15 completed, 4 unknown, 2 terminated, 1 active not recruiting. 20 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 12, Unknown 4, Terminated 2, Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Oxygen Therapy: new trials by email Literature Review of Oxygen Therapy trials Research Report on Oxygen Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The SATURİSTA Device Oxygen Therapy | Active not recruiting | Koç University | 7 | 2026-03-15 | 2026-05-08 | |
| Comparison of Physiological Effects of Two High-Flow Tracheal Oxygen Versus T-Piece During Spontaneous Breathing Trials Modified high flow tracheal oxygen-40L/min, Standard high flow tracheal oxygen-40L/min, T-piece - Critical Care, Oxygen Therapy | Not applicable | Recruiting | Jian-Xin Zhou | 20 | 2025-03-01 | 2025-03-21 |
| Comparison of Physiological Effects of Two Types of High-Flow Oxygen Therapy in Tracheostomized Patients Modified high flow tracheal oxygen, Standard high flow tracheal oxygen - Critical Care, Oxygen Therapy | Not applicable | Not yet recruiting | Jian-Xin Zhou | 20 | 2025-02-20 | 2025-02-10 |
| Airway Interventions During Intravenous Anesthesia in Children Undergoing Direct Laryngoscopy for Surgical Procedures Using High Flow Nasal Versus Low Flow Oxygen. A Pilot Study.(Flowkid) low flow oxygen with nasopharyngeal tube, high flow oxygen with OptiflowTM Nasal High Flow - Laryngoscopy, Child | Phase 4 | Completed | University Hospital, Antwerp | 20 | 2023-11-28 | 2025-07-09 |
| Initial Temperature of High Flow Nasal Cannula different starting temperature setting of HFNC - Oxygen Therapy | Not applicable | Completed | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 21 | 2023-01-18 | 2023-02-17 |
| Sustainable Preservation of Essential Oxygen Resources: A Phase 4 Crossover Study of the BUFEO System: SAVE O2 BUFEO system, Standard of Care - Oxygen Deficiency, Oxygen Therapy | Not applicable | Completed | Oxfo Corporation | 20 | 2022-11-04 | 2023-01-10 |
| Individualization Flow in Patients Treated With High Flow Nasal Therapy (iFLOW) High Flow Nasal Cannula at 30L/min, High Flow Nasal Cannula at 45L/min, High Flow Nasal Cannula at 60L/min - High-Flow Nasal Cannula, Oxygen Therapy | Not applicable | Unknown | Hospital Universitari Vall d'Hebron Research Institute | 26 | 2022-03-18 | 2022-06-02 |
| HFNC Vs LFNC in Patients with AF Undergoing RFCA Under Deep Sedation. High flow nasal cannula - Deep Sedation, Oxygen Therapy | Not applicable | Terminated | Maastricht University Medical Center | 141 | 2022-01-04 | 2025-02-20 |
| Effect of Oxygen Therapy for Patients With Precapillary Pulmonary Hypertension Who Experience an Altitude Related Adverse Health Effect (ARAHE) During 30h Exposure to 2500m Oxygen Therapy - High Altitude Pulmonary Hypertension, Oxygen Therapy | Not applicable | Completed | University of Zurich | 9 | 2021-10-18 | 2022-05-11 |
| Effects of High-Flow Nasal Cannula on Exercise Outcomes in Lung Transplant Candidates: A Pilot Study Performance Tests, Functional Tests - Pulmonary Diseases, Oxygen Therapy | Not applicable | Completed | Hospital Israelita Albert Einstein | 10 | 2021-06-02 | 2024-10-01 |
| Closed-loop Oxygen Control for High Flow Nasal Therapy Oxygen close-loop, No intervention - High Flow Nasal Cannula, Oxygen Therapy | Not applicable | Completed | Hospital Universitari Vall d'Hebron Research Institute | 53 | 2021-04-27 | 2021-12-09 |
| Comparative Study Between Liberal and Conservative Oxygen Therapy in Mechanically Ventilated Intensive Care Patients Oxygen - Oxygen Therapy | Not applicable | Completed | Aswan University Hospital | 106 | 2021-04-05 | 2024-04-30 |
| Servo Controlled Oxygen Targeting (SCO2T) Study: Masimo vs. Nellcor Servo control (closed-loop automatic control of the inspiratory fraction of oxygen (FiO2)) - IntellO2 OAM - Premature, Premature Infant | Not applicable | Completed | University of Edinburgh | 25 | 2020-11-27 | 2024-09-25 |
| High-flow Nasal Oxygen Therapy to Prevent Extubation Failure in Adult Trauma Intensive Care Patients High flow nasal oxygen - Intensive Care, Airway Extubation | Not applicable | Unknown | Hamad Medical Corporation | 450 | 2020-10-17 | 2023-10-31 |
| Impact of Prone Position in Patients Under Spontaneous Breathing on Intubation or Non-invasive Ventilation or Death Incidence During COVID-19 Acute Respiratory Distress prone position - COVID19, Oxygen Therapy | Not applicable | Completed | Centre Hospitalier Régional d'Orléans | 268 | 2020-08-28 | 2022-12-28 |
| SCO2T (Servo vs. Servo) Servo control (closed-loop automatic control of the inspiratory fraction of oxygen (FiO2)) - Leoni plus CLAC, Servo control (closed-loop automatic control of the inspiratory fraction of oxygen (FiO2)) - IntellO2 OAM - Premature Infant, Oxygen Therapy | Not applicable | Terminated | University of Edinburgh | 11 | 2020-08-10 | 2023-06-02 |
| Servo Controlled Oxygen Targeting Study Servo control - Premature Infant, Oxygen Therapy | Not applicable | Completed | University of Edinburgh | 22 | 2020-01-16 | 2022-03-14 |
| Comparing The Outcome Of High Flow Oxygen Versus Conventional Oxygen In Extubated Patients After Lung Resection. Oxygen therapy - Pulmonary Resection, Oxygen Therapy | Not applicable | Unknown | Ain Shams University | 180 | 2019-01-01 | 2022-08-23 |
| High Flow Nasal Oxygen and Acute Left Heart Failure High Flow Nasal Oxygen, Non-invasive Ventilation - Heart Failure, Noninvasive Ventilation | Not applicable | Completed | Nanjing Jiangbei People's Hospital | 123 | 2018-05-10 | 2022-04-14 |
| Effective Fraction of Inspired Oxygen With Nasal Cannula in Premature Infants Nasal cannula flow rate - Oxygen Therapy | Completed | University of Miami | 35 | 2018-04-04 | 2025-03-20 |
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Hypoxia (6) · Hyperoxia (3) · Obstetric Labor, Premature (3) · Premature Birth (3) · Pulmonary Disease, Chronic Obstructive (2) · Respiratory Insufficiency (2) · COVID-19 (1) · Heart Failure (1) · Hypercapnia (1) · Hypertension, Pulmonary (1) · Lung Diseases (1) · Lung Injury (1) · Out-of-Hospital Cardiac Arrest (1) · Pulmonary Arterial Hypertension (1) · Pulmonary edema of mountaineers (1)
Pathological Conditions, Signs and Symptoms (8) · Respiratory Tract Diseases (8) · Signs and Symptoms (7) · Signs and Symptoms, Respiratory (7) · Lung Diseases (5) · Respiration Disorders (4) · Female Urogenital Diseases and Pregnancy Complications (3) · Obstetric Labor Complications (3) · Pathologic Processes (3) · Pregnancy Complications (3) · Urogenital Diseases (3) · Cardiovascular Diseases (2) · Chronic Disease (2) · Disease Attributes (2) · Heart Diseases (2)
Oxygen (3) · Noninvasive Ventilation (1) · Prone Position (1) · Standard of Care (1)
University of Edinburgh (3) · Hospital Universitari Vall d'Hebron Research Institute (2) · Jian-Xin Zhou (2) · AGIR à Dom (1) · Ain Shams University (1) · Asan Medical Center (1) · Aswan University Hospital (1) · Breas Medical S.A.R.L. (1) · Centre Hospitalier Régional d'Orléans (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Hamad Medical Corporation (1) · Hospital Israelita Albert Einstein (1) · Koç University (1) · Maastricht University Medical Center (1) · Nanjing Jiangbei People's Hospital (1)
China (3) · France (3) · United Kingdom (3) · Egypt (2) · Spain (2) · Belgium (1) · Brazil (1) · Colombia (1) · Denmark (1) · Italy (1) · Monaco (1) · Netherlands (1) · Qatar (1) · Switzerland (1) · Turkey (Türkiye) (1)
Jian-Xin Zhou, MD, PhD (2) · Alessandro Galazzi, PhD (1) · Carlos Bazoberry, MD (1) · Chae-Man Lim, MD (1) · Deepak Jain (1) · Eduardo Bancalari (1) · Elaine Cristina Pereira (1) · Esther AC Bouman, Doctor (1) · Jean-Louis Pepin, MD, PhD (1) · Nelson Claure (1)
PMID 30166425, PMID 31723854, PMID 32694183, PMID 35422002, PMID 35534903, PMID 35803621, PMID 37330512, PMID 38079468, PMID 39293494, PMID 39707209, PMID 40962338, PMID 42618951