122 completed, 24 recruiting, 16 active not recruiting, 16 unknown. 72 Phase 1, 67 Phase 2, 19 Phase 3, 18 Not applicable, 2 Phase 4.
Follow Wilms Tumor: new trials by email Literature Review of Wilms Tumor trials Research Report on Wilms Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Denys-Drash Syndrome and Risk of Post-transplant Lymphoproliferative Disorder Collection of data from the patient's medical file - Denys-Drash Syndrome | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 108 | 2026-06-01 | 2026-05-26 | |
| Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors Becotatug Vedotin - Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Nasopharyngeal Carcinoma | Phase 1 | Recruiting | Sun Yat-sen University | 51 | 2026-05-30 | 2026-05-13 |
| Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors Miltenyi CliniMACS Prodigy ® system, Zoledronic acid - Neuroblastoma, Rhabdomyosarcoma | Phase 1 / Phase 2 | Recruiting | University of Florida | 27 | 2026-02-11 | 2026-06-30 |
| Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE) Selective Antigen Specific dTβRII-expressing T cells combined with B7-H3 CAR T cells - Rhabdomyosarcoma, Ewing Sarcoma | Phase 1 | Recruiting | Children's National Research Institute | 18 | 2026-01-27 | 2026-08-13 |
| Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells SC-CAR.GPC3xIL15.21 CAR T cells - Solid Tumor (Excluding CNS), Liver Cell Carcinoma | Phase 1 | Recruiting | Seattle Children's Hospital | 21 | 2025-12-22 | 2026-02-17 |
| INVESTIGATION OF THE GENETIC ETIOLOGY OF HERNIA SAC DEVELOPMENT IN MALE CHILDREN WITH UNDESCENDED TESTIS AND INGUINAL HERNIA Indirect Inguinal Hernia, Undescended Testis | Active not recruiting | Trakya University | 3 | 2025-09-09 | 2026-05-14 | |
| Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells 21.15.GPC3-CAR T cells - Hepatoblastoma, Hepatocellular Carcinoma | Phase 1 | Recruiting | Baylor College of Medicine | 21 | 2025-06-10 | 2025-11-03 |
| Validation of the EQ-5D-Y-3L and EQ-5D-Y-5L for Paediatric Patients in China Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs) | Not yet recruiting | RenJi Hospital | 360 | 2025-04-01 | 2025-03-13 | |
| Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models Neuroblastoma, Medulloblastoma | Completed | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 1229 | 2025-01-22 | 2026-08-04 | |
| Biomarkers of Resiliency In Childhood Cancer Surgery Wearing Smartwatch, Patient Report Outcomes, Blood Draw - Pediatric Cancer, Neuroblastoma | Recruiting | Mayo Clinic | 40 | 2025-01-15 | 2026-09-14 | |
| Physical Activity and Community EmPOWERment Project PACE Program - Intellectual Disability, Neurodevelopmental Disorders | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 376 | 2025-01-10 | 2026-02-23 |
| Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors CARE T cells - Liver Cancer, Rhabdomyosarcoma | Phase 1 | Recruiting | Baylor College of Medicine | 24 | 2024-05-24 | 2026-08-06 |
| A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors Selinexor - Wilms Tumor, Rhabdoid Tumor | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 45 | 2023-08-01 | 2026-10-23 |
| Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma Dendritic cell vaccination, Atezolizumab, Platinum/pemetrexed based chemotherapy - Malignant Pleural Mesothelioma | Phase 1 / Phase 2 | Recruiting | University Hospital, Antwerp | 15 | 2023-02-24 | 2026-06-05 |
| Nephrogreen. Appearances of Exvivo Renal Tumours Under Near-infrared Indocyanine Green (ICG) - Wilms Tumor, Renal Cancer | Not applicable | Completed | Birmingham Women's and Children's NHS Foundation Trust | 12 | 2023-02-01 | 2025-03-04 |
| Vascular Thrombus Involvement in Nephroblastoma Nephroblastoma With Vena Cava Thrombosis | Completed | Assistance Publique - Hôpitaux de Paris | 72 | 2022-12-12 | 2025-09-12 | |
| A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors Magnetic Resonance-Guided High Intensity Focused Ultrasound, Lyso-thermosensitive Liposomal Doxorubicin - Solid Tumors, Soft Tissue Sarcoma | Phase 2 | Withdrawn | Children's National Research Institute | 2022-11-10 | 2025-01-01 | |
| Metronomic Chemotherapy in Wilms Tumor (MetroWilms-1906) Vincristine, Irinotecan, Temozolomide - Wilms Tumor | Phase 1 / Phase 2 | Recruiting | Centre Oscar Lambret | 28 | 2022-09-14 | 2026-03-18 |
| A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors Cabozantinib - Neuroblastoma, Sarcoma | Phase 2 | Recruiting | Nationwide Children's Hospital | 86 | 2022-07-20 | 2025-08-12 |
| B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) Fludarabine, Cyclophosphamide, MESNA - Pediatric Solid Tumor, Osteosarcoma | Phase 1 | Recruiting | St. Jude Children's Research Hospital | 48 | 2022-07-06 | 2026-05-19 |
Showing 20 of 203. Sign in to see all of them.
Neuroblastoma (112) · Sarcoma (80) · Osteosarcoma (59) · Rhabdomyosarcoma (59) · Sarcoma, Ewing (50) · Kidney Neoplasms (43) · Neoplasms (43) · Lymphoma, Non-Hodgkin (42) · Medulloblastoma (42) · Burkitt Lymphoma (40) · Neuroectodermal Tumors, Primitive, Peripheral (39) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (39) · Recurrence (39) · Testicular Neoplasms (39)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (203) · Female Urogenital Diseases (203) · Female Urogenital Diseases and Pregnancy Complications (203) · Kidney Diseases (203) · Male Urogenital Diseases (203) · Neoplasms by Histologic Type (203) · Neoplasms by Site (203) · Neoplasms, Complex and Mixed (203) · Neoplastic Syndromes, Hereditary (203) · Urogenital Diseases (203) · Urogenital Neoplasms (203) · Urologic Diseases (203) · Genetic Diseases, Inborn (202) · Urologic Neoplasms (202) · Kidney Neoplasms (160)
Cyclophosphamide (16) · Vincristine (16) · Filgrastim (13) · Doxorubicin (12) · Etoposide (12) · Radiotherapy (11) · Carboplatin (10) · Dactinomycin (9) · Magnetic Resonance Spectroscopy (9) · Specimen Handling (9) · X-Rays (9) · Granulocyte Colony-Stimulating Factor (8) · Phantoms, Imaging (8) · Ifosfamide (6) · Melphalan (6)
National Cancer Institute (NCI) (31) · Children's Oncology Group (28) · Fred Hutchinson Cancer Center (10) · Memorial Sloan Kettering Cancer Center (8) · St. Jude Children's Research Hospital (6) · M.D. Anderson Cancer Center (5) · Baylor College of Medicine (4) · Emory University (4) · National Institutes of Health Clinical Center (CC) (4) · Sumitomo Pharma America, Inc. (4) · Children's National Research Institute (3) · City of Hope Medical Center (3) · Masonic Cancer Center, University of Minnesota (3) · Seattle Children's Hospital (3) · AeRang Kim (2)
United States (158) · Canada (22) · Puerto Rico (22) · Australia (21) · France (10) · New Zealand (9) · China (8) · United Kingdom (8) · Switzerland (7) · Germany (6) · Israel (6) · Netherlands (6) · Italy (5) · Belgium (4) · Spain (4)
AeRang Kim, MD, PhD (4) · Brian H. Kushner, MD (3) · David Steffin, MD (3) · Elizabeth A Mullen (3) · AeRang Kim, MD (2) · Andrea Hayes-Jordan, MD (2) · Daniel M. Green, MD (2) · Elizabeth Fox, MD (2) · Elizabeth J. Perlman, MD (2) · Elizabeth Perlman, MD (2) · Holly Meany, MD (2) · James I Geller (2) · Jan DeKraker, MD (2) · Kenneth G. Lucas, MD (2) · Thomas J. Walsh, MD (2)
PMID 31401903, PMID 37933882, PMID 19556464, PMID 25209242, PMID 29343557, PMID 31449468, PMID 38396300, PMID 10463285, PMID 15175957, PMID 15459300, PMID 15542800, PMID 15654272, PMID 15814645, PMID 15868587, PMID 16129848, PMID 16172460, PMID 16234526, PMID 16410127, PMID 16547940, PMID 16710034, PMID 16914576, PMID 17084075, PMID 17539021, PMID 18281544, PMID 18391430, PMID 18811224, PMID 18989885, PMID 19075272, PMID 19208794, PMID 19231157, PMID 19300220, PMID 19430790, PMID 20044751, PMID 20332316, PMID 20460632, PMID 20582946, PMID 21189373, PMID 21319349, PMID 21703848, PMID 22504933, PMID 22952427, PMID 23015404, PMID 23382471, PMID 23441092, PMID 23897077, PMID 24481001, PMID 24761742, PMID 24821309, PMID 24909177, PMID 25118636
U10CA180886 (20), U10CA098543 (12), P30CA033572 (2), P30CA068485 (2), U01CA097452 (2), U10CA081920 (2), UM1CA228823 (2), 2009 (1), 2023 (1), P01CA034936 (1), P30CA006973 (1), P30CA008748 (1), P30CA015083 (1), P30CA016672 (1), P30CA022453 (1)