10 completed, 2 unknown. 12 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 10, Unknown 2 |
| Phase 3 | 3 | Completed 3 |
Follow PCOS: new trials by email Literature Review of PCOS trials Research Report on PCOS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome Vitamin D3, Placebo Oral Tablet - PCOS, Vitamin D | Phase 2 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 66 | 2023-09-21 | 2024-08-12 |
| Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25 Cramp Bites by Aunt Flo's Kitchen - Dysmenorrhea Primary, Dysmenorrhea | Phase 2 / Phase 3 | Completed | Cornell University | 12 | 2022-07-21 | 2024-04-12 |
| Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome Resveratrol (1000mg twice a day), Myoinositol 1000mg (Twice a day), Metformin (500 mg Twice a day), Pioglitazone (15 mg Twice a day) - PCOS | Phase 2 | Completed | Khyber Medical University Peshawar | 88 | 2021-05-03 | 2021-09-13 |
| Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome Metformin (1000 mg daily), Pioglitazone (30 mg daily), Acetyl-L-carnitine (3 gm daily), Metformin, pioglitazone and placebo - PCOS | Phase 2 | Completed | Khyber Medical University Peshawar | 147 | 2019-10-15 | 2020-02-05 |
| The Effect of Ibuprofen on Women With PCOS. Ibuprofen - PCOS, Hyperandrogenism | Phase 2 | Unknown | Poznan University of Medical Sciences | 20 | 2019-09-01 | 2020-07-24 |
| Treating PCOS With Semaglutide vs Active Lifestyle Intervention Semaglutide 3mg and 7mg [Rybelsus], Weight loss diet - PCOS, Adolescent Obesity | Phase 2 / Phase 3 | Completed | University of Colorado, Denver | 60 | 2019-05-03 | 2025-11-25 |
| N-Acetylcysteine and L-carnitine in Pcos N-Acetylcysteine, L-carnitine - PCOS | Phase 2 | Completed | Zagazig University | 164 | 2017-01-01 | 2018-09-18 |
| L-carnitine and Metformin in Obese PCOS Women. L-carnitine and Metformin, placebo - PCOS | Phase 2 | Completed | Zagazig University | 280 | 2017-01-01 | 2018-05-02 |
| A Clinical and Biological Research of Combined Chinese and Western Medicine in the Treatment of PCOS Dingkundan, Dingkundan & Diane-35, Diane-35 - PCOS | Phase 2 | Unknown | Aijun Sun | 315 | 2016-10-01 | 2018-02-05 |
| Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents Metformin and Spironolactone - PCOS | Phase 2 / Phase 3 | Completed | Children's Mercy Hospital Kansas City | 12 | 2016-07-02 | 2021-02-23 |
| Correction of Vitamin D Deficiency and Its Effect on Ovulation Induction in Women With PCOS (VIDEO): A Feasibility RCT Vitamin D, Ovulatory Agent - PCOS | Phase 2 | Completed | Ain Shams University | 300 | 2016-02-01 | 2018-11-16 |
| Cavitation Ultrasound in Treatment of Patients With PCOS Cavitation US, Metformin, Cavitation US + Metformin - PCOS | Phase 2 | Completed | Ain Shams University | 198 | 2011-06-01 | 2017-04-07 |
Polycystic Ovary Syndrome (4) · Dysmenorrhea (1) · Hyperandrogenism (1) · Inflammation (1) · Insulin Resistance (1) · Menstruation Disturbances (1) · Muscle Cramp (1) · Non-alcoholic Fatty Liver Disease (1) · Ovarian Cysts (1) · Pediatric Obesity (1) · Premenstrual Dysphoric Disorder (1) · Premenstrual Syndrome (1)
Endocrine System Diseases (5) · Female Urogenital Diseases (5) · Female Urogenital Diseases and Pregnancy Complications (5) · Gonadal Disorders (5) · Urogenital Diseases (5) · Adnexal Diseases (4) · Cysts (4) · Genital Diseases (4) · Genital Diseases, Female (4) · Neoplasms (4) · Ovarian Diseases (4) · Ovarian Cysts (3) · Pathological Conditions, Signs and Symptoms (3) · Pathologic Processes (2) · Signs and Symptoms (2)
Metformin (5) · Carnitine (2) · Pioglitazone (2) · Acetylcarnitine (1) · Acetylcysteine (1) · Cholecalciferol (1) · Clomiphene (1) · Cyproterone acetate, ethinyl estradiol drug combination (1) · Diet, Reducing (1) · Ibuprofen (1) · Inositol (1) · Ovulation Induction (1) · Resveratrol (1) · Spironolactone (1) · Vitamin D (1)
Ain Shams University (2) · Khyber Medical University Peshawar (2) · Zagazig University (2) · Aijun Sun (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Children's Mercy Hospital Kansas City (1) · Cornell University (1) · Poznan University of Medical Sciences (1) · University of Colorado, Denver (1)
Egypt (4) · United States (3) · Pakistan (2) · Bangladesh (1) · China (1) · Poland (1)
Mohsin Shah, PhD (2) · Ahmed K. Makled, MD (1) · Aijun Sun, MD (1) · Beata Banaszewska (1) · Melanie Cree-Green, MD, PhD (1) · Mohamed I. Ellaithy, MD (1) · Mostafa I. Ibrahem, M.D. (1) · Nilufar Yasmin, MD (1) · Tania Burgert, MD (1)
PMID 31236888, PMID 31273783, PMID 32915426, PMID 34047916, PMID 34873082, PMID 36169918, PMID 42014131
R01DK120612 (1)