5 completed, 5 recruiting, 2 active not recruiting, 2 not yet recruiting. 6 Not applicable, 3 Phase 2, 2 Phase 1, 2 Phase 3.
Follow Organ Preservation: new trials by email Literature Review of Organ Preservation trials Research Report on Organ Preservation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Total Neoadjuvant Therapy With Additional Consolidation Chemotherapy Followed by Local Excision Versus Total Neoadjuvant Therapy Followed by Local Excision at Stage I Rectal Cancer TNT with additional consolidation chemotherapy followed by local excision, TNT followed by local excision - Organ Preservation, Rectal Cancer Stage I | Not applicable | Not yet recruiting | Seoul National University Hospital | 292 | 2026-06-01 | 2026-05-04 |
| Predictive Accuracy of Machine Perfusion for Kidney Transplant Outcomes in Germany Kidney Transplant, Renal Transplant | Not yet recruiting | University Hospital Heidelberg | 300 | 2026-01-19 | 2026-01-16 | |
| ZeroHeart Biopsy - Prediction of Deceased Donor Heart Transplant Performance From Organ Donors Using Pre-Transplant Biopsies - A Pilot Study Time Zero Donor Heart Biopsy for Molecular Analysis - Heart Transplantation, Graft Rejection | Recruiting | Medical University of Vienna | 50 | 2025-05-12 | 2025-05-21 | |
| Multimodal Neuromonitoring During Normothermic Regional Perfusion for Organ Donors Determined Dead by circuLatory Criteria Following Withdrawal of Life Sustaining Measures Neuromonitoring - Organ Preservation, Brain Reperfusion or Regain of Brain Function During Normothermic Regional Perfusion | Recruiting | University of British Columbia | 30 | 2025-02-24 | 2026-02-20 | |
| Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. Radiation Therapy, Chemoradiotherapy, Consolidation Chemotherapy - Rectal Cancer, Total Neoadjuvant Treatment | Phase 2 / Phase 3 | Recruiting | National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos | 400 | 2025-01-06 | 2026-05-11 |
| A Central Preservation and Assessment Service to Optimize Donor Kidney Allocation Sub-Normothermic Machine Preservation and Assessment - Organ Preservation | Active not recruiting | 34 Lives, PBC | 80 | 2024-04-19 | 2025-04-02 | |
| 10°C vs 4°C Lung Preservation RCT Lung transplantation after 10°C donor lung preservation, Lung transplantation after standard ice cooler donor lung preservation - Lung Transplant, Organ Preservation | Not applicable | Active not recruiting | University Health Network, Toronto | 317 | 2023-06-09 | 2026-03-19 |
| Long-term Outcomes After Hypothermic Oxygenated Machine Perfusion of Donor Livers Using Real-world Data Hypothermic oxygenated machine perfusion (any device) - Organ Preservation, Liver Transplantation | Completed | University Medical Center Groningen | 1202 | 2022-08-24 | 2024-04-22 | |
| Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision Contact x-ray brachytherapy, Local excision - Organ Preservation, Rectal Cancer | Not applicable | Recruiting | The Netherlands Cancer Institute | 168 | 2021-04-16 | 2023-03-17 |
| Outcomes of Transrenal Artery Perfusion Versus Transrenal Vein Perfusion Using LifePort for Deceased Donor Kidney Transplantation LifePort transrenal artery perfusion, LifePort transrenal vein perfusion - Kidney Transplantation, Organ Preservation | Not applicable | Completed | West China Hospital | 108 | 2020-01-01 | 2023-05-22 |
| Radiotherapy With Neoadjuvant Chemotherapy and Immunotherapy in Rectal Cancer Chemotherapy, Immunotherapy, IMRT - Rectal Cancer, Radiotherapy | Phase 1 / Phase 2 | Suspended | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 30 | 2019-11-01 | 2024-01-03 |
| Treatment Strategy for Rectal Cancer Patients With Complete Clinical Response standard TME surgery - Rectal Cancer, Organ Preservation | Completed | Yuan-hong Gao | 513 | 2018-01-01 | 2023-04-14 | |
| Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery Complete responders and Non-complete responders, Chemoradiation + EBRT Boost, Chemoradiation + HDRBT Boost - Stage II Rectal Cancer, Organ Preservation | Phase 2 / Phase 3 | Recruiting | Sir Mortimer B. Davis - Jewish General Hospital | 131 | 2017-04-25 | 2026-06-30 |
| Ex Vivo Lung Perfusion : Effect of Cellular Perfusate on Mechanical Properties and Gas Exchange Function of Donor Lungs Red blood cells - Organ Preservation | Not applicable | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 6 | 2016-10-01 | 2016-11-02 |
| Functional Organ Preservation Surgery FOPS, CRT - Organ Preservation | Not applicable | Completed | Asan Medical Center | 264 | 2010-09-01 | 2019-07-09 |
| Vasosol Organ Perfusion Solution and Medtronic Portable Bypass System Vasosol Organ Perfusion Solution and Medtronic Portable Bypass System - Liver Transplantation, Organ Preservation | Phase 1 | Completed | Polyak, Maximilian | 20 | 2004-07-01 | 2009-04-09 |
Rectal Neoplasms (6) · Fatigue (1) · Laryngeal Diseases (1) · Low Anterior Resection Syndrome (1) · Postoperative Complications (1) · Radiation Injuries (1)
Colorectal Neoplasms (6) · Digestive System Diseases (6) · Digestive System Neoplasms (6) · Gastrointestinal Diseases (6) · Gastrointestinal Neoplasms (6) · Intestinal Diseases (6) · Intestinal Neoplasms (6) · Neoplasms (6) · Neoplasms by Site (6) · Rectal Diseases (6) · Colonic Diseases (1) · Otorhinolaryngologic Diseases (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Respiratory Tract Diseases (1)
Chemoradiotherapy (2) · Consolidation Chemotherapy (1) · Drug Therapy (1) · Erythrocyte Count (1) · Immunotherapy (1) · Mastectomy, Segmental (1) · Radiotherapy (1) · Restraint, Physical (1) · Surgical Procedures, Operative (1) · Trinitrotoluene (1)
34 Lives, PBC (1) · Asan Medical Center (1) · Medical University of Vienna (1) · National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos (1) · Polyak, Maximilian (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Seoul National University Hospital (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · The Netherlands Cancer Institute (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University Health Network, Toronto (1) · University Hospital Heidelberg (1) · University Medical Center Groningen (1) · University of British Columbia (1) · West China Hospital (1)
Canada (3) · China (3) · United States (3) · Austria (2) · Netherlands (2) · South Korea (2) · Switzerland (2) · Australia (1) · Belgium (1) · France (1) · India (1) · Lithuania (1) · Spain (1)
Audrius Dulskas, PhD (1) · Brechtje A Grotenhuis, MD, PhD (1) · Chris Jaynes (1) · Elliot Wakeam, MD MPH (1) · Goverdhan D Puri, MD, PhD (1) · James V. Guarrera, M.D. (1) · Jong-Lyel Roh, MD (1) · Pim Burger, MD, PhD (1) · Te Vuong, MD (1) · Vincent E de Meijer, MD, PhD (1) · Yuan-hong Gao, MD (1)
PMID 38159950, PMID 38742842, PMID 38969242, PMID 38979743, PMID 40772946, PMID 41737541