7 completed, 4 recruiting, 3 not yet recruiting, 3 unknown. 6 Not applicable, 4 Phase 2, 3 Phase 1, 1 Early Phase 1, 1 Phase 4.
Follow Optic Neuropathy: new trials by email Literature Review of Optic Neuropathy trials Research Report on Optic Neuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Teprotumumab N01 Versus Methylprednisolone After Urgent Orbital Decompression for Dysthyroid Optic Neuropathy Teprotumumab N01, Intravenous Methylprednisolone (IVMP) - Thyroid Eye Disease, TED, Graves Ophthalmopathy | Phase 2 | Not yet recruiting | Sun Yat-sen University | 60 | 2026-08-01 | 2026-05-19 |
| Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is Suspected Optic Neuritis, Optic Neuropathy | Recruiting | First Affiliated Hospital of Guangxi Medical University | 500 | 2025-01-06 | 2026-09-25 | |
| Repetitive Transorbital Alternating Current Stimulation for Optic Neuropathies SAVIR Alpha Synch mobile (SASm) - Optic Neuropathy | Not applicable | Recruiting | NYU Langone Health | 70 | 2024-11-18 | 2026-02-27 |
| Clinical Study of FB1001 in Patients FB1001 - Optic Neuropathy, NAION - Non-Arteritic Ischemic Optic Neuropathy | Phase 1 | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 59 | 2024-08-15 | 2024-07-17 |
| Building Research With Artificial Intelligence in Neuro-Ophthalmology Deep learning algorithm applied on retrospectively collected color fundus photographs - Optic Neuropathy, Optic Neuropathy, Ischemic | Completed | Fondation Ophtalmologique Adolphe de Rothschild | 693 | 2023-10-01 | 2025-09-08 | |
| STReetlab Assessment Tool of Activities Daily Living in Glaucoma Patient Pilot Phase: standardized behavioral task, Validation Phase: standardized behavioral task - Optic Neuropathy | Not applicable | Not yet recruiting | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts | 100 | 2023-03-01 | 2023-02-28 |
| Hyperbaric Oxygen Therapy for Optic Neuropathies Hyperbaric Oxygen, Sham Hyperbaric Oxygen - Optic Neuropathy, Glaucoma | Not applicable | Recruiting | Stanford University | 60 | 2022-11-01 | 2026-10-09 |
| Effect of Intraocular Tamponade on Visual Perception Electroretinogram, Vitrectomy operation - Retinal Detachment, Optic Neuropathy | Not applicable | Unknown | Benha University | 60 | 2022-09-12 | 2022-09-16 |
| Neuromuscular Ultrasonography Assessment of Optic Nerve in Systemic Lupus Eryhematosus Optic Neuropathy | Completed | Amira M elSonbaty | 140 | 2022-01-01 | 2024-07-03 | |
| Subcutaneous Injection of Erythropoietin on Visual Functions in Patients With Late Onset Optic Neuropathy erythropoietin - Optic Neuropathy | Phase 1 / Phase 2 | Completed | Alexandria University | 20 | 2019-04-01 | 2021-04-01 |
| Assessment of Visual Function With a Portable Brain-computer Interface nGoggle - Glaucoma, Age Related Macular Degeneration | Unknown | NGoggle | 200 | 2019-02-11 | 2020-02-27 | |
| Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple Sclerosis CNM-Au8, Placebo - Relapsing Remitting Multiple Sclerosis, Optic Neuropathy | Phase 2 | Terminated | Clene Nanomedicine | 73 | 2018-11-23 | 2023-04-03 |
| BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases Visual Performance tests, Brain-computer interface - Glaucoma, Macular Degeneration | Not applicable | Completed | University of Miami | 115 | 2018-10-29 | 2024-11-26 |
| BIOtinidase Test In Optic-Neuropathy Biotin Deficiency, Optic Neuropathy | Completed | Fondation Ophtalmologique Adolphe de Rothschild | 12 | 2017-07-26 | 2018-10-18 | |
| Biomechanics of Optic Neuropathy magnetic resonance image (MRI), Optical Coherence Tomography (OCT) - Optic Neuropathy | Terminated | University of Miami | 10 | 2016-09-01 | 2020-10-23 | |
| Stem Cell Ophthalmology Treatment Study II Arm 1 - Retinal Disease, Age-Related Macular Degeneration | Not applicable | Recruiting | MD Stem Cells | 500 | 2016-01-01 | 2026-06-29 |
| Comparing Rates of Glaucoma in Professional Wind Versus Non-Wind Instrument Players Glaucoma, Intraocular Pressure | Completed | Wills Eye | 51 | 2015-07-01 | 2016-11-22 | |
| Treatment of Optic Neuropathies Using Autologous Bone Marrow-Derived Stem Cells Stem Cells - Optic Neuropathy | Phase 1 / Phase 2 | Unknown | Stem Cells Arabia | 100 | 2013-04-01 | 2020-03-17 |
| Optic Neuropathy in 10 Patients With Glioblastoma Receiving Bevacizumab Bevacizumab (Avastin) - Glioblastoma, Optic Neuropathy | Early Phase 1 | Withdrawn | West Penn Allegheny Health System | 2011-03-01 | 2021-12-09 | |
| Use of Bevacizumab in Trabeculectomy Surgery Bevacizumab, Control - Glaucoma, Optic Neuropathy | Phase 4 | Completed | Sunnybrook Health Sciences Centre | 59 | 2010-06-01 | 2023-08-21 |
Optic Nerve Diseases (20) · Glaucoma (8) · Macular Degeneration (3) · Optic Neuropathy, Ischemic (3) · Ocular Hypertension (2) · Optic Atrophy (2) · Optic Atrophy, Hereditary, Leber (2) · Optic Neuritis (2) · Retinal Degeneration (2) · Vision Disorders (2) · Biotin deficiency (1) · Blindness (1) · Brain Neoplasms (1) · Cone Dystrophy (1) · Cone-Rod Dystrophies (1)
Cranial Nerve Diseases (20) · Nervous System Diseases (20) · Eye Diseases (19) · Ocular Hypertension (7) · Eye Diseases, Hereditary (5) · Autoimmune Diseases (3) · Cardiovascular Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Immune System Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Retinal Diseases (3) · Vascular Diseases (3) · Autoimmune Diseases of the Nervous System (2) · Demyelinating Autoimmune Diseases, CNS (2)
Bevacizumab (2) · Brain-Computer Interfaces (1) · Electroretinography (1) · Erythropoietin (1) · Hyperbaric Oxygenation (1) · Magnetic Resonance Imaging (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Sodium Chloride (1) · Tomography, Optical Coherence (1) · teprotumumab (1)
Fondation Ophtalmologique Adolphe de Rothschild (2) · University of Miami (2) · Alexandria University (1) · Amira M elSonbaty (1) · Benha University (1) · Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (1) · Clene Nanomedicine (1) · First Affiliated Hospital of Guangxi Medical University (1) · MD Stem Cells (1) · NGoggle (1) · NYU Langone Health (1) · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (1) · Stanford University (1) · Stem Cells Arabia (1) · Sun Yat-sen University (1)
United States (8) · China (3) · Egypt (3) · Canada (2) · France (2) · Australia (1) · Austria (1) · Jordan (1) · United Arab Emirates (1)
Adeeb AlZoubi, PhD (1) · Ahmed A Tabl, MD (1) · Byron R Lam, MD (1) · Catherine Birt, MD, FRCSC (1) · Felipe A Medeiros, MD, PhD (1) · Heidi Beadnall, MD (1) · Henry Tseng, MD, PhD (1) · Henry Tseng, PhD (1) · Jeffrey L Goldberg, MD PhD (1) · Jeffrey Weiss, MD (1) · Jonathan Williams, MD (1) · L J Katz, MD (1) · Mai ElBahwash, PhD (1)
PMID 26199618, PMID 26604914, PMID 27857759, PMID 27904503, PMID 29270420, PMID 30050918, PMID 31119146, PMID 31620478, PMID 32039263, PMID 32231088, PMID 33546345, PMID 40576025
R01EY029885 (1), R42EY027651 (1)