6 completed, 2 unknown. 8 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 6, Unknown 2 |
| Phase 2 | 3 | Completed 3 |
Follow PCOS: new trials by email Literature Review of PCOS trials Research Report on PCOS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25 Cramp Bites by Aunt Flo's Kitchen - Dysmenorrhea Primary, Dysmenorrhea | Phase 2 / Phase 3 | Completed | Cornell University | 12 | 2022-07-21 | 2024-04-12 |
| Treating PCOS With Semaglutide vs Active Lifestyle Intervention Semaglutide 3mg and 7mg [Rybelsus], Weight loss diet - PCOS, Adolescent Obesity | Phase 2 / Phase 3 | Completed | University of Colorado, Denver | 60 | 2019-05-03 | 2025-11-25 |
| Myo-inositol as Pretreatment in Hyperandrogenic PCOS Patients Myo-inositol, Folic Acid - PCOS, Female Infertility | Phase 3 | Unknown | Universitair Ziekenhuis Brussel | 134 | 2018-09-01 | 2018-12-06 |
| Comparing the Effects of Oral Contraceptive Pills Versus Metformin OCP + Metformin, OCP + Placebo, Metformin + Placebo - PCOS | Phase 3 | Completed | Anuja Dokras | 240 | 2018-01-15 | 2025-11-05 |
| Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents Metformin and Spironolactone - PCOS | Phase 2 / Phase 3 | Completed | Children's Mercy Hospital Kansas City | 12 | 2016-07-02 | 2021-02-23 |
| Effect of Bromocriptine on Insulin Resistance in Polycystic Ovarian Syndrome - A Pilot Study Bromocriptine - PCOS, Insulin Resistance | Phase 3 | Unknown | IWK Health Centre | 60 | 2014-07-01 | 2014-05-08 |
| Use of Degarelix in Controlled Ovarian Hyperstimulation (COH) Protocol for Women With PoliCystic Ovarian Syndrome (PCOS) degarelix (long acting GnRH antagonist), cetrorelix 0.25mg - PCOS, OHSS | Phase 3 | Completed | Centre for Endocrinology and Reproductive Medicine, Italy | 80 | 2012-11-01 | 2016-04-27 |
| Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS) Dexamethasone, recombinant human chorionic gonadotropin (r-hCG) - PCOS | Phase 3 | Completed | University of California, San Diego | 24 | 2011-08-01 | 2019-04-30 |
Insulin Resistance (2) · Menstruation Disturbances (2) · Dysmenorrhea (1) · Infertility (1) · Infertility, Female (1) · Muscle Cramp (1) · Non-alcoholic Fatty Liver Disease (1) · Oligomenorrhea (1) · Ovarian Cysts (1) · Pediatric Obesity (1) · Polycystic Ovary Syndrome (1) · Premenstrual Dysphoric Disorder (1) · Premenstrual Syndrome (1)
Genital Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Urogenital Diseases (3) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases, Female (2) · Glucose Metabolism Disorders (2) · Hyperinsulinism (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Adnexal Diseases (1) · Body Weight (1) · Cysts (1)
Metformin (2) · Bromocriptine (1) · Chorionic Gonadotropin (1) · Dexamethasone (1) · Diet, Reducing (1) · Folic Acid (1) · Inositol (1) · Ovidrel (1) · Spironolactone (1) · acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide (1) · cetrorelix (1) · semaglutide (1)
Anuja Dokras (1) · Centre for Endocrinology and Reproductive Medicine, Italy (1) · Children's Mercy Hospital Kansas City (1) · Cornell University (1) · IWK Health Centre (1) · Universitair Ziekenhuis Brussel (1) · University of California, San Diego (1) · University of Colorado, Denver (1)
United States (5) · Belgium (1) · Canada (1) · Italy (1)
Ali Imran, MD, FRCPC (1) · Anuja Dokras, MD (1) · Marco Sbracia, MD (1) · Melanie Cree-Green, MD, PhD (1) · R. Jeffery Chang, M.D. (1) · Tania Burgert, MD (1)
PMID 22197127, PMID 41359669, PMID 42014131
R01DK120612 (1), R01HD091350 (1)