11 completed, 1 recruiting, 1 unknown. 5 Phase 3, 3 Phase 1, 2 Phase 4, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 5 |
| Phase 1 | 3 | Completed 3 |
| Phase 4 | 2 | Completed 2 |
| Not applicable | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Pattern of Dry Eye Disease After Cataract Surgery Artificial tears (sodium hyaluronate 0.2%) - Dry Eye Disease, Cataract | Recruiting | Lithuanian University of Health Sciences | 100 | 2024-03-01 | 2024-03-07 | |
| Prevalence of Glaucoma in Belgium: a Multicenter National Trial AI algorithm for the detection of glaucoma - Glaucoma | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 1418 | 2023-03-08 | 2023-05-31 |
| Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery Diquafosol - Dry Eye | Unknown | Mun Wai Lee | 50 | 2021-01-01 | 2021-07-07 | |
| Efficacy and Safety of Ikervis Under Controlled Environmental Conditions Environment IKERVIS®1mg/mL - Dry Eye, Dry Eye Syndromes | Phase 4 | Completed | Instituto Universitario de OftalmobiologĂa Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 25 | 2020-02-04 | 2021-04-21 |
| Preservative-free Tafluprost/Timolol Fixed Combination: Morning vs Evening Dosing Tafluprost/timolol fixed combination - Glaucoma, Open-Angle | Phase 4 | Completed | Aristotle University Of Thessaloniki | 42 | 2017-01-01 | 2020-12-17 |
| A Study to Evaluate Pharmacokinetics of Tafluprost Ophthalmic Solution (0.0015%) in Pediatric Patients With Glaucoma or Ocular Hypertension Preservative free tafluprost opthalmic solution - Glaucoma, Ocular Hypertension | Phase 1 | Completed | Santen Oy | 17 | 2014-06-01 | 2017-10-10 |
| Pharmacokinetics, Safety and Tolerability of the Preservative-free Fixed Dose Combination of Tafluprost 0.0015% and Timolol 0.5% Eye Drops Preservative free tafluprost 0.0015% eye drops, Preservative free timolol 0.5% eye drops, Preservative free FDC of tafluprost 0.0015% and timolol 0.5% eye drops - Healthy Volunteers | Phase 1 | Completed | Santen Oy | 15 | 2011-09-01 | 2012-06-08 |
| Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrations Timolol and Tafluprost, Fixed Dose Combination of tafluprost and timolol - Ocular Hypertension, Open-angle Glaucoma | Phase 3 | Completed | Santen Oy | 401 | 2011-03-01 | 2012-06-08 |
| Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies Timolol/ FDC/ Placebo/ Tafluprost - Ocular Hypertension, Open-angle Glaucoma | Phase 3 | Completed | Santen Oy | 600 | 2011-02-01 | 2013-03-13 |
| Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Drops tafluprost - Ocular Hypertension, Open-Angle Glaucoma | Phase 3 | Completed | Santen Oy | 185 | 2010-04-01 | 2013-05-31 |
| Interaction Study of Timolol Eye Drops and Paroxetine Capsules Paroxetine, Placebo, timolol maleate - Healthy | Phase 1 | Completed | Santen Oy | 12 | 2009-04-01 | 2010-01-28 |
| Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops tafluprost - Ocular Hypertension, Open-Angle Glaucoma | Phase 3 | Completed | Santen Oy | 150 | 2008-01-01 | 2009-01-12 |
| Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulation Tafluprost 0.0015% - Open-Angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | Santen Oy | 43 | 2005-09-01 | 2010-12-28 |
Glaucoma, Open-Angle (6) · Ocular Hypertension (6) · Dry Eye Syndromes (3) · Glaucoma (2) · Cataract (1) · Keratitis (1)
tafluprost (5) · Timolol (4) · Ophthalmic Solutions (1) · Paroxetine (1) · diquafosol (1)
Finland (5) · Belgium (1) · Germany (1) · Greece (1) · Hungary (1) · Lithuania (1) · Malaysia (1) · Spain (1) · United Kingdom (1) · United States (1)
Auli Ropo, M.D. (2) · Auli Ropo (1) · Clemens Vass, M.D. (1) · Eva Ruzickova, M.D. (1) · Evgeniy Egorov, Professor (1) · Guna Laganovska, M.D. (1) · Hannu Uusitalo, M.D., Prof. (1) · Hannu Uusitalo, Professor (1) · Ingeborg Stalmans, MD, PhD (1) · Janne Backman, MD, PhD (1) · Juhani Airaksinen, Prof. (1) · Maria L. Ribeiro, M.D. (1) · Marieta Kostianeva, M.D. (1)