134 completed, 13 terminated, 8 unknown, 5 recruiting. 54 Phase 3, 43 Phase 4, 39 Phase 2, 17 Not applicable, 11 Phase 1.
Follow Open-Angle Glaucoma: new trials by email Literature Review of Open-Angle Glaucoma trials Research Report on Open-Angle Glaucoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Outcomes Following Bio-Reinforced Canaloplasty in Eyes With Open-Angle Glaucoma AlloSpan Canal Platform Bio-Reinforced Canaloplasty - Open-Angle Glaucoma | Enrolling by invitation | Iantrek, Inc. | 300 | 2026-04-01 | 2026-10-13 | |
| Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options NEI-VFQ-25 (National Eye Institute Visual Function Questionnaire-25). - Glaucoma Eye, Open-angle Glaucoma | Recruiting | Hospices Civils de Lyon | 132 | 2026-02-23 | 2026-03-16 | |
| Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use Durysta, Bimatoprost Intracameral Implant 10 µg - Glaucoma, Open-Angle Glaucoma | Phase 4 | Recruiting | University of Miami | 20 | 2026-02-09 | 2026-03-05 |
| This Follow-up Extension Study is Aimed to Monitor the Long-term IOP-lowering Performance/Efficacy and Safety of the MINT® Procedure in Open Angle Glaucoma Eyes. MINT Minimally Invasive Nasal Trabeculostomy - Glaucoma, Ocular Hypertension | Not applicable | Completed | Sanoculis Ltd | 47 | 2025-06-16 | 2026-10-15 |
| Efficacy of Surgical Systems in Combination With Phacoemulsification: a Retrospective Analysis Real-World efficacy of Hydrus Microstent with OMNI Surgical System in combination with Phacoemulsification: a retrospective analysis - Open-Angle Glaucoma | Recruiting | Barnet Dulaney Perkins Eye Centers | 300 | 2025-03-31 | 2025-05-01 | |
| Vitamin Mix (B6, B9, B12, And Choline) For Glaucoma Patients Vitamin B-mix, Standard Care - Open-angle Glaucoma, Pseudoexfoliation Glaucoma | Not applicable | Recruiting | Karolinska Institutet | 80 | 2025-03-31 | 2025-04-29 |
| Selective, Micropulse and Pattern Laser Trabeculoplasty in Medically Treated Open-angle Glaucoma. Selective laser trabeculoplasty, Micropulse laser trabeculoplasty, Pattern laser trabeculoplasty - Open-Angle Glaucoma, Ocular Hypertension | Not applicable | Completed | University of Udine | 90 | 2025-02-01 | 2026-08-10 |
| A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma Oral semaglutide, Placebo - Primary Open Angle Glaucoma (POAG), Open-Angle Glaucoma | Phase 4 | Recruiting | Glostrup University Hospital, Copenhagen | 126 | 2025-01-01 | 2025-01-24 |
| A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes Bimatoprost Ophthalmic Solution, 0.01%, LUMIGAN® (bimatoprost ophthalmic solution) 0.01% - Open-angle Glaucoma, Ocular Hypertension | Phase 1 | Unknown | Amneal Pharmaceuticals, LLC | 240 | 2024-04-01 | 2024-08-06 |
| A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation In Adult Participants With Open-Angle Glaucoma in China XEN45 Glaucoma Treatment System, Trabeculectomy - Open-angle Glaucoma, OAG | Phase 4 | Active not recruiting | AbbVie | 120 | 2024-01-09 | 2026-04-28 |
| A Study of PER-001 in Participants With Open-Angle Glaucoma PER-001 Intravitreal Implant - Low Dose, PER-001 Intravitreal Implant - High Dose, PER-001 Intravitreal Implant - Sham - Open-angle Glaucoma | Phase 1 / Phase 2 | Completed | Perfuse Therapeutics, Inc. | 33 | 2023-05-25 | 2026-06-05 |
| Efficacy and Safety of Trabecular Meshwork Microstent Drainage System ( MicroCOGO ) Trabecular Meshwork Microstent Drainage System, phacoemulsification - Open-angle Glaucoma, Cataract | Not applicable | Active not recruiting | Healthguard Biomed | 207 | 2022-10-19 | 2024-12-19 |
| Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle Glaucoma XEN45 (Glaucoma Gel Stent) - Open-Angle Glaucoma | Phase 3 | Completed | AbbVie | 74 | 2022-07-22 | 2026-02-27 |
| Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension Nebivolol Ophthalmic Suspension 1 Percent, Nebivolol Ophthalmic Suspension 0.5 Percent, Timolol Ophthalmic Suspension 0.5 Percent - Open-Angle Glaucoma, Ocular Hypertension | Phase 2 | Completed | Betaliq, Inc. | 226 | 2021-04-15 | 2024-04-17 |
| 18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA) Open-angle Glaucoma, Ocular Hypertension | Completed | Allergan | 220 | 2021-03-03 | 2025-08-03 | |
| AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension AGN-193408 SR, Lumigan, Sham Administration - Open-angle Glaucoma, Ocular Hypertension | Phase 1 / Phase 2 | Active not recruiting | AbbVie | 100 | 2020-11-16 | 2026-05-22 |
| Effect of MEMOPTIC on Visual Field of Patients Followed for a Chronic Open-angle Glaucoma MEMOPTIC, usual treatment of glaucoma - Open-angle Glaucoma, Visual Field | Not applicable | Terminated | Centre Hospitalier Universitaire, Amiens | 15 | 2020-09-21 | 2026-06-12 |
| A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension Bimatoprost SR, LUMIGAN - Open-Angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | AbbVie | 37 | 2020-06-11 | 2023-06-08 |
| African Glaucoma Laser Trial Selective laser trabeculoplasty (SLT), Latanoprost ophthalmic solution, Timolol ophthalmic solution - Open-angle Glaucoma | Phase 4 | Withdrawn | West Virginia University | 2019-09-01 | 2021-06-21 | |
| Long-term Safety and Efficacy Extension Trial of Bimatoprost SR Bimatoprost SR, Standard of Care - Open-Angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | AbbVie | 455 | 2019-03-27 | 2026-07-15 |
Showing 20 of 170. Sign in to see all of them.
Glaucoma, Open-Angle (170) · Ocular Hypertension (119) · Glaucoma (50) · Hypertension (16) · Cataract (5) · Exfoliation Syndrome (2) · Cardiovascular Diseases (1) · Diabetic Retinopathy (1) · Eye Diseases (1) · Glaucoma, Angle-Closure (1) · Low Tension Glaucoma (1) · Papilledema (1) · Patient Compliance (1) · Vascular Diseases (1)
Eye Diseases (169) · Glaucoma (120) · Ocular Hypertension (51) · Cardiovascular Diseases (16) · Vascular Diseases (16) · Lens Diseases (5) · Iris Diseases (2) · Optic Nerve Diseases (2) · Uveal Diseases (2) · Behavior (1) · Cranial Nerve Diseases (1) · Diabetes Complications (1) · Diabetes Mellitus (1) · Diabetic Angiopathies (1) · Endocrine System Diseases (1)
Travoprost (34) · Timolol (31) · Latanoprost (23) · Ophthalmic Solutions (22) · brinzolamide (18) · Brimonidine Tartrate (14) · Bimatoprost (10) · Duotrav (10) · dorzolamide (10) · dorzolamide-timolol combination (8) · anecortave acetate (5) · netarsudil (5) · tafluprost (5) · Phacoemulsification (4) · Solutions (4)
Alcon Research (68) · Glaukos Corporation (12) · Allergan (11) · AbbVie (7) · Aerie Pharmaceuticals (6) · Pharmaceutical Research Network (5) · Santen Oy (5) · Santen Inc. (4) · Mati Therapeutics Inc. (3) · National Eye Institute (NEI) (3) · Bausch & Lomb Incorporated (2) · Bp Consulting, Inc (2) · Santen Pharmaceutical Co., Ltd. (2) · Vistakon Pharmaceuticals (2) · Aeon Astron Europe B.V. (1)
United States (65) · Germany (10) · Spain (8) · Armenia (7) · China (7) · Canada (6) · Japan (5) · Australia (4) · Belgium (4) · Finland (4) · Italy (4) · Poland (4) · United Kingdom (4) · Brazil (3) · Denmark (3)
William C. Stewart, MD (6) · Lilit A Voskanyan, MD, PhD (5) · Theresa Landry (5) · Theresa Landry, PhD (4) · James Teague, BS, Sr. Clinical Manager (3) · Severine Durier, Pharm.D (3) · Theresa Heah, MD (3) · Auli Ropo, M.D. (2) · Elizabeth D. Sharpe, MD (2) · Jason Vittitow (2) · Oscar Cuzanni, MD, MSc (2) · Pamela Smith, B.S. (2)
PMID 35943114, PMID 19476406, PMID 29194198, PMID 32166538, PMID 11589866, PMID 14736774, PMID 14996520, PMID 17415690, PMID 18414108, PMID 18538406, PMID 18826749, PMID 19049301, PMID 19152871, PMID 19365194, PMID 20207977, PMID 20828829, PMID 21843876, PMID 22310086, PMID 22814041, PMID 23579344, PMID 24727262, PMID 24906863, PMID 25430900, PMID 25432143, PMID 25447269, PMID 26563363, PMID 26875002, PMID 27210275, PMID 28408039, PMID 29476443, PMID 29802818, PMID 31981106, PMID 33250082, PMID 35643967, PMID 36912740, PMID 37343625, PMID 39946034, PMID 39985740, PMID 41084053, PMID 9098273
2018 (2), 2023 (2), 2015 (1), 2016 (1)