20 completed, 2 terminated, 2 withdrawn. 13 Phase 4, 7 Phase 3, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 10, Terminated 2, Withdrawn 1 |
| Phase 3 | 7 | Completed 6, Withdrawn 1 |
| Not applicable | 1 | Completed 1 |
Follow Duotrav: new trials by email Literature Review of Duotrav trials Research Report on Duotrav
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV® Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension, Brinzolamide/brimonidine vehicle, Travoprost 0.004%/timolol 0.5% solution - Open-angle Glaucoma, Ocular Hypertension | Phase 4 | Terminated | Alcon Research | 173 | 2016-06-24 | 2019-05-29 |
| Choroidal Thickness and Its Correlations With Ocular Parameters in Primary Open-angle Glaucoma Brimonidine Tartrate, Dorzolamide (as Dorzolamide Hydrochloride) 20 Mg/mL and Timolol (as Timolol Maleate) 5 Mg/mL Eye Drops, Brinzolamide/Timolol 10 MG/1 ML-5 MG/1 ML Ophthalmic Suspension - Glaucoma, Open-Angle | Phase 4 | Completed | Afyon Kocatepe University Hospital | 96 | 2014-01-01 | 2019-05-29 |
| Efficacy of Travoprost/Timolol for Uncontrolled Intraocular Pressure Beta-blocker monotherapy, Travoprost 0.004% / timolol 0.5% fixed combination ophthalmic solution - Open Angle Glaucoma, Ocular Hypertension | Phase 4 | Completed | Alcon Research | 157 | 2013-12-01 | 2016-08-08 |
| Assessing the Efficacy of DuoTrav as a Replacement Therapy in Glaucoma Patients in Russia Travoprost 0.004%/Timolol 0.5% Fixed Combination (DuoTrav) - Glaucoma, Ocular Hypertension | Phase 4 | Withdrawn | Alcon Research | 2013-02-01 | 2013-02-07 | |
| Efficacy of Changing to DuoTrav® (Travoprost 0.004%/Timolol 0.5% BAK-Free Fixed Combination) From Prior Therapy Travoprost/Timolol Maleate BAK-Free Fixed Combination - Glaucoma | Phase 4 | Terminated | Alcon Research | 37 | 2012-06-01 | 2014-12-03 |
| Safety and Efficacy of LUMIGAN® RC Versus DuoTrav® in Patients Who Require Further Intraocular Pressure (IOP) Reduction travoprost ophthalmic solution 0.004%, travoprost 0.004% / timolol 0.5% combination ophthalmic solution, Bimatoprost ophthalmic solution 0.01% - Glaucoma, Open-Angle, Ocular Hypertension | Phase 4 | Completed | Allergan | 135 | 2011-12-01 | 2014-08-15 |
| Efficacy of Changing to DUOTRAV® From Prior Therapy Travoprost 0.004%+Timolol 0.5% ophthalmic solution - Open-Angle Glaucoma, Ocular Hypertension | Phase 4 | Completed | Alcon Research | 60 | 2011-08-01 | 2014-02-10 |
| Safety and Efficacy of Changing to DuoTrav in Patients Uncontrolled on Timolol Travoprost 0.004%/timolol maleate 0.5% fixed combination - Glaucoma | Phase 4 | Completed | Alcon Research | 50 | 2011-02-01 | 2013-07-08 |
| Bimatoprost/Timolol Versus Travoprost/Timolol Ganfort, Duotrav - Glaucoma | Not applicable | Completed | Kasr El Aini Hospital | 80 | 2011-01-01 | 2012-03-02 |
| Safety and Efficacy of Changing to DuoTrav From Prior Therapy Travoprost 0.004%/Timolol 0.5% Fixed Combination eye drops solution (Duotrav®) - Glaucoma | Phase 4 | Completed | Alcon Research | 105 | 2010-10-01 | 2016-11-21 |
| A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Ganfort, Duotrav - Ocular Hypertension, Primary Open Angle Glaucoma | Phase 3 | Completed | Ministry of Health, Malaysia | 42 | 2010-08-01 | 2011-07-08 |
| Real World Data Study Assessing The Persistency Of Xalacom And The Other Fixed Dose Combination Products, Duotrav And Ganfort, In The United Kingdom XALACOM, Duotrav, Ganfort - Glaucoma, Ocular Hypertension | Completed | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2015 | 2010-02-01 | 2021-02-02 | |
| Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertension Travoprost/Timolol Maleate Fixed Combination solution - Open-angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | Alcon Research | 155 | 2009-07-01 | 2014-07-18 |
| Safety and Efficacy Study of DuoTrav APS Versus DuoTrav DuoTrav APS, DuoTrav - Open-angle Glaucoma, Ocular Hypertension | Phase 3 | Withdrawn | Alcon Research | 2009-03-01 | 2012-01-18 | |
| DuoTrav® Eye Drops As Replacement Therapy Program DuoTrav - Open-angle Glaucoma, Ocular Hypertension | Phase 4 | Completed | Alcon Research | 128 | 2009-02-01 | 2012-09-20 |
| A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma DuoTrav (travoprost-timolol ophthalmic drops), Xalacom (latanoprost-timolol ophthalmic drops) - Open-Angle Glaucoma, Ocular Hypertension | Phase 4 | Completed | Ophthalmic Consultants Centres, Canada | 54 | 2009-01-01 | 2015-04-21 |
| Safety and Efficacy of Travoprost/Timolol BAC-free Travoprost 0.004%/Timolol 0.5% BAC-free ophthalmic solution, Travoprost 0.004%/Timolol 0.5% ophthalmic solution - Open-Angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | Alcon Research | 87 | 2008-06-01 | 2014-07-16 |
| A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension Travoprost 0.004%/Timolol 0.5% BAC-free ophthalmic solution, Travoprost 0.004%/Timolol 0.5% ophthalmic solution - Open-Angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | Alcon Research | 301 | 2008-05-01 | 2014-07-16 |
| Glaucoma Adherence Study, Spain Travoprost 0.004%/timolol 0.05% fixed combination eye drops (DuoTrav), Travalert Dosing Aid - Ocular Hypertension, Primary Open Angle Glaucoma | Completed | Alcon Research | 55 | 2008-05-01 | 2012-05-31 | |
| Glaucoma Adherence Study Travoprost 0.004%/timolol 0.05% fixed combination eye drops (DuoTrav), Travalert Dosing Aid - Ocular Hypertension, Primary Open Angle Glaucoma | Completed | Alcon Research | 55 | 2008-05-01 | 2012-05-31 |
Showing 20 of 24. Sign in to see all of them.
Ocular Hypertension (20) · Glaucoma, Open-Angle (18) · Glaucoma (14) · Patient Compliance (3) · Hypertension (2)
Alcon Research (18) · Afyon Kocatepe University Hospital (1) · Allergan (1) · Kasr El Aini Hospital (1) · Ministry of Health, Malaysia (1) · Ophthalmic Consultants Centres, Canada (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1)
United States (3) · Canada (2) · Germany (2) · Spain (2) · Brazil (1) · China (1) · Egypt (1) · France (1) · Italy (1) · Japan (1) · Malaysia (1) · Netherlands (1) · United Kingdom (1)
Abayomi Ogundele, PharmD (3) · Pamela Smith, B.S. (2) · Anna Grau (1) · David B Yan, MD (1) · Dr Francisco M. Honrubia (1) · Mark C Jasek (1) · Navroop Gill, OD (1) · Severine Durier, Pharm.D (1) · Tamer A Macky, MD FRCS (1) · Theresa Landry (1) · Theresa Landry, Ph.D (1)
PMID 11589866, PMID 14736774, PMID 14996520, PMID 17415690, PMID 18826749, PMID 20505839, PMID 21773673, PMID 2788589, PMID 28239491, PMID 9098273
2016 (1)