Restricted Eating in Combination With a Low Glycaemic Index Diet on Cognitive Function, Biological Ageing and Metabolic Health in Perimenopause and Menopause. Time-Restricted Low-Glycaemic Index Diet - Late-perimenopause, Menopause | Not applicable | Recruiting | University of Nicosia | 72 | 2026-01-17 | 2026-01-30 |
| Impact of Funcional Exercise and Supplementation in Perimenopausal Women's Health Exercise + nutritional supplement, Exercise + placebo supplement - Perimenopause, Aging | Not applicable | Recruiting | University of Valencia | 90 | 2025-12-15 | 2025-12-22 |
| 12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being Placebo, Magnesium hydroxide 375mg - Perimenopause, Perimenopausal Women | Not applicable | Active not recruiting | Northumbria University | 58 | 2025-12-09 | 2026-08-05 |
| Probiotic Intake and Perimenopausal Psychological Assessments Multi-strain probiotic, Placebo - Emotional Processing and Cognitive Function in Perimenopausal Women Experiencing Cognitive Perturbations, Perimenopause | Not applicable | Recruiting | University of Oxford | 106 | 2025-11-12 | 2026-05-15 |
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Anxiety Disorders (4) · Motor Activity (4) · Depression (3) · Hot Flashes (2) · Hypertension (2) · Intermittent Fasting (2) · Psychological Well-Being (2) · Sleep Initiation and Maintenance Disorders (2) · Cardiovascular Diseases (1) · Fatigue (1) · Insulin Resistance (1) · Obesity (1) · Overweight (1) · Premenstrual Dysphoric Disorder (1)
Behavior (8) · Mental Disorders (6) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (4) · Behavioral Symptoms (3) · Cardiovascular Diseases (2) · Dyssomnias (2) · Fasting (2) · Feeding Behavior (2) · Nervous System Diseases (2) · Nutritional and Metabolic Diseases (2) · Personal Satisfaction (2) · Sleep Disorders, Intrinsic (2) · Sleep Wake Disorders (2) · Vascular Diseases (2)
Dietary Supplements (2) · Anti-Inflammatory Agents, Non-Steroidal (1) · Cognitive Behavioral Therapy (1) · Contraceptives, Oral (1) · Creatine (1) · Diet (1) · Diet, Mediterranean (1) · Escitalopram (1) · Exercise (1) · Geritol (1) · Magnesium Hydroxide (1) · Orlistat (1) · Pliability (1) · Resistance Training (1) · Soybean Proteins (1)
Northumbria University (2) · AGUNCO Obstetrics and Gynecology Centre (1) · Able Biolabs, LLC (1) · American University of Beirut Medical Center (1) · Chang Gung Memorial Hospital (1) · Chronic Conditions Research Fund (1) · Dr. Nazanin Alavi (1) · Guangdong Provincial Hospital of Traditional Chinese Medicine (1) · Hologram Sciences (1) · Istanbul University (1) · King's College London (1) · Konya Beyhekim Training and Research Hospital (1) · Leeds Beckett University (1) · Mayo Clinic (1) · Menoclinica by Palacios (1)
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Abbi Lane, PhD (1) · Abbie Smith-Ryan, PhD (1) · Ana Rodriguez-Mateos, PhD (1) · Elena Philippou, PhD (1) · Elizabeth Lorenzo, PhD, RN (1) · Nadia T Dandan, PsyD (1) · Naima Covassin, Ph.D. (1) · Nazanin Alavi, MD, FRCPC (1) · Phil Burnet, Professor (1) · Sarah E Hill, PhD (1) · Sergej Ostojic, MD, PhD (1) · Sheryl M Green, PhD, CPsych (1)
PMID 12914663, PMID 26425364, PMID 30003102, PMID 31155270, PMID 31473867, PMID 33095879, PMID 34816248, PMID 35382992, PMID 39138739, PMID 40013047, PMID 40384525, PMID 40854087
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