35 completed, 25 recruiting, 21 unknown, 15 active not recruiting. 40 Not applicable, 30 Phase 2, 15 Phase 3, 5 Phase 1, 1 Early Phase 1.
Follow Mastectomy, Segmental: new trials by email Literature Review of Mastectomy, Segmental trials Research Report on Mastectomy, Segmental
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis Biopsy Procedure, Biospecimen Collection, Breast Conservation Treatment - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Positive Breast Carcinoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 562 | 2027-03-09 | 2026-10-13 |
| BIOmarker Based Diagnostic TOOLkit to Personalise Pharmacological Approaches in Congestive Heart Failure: the BIOTOOL-CHF Validation Trial Intervention: diuretic therapy guided by the Biological Congestion Score (BCS) using a predefined treatment nomogram - Congestive Heart Failure(CHF) | Not applicable | Not yet recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 600 | 2026-12-15 | 2026-08-31 |
| Postoperative Pulmonary Function Assessment Based on Deep Learning Study Segmentectomy, Lobectomy, Bronchoscopic Ablation - Lung Cancer (NSCLC) | Not applicable | Not yet recruiting | Chinese University of Hong Kong | 192 | 2026-11-01 | 2026-10-21 |
| Phase 3 Trial of SRG-514 Administered Intraoperatively to Patients Undergoing Breast-Conserving Surgery BCS + SRG-514, BCS - TNBC - Triple-Negative Breast Cancer | Phase 3 | Not yet recruiting | SURGE Therapeutics | 400 | 2026-10-01 | 2026-07-23 |
| Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer Neoadjuvant Chemotherapy, Radiation Therapy, MRI - Breast Cancer, HER2-positive Breast Cancer | Phase 1 / Phase 2 | Not yet recruiting | Ohio State University Comprehensive Cancer Center | 84 | 2026-09-15 | 2026-06-24 |
| Dynamic Prediction of Sleep Protection Demand on the First Postoperative Night and Its Influence on Ward Process After Thoracoscopic Lobectomy or Segmentectomy Video-assisted thoracoscopic (VATS) lobectomy or segmentectomy - Postoperative Sleep Disturbance | Not yet recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 400 | 2026-07-23 | 2026-07-21 | |
| Safety of Breast-Conserving Surgery for Multifocal or Multicentric Breast Cancer Breast-conserving surgery, postoperative radiotherapy and individualized adjuvant systemic therapy - Breast Cancer | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 100 | 2026-07-15 | 2026-07-01 | |
| Cryoablation Versus Lumpectomy in Early-Stage Breast Cancer Percutaneous cryoablation, Breast-conserving surgery - Early-Stage Breast Cancer | Phase 3 | Not yet recruiting | Franciscus Gasthuis & Vlietland (Hospital) | 938 | 2026-04-01 | 2026-03-19 |
| Acellular Dermal Matrix(SureDerm BCS) in Breast-Conserving Surgery for Breast Cancer Patients Acellular Dermal Matrix (SureDerm BCS), Standard Breast-Conserving Surgery - Breast Neoplasms, Mastectomy, Segmental | Not applicable | Not yet recruiting | Seoul St. Mary's Hospital | 116 | 2026-01-08 | 2026-01-15 |
| Ablation Compare With Surgery for Early Breast Cancer breast conserving surgery, cryo-thermal ablation - Breast Cancer, Early Stage | Not applicable | Recruiting | Peking University People's Hospital | 264 | 2026-01-01 | 2026-03-19 |
| The Impact of Surgeon-Interpreted Intraoperative Margin Assessment During Breast Conserving Surgery on Postoperative Treatment Pegulicianine Fluorescence-Guided Surgery, Digital Breast Tomosynthesis, Breast Conserving Therapy - Breast Cancer | Suspended | M.D. Anderson Cancer Center | 175 | 2025-10-09 | 2026-10-07 | |
| Segmentectomy vs Lobectomy for 2 - 3cm IASLC Grade 1-2 Lung Adenocarcinoma: A Multi-center RCT Pulmonary segmentectomy - Lung Adenocarcinoma | Phase 3 | Not yet recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 587 | 2025-10-01 | 2025-09-12 |
| A Study of Surgery and Radiotherapy in People With Breast Cancer Lumpectomy or mastectomy, Radiotherapy, Trastuzumab, Pertuzumab, Paclitaxel, or a combination of these drugs - Metastatic Breast Cancer, HER2-positive Breast Cancer | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 178 | 2025-09-17 | 2026-05-14 |
| Robotic-Assisted Total Knee Arthroplasty: Cruciate-Retaining Versus Bi-Cruciate Stabilized Robotic assisted Cruciate-Retaining (CR) TKA procedures, Robotic assisted Bi-Cruciate Stabilized (BCS) TKA procedures - Knee Osteoarthritis, Total Knee Arthroplasty | Not applicable | Not yet recruiting | Chinese University of Hong Kong | 60 | 2025-06-01 | 2025-06-24 |
| Axillary Nodal Burden in HER2+ and TNBC Breast conserving surgery with axillary surgery - Breast Cancer | Completed | Gangnam Severance Hospital | 1571 | 2025-06-01 | 2025-10-08 | |
| Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer Biopsy of Breast, Biospecimen Collection, Breast Surgery - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Recruiting | Mayo Clinic | 120 | 2025-05-14 | 2026-09-03 |
| Trial Studying Chemotherapy in Nigerian Women With Triple Negative Breast Cancer Cyclophosphamide, Epirubicin, Docetaxel - Triple Negative Breast Cancer | Phase 2 | Recruiting | University of Chicago | 85 | 2025-03-18 | 2026-02-17 |
| CRYoablation for Small Tumors As Local Treatment - SIX Trial cryoablation, Breast Surgery (Lumpectomy or Mastectomy) - Breast Cancer, Breast Neoplasm | Phase 3 | Recruiting | Hospital do Coracao | 750 | 2025-03-01 | 2025-06-26 |
| SEgmentectomy Versus Lobectomy in T1C Non-Small Cell Lung Cancer (SELTIC) Segmentectomy, Lobectomy - Non-Small Cell Lung Cancer | Not applicable | Not yet recruiting | Istanbul University - Cerrahpasa | 400 | 2025-01-02 | 2024-10-17 |
| Segmentectomy After Induction Therapy (SAINT) Segmentectomy - Segmentectomy | Not applicable | Recruiting | Northwestern University | 25 | 2024-08-02 | 2026-05-26 |
Showing 20 of 124. Sign in to see all of them.
Breast Neoplasms (71) · Rectal Neoplasms (10) · Triple Negative Breast Neoplasms (9) · Carcinoma, Non-Small-Cell Lung (8) · Adenocarcinoma of Lung (6) · Carcinoma, Intraductal, Noninfiltrating (6) · Lung Neoplasms (6) · Breast Carcinoma In Situ (4) · Pain, Postoperative (3) · Pancreatic Neoplasms (2) · Recurrence (2) · Adenocarcinoma, Bronchiolo-Alveolar (1) · Amenorrhea (1) · Anisomastia (1) · Aphasia (1)
Washington University School of Medicine (5) · Stanford University (4) · Fudan University (3) · Peking University Cancer Hospital & Institute (3) · Shanghai Pulmonary Hospital, Shanghai, China (3) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (3) · The First Affiliated Hospital with Nanjing Medical University (3) · The Netherlands Cancer Institute (3) · Vanderbilt-Ingram Cancer Center (3) · Alliance for Clinical Trials in Oncology (2) · Cedars-Sinai Medical Center (2) · Chinese University of Hong Kong (2) · H. Lee Moffitt Cancer Center and Research Institute (2) · Masonic Cancer Center, University of Minnesota (2) · Memorial Sloan Kettering Cancer Center (2)
United States (43) · China (24) · Italy (5) · South Korea (5) · Canada (4) · Netherlands (4) · Turkey (Türkiye) (4) · Germany (3) · Spain (3) · United Kingdom (3) · Austria (2) · Brazil (2) · France (2) · Hong Kong (2) · Hungary (2)
Alice Chung, MD (2) · Fengxi Su, M.D. (2) · Haiquan Chen, M.D. (2) · Todd M. Tuttle, MD (2) · A. Bapsi Chakravarthy, MD (1) · Aiping Shi, Doctor (1) · Akif Turna, MD, PhD (1) · Alexandre Biasi Cavalcante, PhD (1) · Alice Police, MD (1) · Alison Estabrook, MD (1) · Andreas Kohler, MD (1) · Anees Chagpar, MD (1) · Anita Mamtani, MD (1) · Ankit Bharat, M.D. (1)
PMID 19638905, PMID 19644246, PMID 20362507, PMID 21752720, PMID 21774104, PMID 21904959, PMID 22300861, PMID 23744869, PMID 24595800, PMID 27322859, PMID 28749045, PMID 29880292, PMID 30442588, PMID 31243811, PMID 31927716, PMID 32249491, PMID 32571746, PMID 32715776, PMID 33242536, PMID 33567141, PMID 33591469, PMID 34086171, PMID 34266694, PMID 34356979, PMID 34384695, PMID 35766394, PMID 36048535, PMID 36158516, PMID 36223740, PMID 36609389, PMID 36780674, PMID 36796498, PMID 37028614, PMID 37848916, PMID 37870228, PMID 38039432, PMID 38159950, PMID 38215351, PMID 38345718, PMID 38417440, PMID 38960464, PMID 38979716, PMID 39297720, PMID 39636623, PMID 40045324, PMID 40532782, PMID 40605595, PMID 41056841, PMID 41891787, PMID 42001600
P30CA068485 (2), P30CA060553 (1), P30CA124435 (1), R01CA273246 (1), R44CA206801 (1), U10CA037447 (1), U10CA180820 (1), U10CA180888 (1), UM1CA186689 (1), UM1CA186704 (1)