16 completed, 8 terminated, 2 withdrawn, 1 no longer available. 15 Phase 2, 10 Phase 3, 3 Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 10, Terminated 3, Withdrawn 2 |
| Phase 3 | 10 | Completed 5, Terminated 4, Withdrawn 1 |
| Phase 1 | 3 | Completed 3 |
| Not applicable | 1 | Terminated 1 |
Follow anecortave acetate: new trials by email Literature Review of anecortave acetate trials Research Report on anecortave acetate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anecortave Acetate Injection to Treat Steroid-responsive Intraocular Pressure Increase in Cornea Transplant Patients anecortave acetate, 30 mg anecortave acetate - Transplant, Intraocular Pressure | Not applicable | Terminated | Cornea Research Foundation of America | 7 | 2009-05-01 | 2018-08-14 |
| A Dose-Volume Study of a Treatment for Elevated IOP Due to Open-Angle Glaucoma or Ocular Hypertension Anecortave Acetate Sterile Suspension, 6 mg/mL, Anecortave Acetate Sterile Suspension, 3.75 mg/mL, Anecortave Acetate Sterile Suspension, 96 mg/mL - Open-Angle Glaucoma, Ocular Hypertension | Phase 2 | Terminated | Alcon Research | 197 | 2008-12-01 | 2012-11-30 |
| Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension Anecortave Acetate Sterile Suspension, 30 mg/mL, Anecortave Acetate Sterile Suspension, 60 mg/mL, Anecortave Acetate Sterile Suspension, 75 mg/mL - Open-angle Glaucoma, Oular Hypertension | Phase 2 / Phase 3 | Completed | Alcon Research | 201 | 2008-06-01 | 2012-11-28 |
| A Multi-Dose Study With a Treatment for Open-Angle Glaucoma Anecortave Acetate, Placebo - Open-Angle Glaucoma | Phase 2 / Phase 3 | Withdrawn | Alcon Research | 2008-05-01 | 2012-05-30 | |
| Treatment of Chronic Central Serous Chorioretinopathy With Open-Label Anecortave Acetate Anecortave Acetate Sterile suspension 15 mg, Anecortave Acetate - Chronic Central Serous Chorioretinopathy | Phase 1 / Phase 2 | Completed | Manhattan Eye, Ear & Throat Hospital | 5 | 2007-05-01 | 2012-10-25 |
| Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma Anecortave Acetate Sterile Suspension, 30 mg/mL, Anecortave Acetate Vehicle - Open-angle Glaucoma | Phase 2 | Completed | Alcon Research | 89 | 2007-03-01 | 2012-11-28 |
| Anecortave Acetate in Subfoveal Choroidal Neovascularization (CNV) Due to Wet Age-Related Macular Degeneration (AMD) Anecortave Acetate 15 mg sterile suspension, Anecortave Acetate Vehicle - Macular Degeneration, Maculopathy, Age-Related | Phase 3 | Completed | Alcon Research | 291 | 2007-01-01 | 2012-11-28 |
| Prophylactic Anecortave Acetate in Patients With a Retisert Implant anecortave acetate - Uveitis, Posterior, Glaucoma | Phase 1 | Completed | Texas Retina Associates | 12 | 2006-09-01 | 2012-06-05 |
| Anecortave Acetate Risk Reduction Trial (AART) Anecortave Acetate Sterile Suspension, 30 mg/mL, Anecortave Acetate Sterile Suspension, 60 mg/mL, Anecortave Acetate Vehicle - AMD | Phase 3 | Terminated | Alcon Research | 36 | 2006-09-01 | 2012-11-28 |
| Anecortave Acetate in Patients With Open-angle Glaucoma Anecortave Acetate Sterile Suspension, 6 mg/mL, Anecortave Acetate Sterile Suspension, 30 mg/mL, Anecortave Acetate Sterile Suspension, 60 mg/mL - Open-angle Glaucoma | Phase 2 | Completed | Alcon Research | 86 | 2006-03-01 | 2012-11-28 |
| Anecortave Acetate for Treatment of Steroid Induced Intraocular Pressure (IOP) Elevation Anecortave Acetate Sterile Suspension, 6 mg/mL, Anecortave Acetate Suspension Depot, 30 mg/mL, Anecortave Acetate Sterile Suspension, 60 mg/mL - Eye Diseases | Phase 2 | Completed | Alcon Research | 70 | 2005-12-01 | 2012-11-28 |
| Anecortave Acetate Risk-Reduction Trial (AART) Anecortave Acetate Sterile Suspension, 30 mg/mL, Anecortave Acetate Sterile Suspension, 60 mg/ML, Anecortave Acetate Vehicle - AMD | Phase 3 | Terminated | Alcon Research | 24 | 2005-05-01 | 2012-11-28 |
| Anecortave Acetate in Patients With Exudative Age-related Macular Degeneration (AMD) Anecortave Acetate Sterile Suspension, 30 mg/mL, Anecortave Acetate Sterile Suspension, 60 mg/mL, Anecortave Acetate Vehicle - Macular Degeneration | Phase 3 | Completed | Alcon Research | 240 | 2005-03-01 | 2012-11-28 |
| Treatment of Radiation Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg) Anecortave Acetate - Eye Injuries | Phase 2 | Terminated | Manhattan Eye, Ear & Throat Hospital | 2 | 2004-04-01 | 2007-06-21 |
| Anecortave Acetate Risk-Reduction Trial (AART) Anecortave Acetate (AL-3789) sterile suspension, 15 mg or 30 mg, Anecortave Acetate Vehicle - Dry AMD | Phase 3 | Terminated | Alcon Research | 2596 | 2004-03-01 | 2012-11-28 |
| Open-Label Posterior Juxtascleral Injections of Anecortave Acetate 15mg Dose for Long Term Use in Patients With AMD Anecortave Acetate (AL-3789) Sterile Suspension, 30 mg/mL - Macular Degeneration | Phase 3 | Terminated | Alcon Research | 111 | 2003-06-01 | 2013-09-16 |
| Treatment of Conditions With Open Label-Anecortave Acetate Sterile Suspension ( 15mg.) Where Lesions do Not Meet Acceptable Criteria for Standard Care. Anecortave Acetate - Age-Related Macular Degenerations., Subfoveal Neovascularization. | Phase 2 | Completed | Manhattan Eye, Ear & Throat Hospital | 5 | 2003-05-01 | 2007-05-07 |
| An Evaluation of Safety and Efficacy of Anecortave Acetate Versus Placebo in Patients With Subfoveal CNV Due to Exudative AMD anecortave acetate - Macular Degeneration, Maculopathy, Age-Related | Phase 3 | Completed | Alcon Research | 2003-03-01 | 2012-11-29 | |
| Treatment of Patients With Age-Related Macular Degeneration With Anecortave Acetate Anecortave Acetate - Macular Degeneration | No longer available | University of Iowa | 2003-01-01 | 2010-01-15 | ||
| Phase 3 Study to Evaluate Anecortave Acetate vs. Visudyne for the Treatment of the Wet Form of AMD Anecortave Acetate 15 mg sterile suspension, Photodynamic Therapy (PDT) - Macular Degeneration | Phase 3 | Completed | Alcon Research | 530 | 2002-06-01 | 2014-07-01 |
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Macular Degeneration (8) · Glaucoma, Open-Angle (5) · Glaucoma (3) · Retinal Vein Occlusion (2) · Communicable Diseases (1) · Corneal Diseases (1) · Diabetic Retinopathy (1) · Eye Diseases (1) · Eye Injuries (1) · Ocular Hypertension (1) · Retinal Telangiectasis (1) · Uveitis (1) · Uveitis, Posterior (1)
Alcon Research (16) · Manhattan Eye, Ear & Throat Hospital (8) · Cornea Research Foundation of America (1) · Texas Retina Associates (1) · University of Iowa (1)
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Lawrence A. Yannuzzi, MD (6) · Terry Wiernas, PhD (3) · Patricia Zilliox (2) · Theresa Landry (2) · David G Callanan, MD (1) · Edwin M Stone, MD, PhD (1) · Francis W. Price, Jr., MD (1) · Jason S Slakter, MD (1) · Jason S. Slakter, MD (1) · Patricia Zilliox, Ph.D. (1) · Stephen R. Russell, MD (1) · Theresa Landry, Ph.D. (1)
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