3 completed, 3 recruiting, 1 not yet recruiting. 7 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 3, Recruiting 3, Not yet recruiting 1 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
Follow Nephrotoxicity: new trials by email Literature Review of Nephrotoxicity trials Research Report on Nephrotoxicity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Renoprotective Role of Vitamin C and Coenzyme Q10 in Nephrotoxicity Vitamin C, Coenzyme Q 10 - Nephrotoxicity | Phase 2 / Phase 3 | Not yet recruiting | Ain Shams University | 75 | 2026-04-20 | 2026-03-17 |
| Alpha-Lipoic Acid in Mitigating Cisplatin-Induced Nephrotoxicity Alpha-Lipoic Acid (ALA) - Cisplatin Nephrotoxicity, Nephrotoxicity | Phase 2 | Recruiting | Minia University | 50 | 2026-03-10 | 2026-05-04 |
| L-Carnitine Protective Effect in Nephrotoxicity L-Carnitine Tartrate, Placebo - Nephrotoxicity | Phase 2 | Recruiting | Tanta University | 46 | 2025-08-10 | 2025-08-12 |
| Efficacy and Safety of N-Acetylcysteine Versus Alpha-Lipoic Acid in Colistin-Induced Nephrotoxicity Addition of sachets of N-acetyl cysteine 1200 mg twice/day to the maintenance dose of colistin, Addition of Alpha-lipoic acid 600mg twice daily to the maintenance dose of colistin - Nephrotoxicity | Phase 2 / Phase 3 | Completed | Ain Shams University | 180 | 2024-11-01 | 2026-02-17 |
| Effect of Huaier Granule on Nephrotoxicity Associated With Targeted Therapy for Advanced Hepatobiliary Malignancies. Huaier Granule, VEGFR-TKIs - Nephrotoxicity | Phase 2 | Completed | Fudan University | 76 | 2023-01-03 | 2026-02-09 |
| Treatment of Radiation and Cisplatin Induced Toxicities with Tempol Tempol, Placebo Solution - Mucositis, Nephrotoxicity | Phase 2 | Recruiting | Matrix Biomed, Inc. | 120 | 2019-05-13 | 2024-11-20 |
| Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy Pantoprazole, High-dose methotrexate infusion duration - Osteosarcoma, Nephrotoxicity | Phase 2 | Completed | Children's Hospital of Philadelphia | 13 | 2013-04-01 | 2020-03-16 |
Neoplasms (2) · Ototoxicity (2) · Mucositis (1) · Osteosarcoma (1) · Proteinuria (1)
Pathological Conditions, Signs and Symptoms (3) · Chemically-Induced Disorders (2) · Drug-Related Side Effects and Adverse Reactions (2) · Ear Diseases (2) · Otorhinolaryngologic Diseases (2) · Pathologic Processes (2) · Radiation Injuries (2) · Wounds and Injuries (2) · Digestive System Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Gastroenteritis (1) · Gastrointestinal Diseases (1) · Male Urogenital Diseases (1) · Mouth Diseases (1)
Ascorbic Acid (1) · Carnitine (1) · Methotrexate (1) · Pantoprazole (1) · Thioctic Acid (1) · coenzyme Q10 (1) · tempol (1)
Ain Shams University (2) · Children's Hospital of Philadelphia (1) · Fudan University (1) · Matrix Biomed, Inc. (1) · Minia University (1) · Tanta University (1)
Egypt (4) · United States (2) · China (1)
Ahmed Mostafa Abd-Elaziz (1) · Amal Kamal Hussein (1) · Asmaa Basem Mohammed (1) · Benji Crane (1) · Dina H El Adly, MSc (1) · Eman Mohamed Sadek (1) · Fatma M Eweda, Master (1) · Frank M Balis, MD (1) · Lamia M El Wakeel, PhD (1) · Lu Wang (1) · Nagwa A Sabri, PHD (1)