47 completed, 35 unknown, 16 recruiting, 6 active not recruiting. 116 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 116 | Completed 47, Unknown 35, Recruiting 16, Active not recruiting 6, Not yet recruiting 6, Terminated 4, Enrolling by invitation 2 |
Follow NAFLD: new trials by email Literature Review of NAFLD trials Research Report on NAFLD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RE and Probiotics in MAFLD/NAFLD physical exercise programme, probiotics supplementation, Placebo - NASH, NAFLD | Not applicable | Not yet recruiting | Nicolaus Copernicus University | 180 | 2026-11-10 | 2026-10-21 |
| The Effects of 5-methyltetrahydrofolate Supplementation in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease 5-methyltetrahydrofolate (5-MTHF), placebo group - Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD) | Not applicable | Not yet recruiting | Tabriz University of Medical Sciences | 44 | 2026-09-30 | 2026-07-31 |
| Chrononutrition/ Chronotoxicity Intervention in People With Metabolic-associated Steatotic Liver Disease. Diet-Time-restricted eating (TRE), Lifestyle Management - MASLD, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease | Not applicable | Not yet recruiting | Cyprus University of Technology | 150 | 2026-01-05 | 2025-11-19 |
| Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals Caloric restriction intervention, No intervention - NAFLD | Not applicable | Recruiting | Steno Diabetes Center Copenhagen | 8 | 2026-01-01 | 2026-05-04 |
| Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis Embospheres Microspheres - Obesity, Weight Loss | Not applicable | Not yet recruiting | Keith Pereira, MD: | 8 | 2025-12-01 | 2025-07-28 |
| Evaluation of a New Ultrasound System for the Non-invasive Assessment of Liver Steatosis in MASLD/MASH Patients Liver ultrasound - Metabolic Syndrome X, Fatty Liver | Not applicable | Recruiting | E-Scopics | 120 | 2025-07-24 | 2025-08-15 |
| The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Pectin, Cocoa Powder, Magnetic Resonance Imaging with Contrast - Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD) | Not applicable | Recruiting | University of Nottingham | 45 | 2025-06-10 | 2026-07-29 |
| Hepatic Elastography-Enhanced Lifestyle Modification in MASLD Regular monitoring with transient elastography - Transient Elastography, MASLD | Not applicable | Enrolling by invitation | Mahidol University | 92 | 2025-05-12 | 2025-05-13 |
| Intermittent Fasting, Mediterranean Diet and NAFLD Intermittent Fasting - NAFLD, Obesity | Not applicable | Not yet recruiting | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | 60 | 2025-01-01 | 2024-10-26 |
| Optimizing Noninvasive assessMent Of DysmEtabolic Compensated Advanced Liver Disease extra blood sampling - NASH, NAFLD | Not applicable | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 408 | 2024-12-06 | 2026-09-02 |
| The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD. Encourage using pedometer - Daily Step Count, MASLD | Not applicable | Enrolling by invitation | Mahidol University | 86 | 2024-08-01 | 2025-05-15 |
| Lifestyle Changes in PCOS with OSA and NAFLD diet restriction and exercise, diet restriction - PCOS, NAFLD | Not applicable | Unknown | Cairo University | 40 | 2024-07-05 | 2024-09-19 |
| Effects of Almonds in Glucose-intolerant Adults (AGAMEMNON) Raw whole almonds - PreDiabetes, NAFLD | Not applicable | Unknown | Charite University, Berlin, Germany | 150 | 2024-05-23 | 2024-05-24 |
| Vigorous- Versus Moderate-intensity Exercise to Reduce Liver Fat in Adults With Obesity and NAFLD Usual Care Control Group, Moderate-intensity Exercise Intervention, Vigorous-intensity Exercise Intervention - Obesity, NAFLD | Not applicable | Recruiting | The University of Hong Kong | 330 | 2024-05-23 | 2024-07-09 |
| Effect of Consumption of Millet Diet in Patients With NAFLD jowar based products - NAFLD | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 60 | 2024-05-15 | 2024-05-07 |
| Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD Experimental: Case Group - Tomato-free diet, Experimental: Case group - Diet enriched with tomatoes - NAFLD, IBS | Not applicable | Completed | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | 80 | 2024-05-14 | 2026-04-16 |
| Preoperative Ketogenic Diet for Reduction of Hepatic Steatosis Ketogenic Diet - Liver Steatoses, Liver Metastasis Colon Cancer | Not applicable | Recruiting | Anton Skaro | 124 | 2024-05-01 | 2026-05-19 |
| An Imaging-based Quantitative Biomarker Assay for NAFLD in Children Magnetic Resonance Imaging (MRI), Ultrasound (US) - NAFLD, NASH | Not applicable | Active not recruiting | University of Wisconsin, Madison | 24 | 2024-04-01 | 2025-12-17 |
| Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters. Mediterranean diet and moderate intensity physical exercise (outdoor walking). - NAFLD, Obesity | Not applicable | Completed | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | 36 | 2024-03-19 | 2026-04-20 |
| A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men NAFLD-specific weight loss intervention, Wait-list control - NAFLD | Not applicable | Completed | University of Arizona | 15 | 2024-02-05 | 2025-08-24 |
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Non-alcoholic Fatty Liver Disease (116) · Obesity (31) · Fatty Liver (19) · Metabolic Syndrome (16) · Diabetes Mellitus, Type 2 (11) · Insulin Resistance (8) · Dyslipidemias (6) · Motor Activity (6) · Pediatric Obesity (6) · Weight Loss (6) · Diabetes Mellitus (5) · Overweight (5) · Fibrosis (4) · Hypertension (4) · Inflammation (4)
Digestive System Diseases (116) · Liver Diseases (113) · Fatty Liver (97) · Nutritional and Metabolic Diseases (54) · Pathological Conditions, Signs and Symptoms (48) · Signs and Symptoms (39) · Body Weight (38) · Nutrition Disorders (36) · Overnutrition (36) · Metabolic Diseases (33) · Glucose Metabolism Disorders (31) · Overweight (31) · Endocrine System Diseases (20) · Hyperinsulinism (19) · Diabetes Mellitus (14)
Exercise (7) · Diet Therapy (5) · Diet (4) · Caloric Restriction (3) · Hematologic Tests (3) · Diet, Ketogenic (2) · Diet, Mediterranean (2) · Fatty Acids, Omega-3 (2) · Magnetic Resonance Imaging (2) · Standard of Care (2) · 5-methyltetrahydrofolate (1) · Absorptiometry, Photon (1) · Acupuncture Therapy (1) · Ascorbic Acid (1) · Bariatric Surgery (1)
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis (8) · German Institute of Human Nutrition (5) · Charite University, Berlin, Germany (3) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (3) · University Hospital, Angers (3) · University of Oxford (3) · Ziekenhuis Oost-Limburg (3) · Axcella Health, Inc (2) · Federico II University (2) · General University Hospital, Prague (2) · Hvidovre University Hospital (2) · Mahidol University (2) · University of Bologna (2) · University of Nottingham (2) · Aalborg University Hospital (1)
United States (22) · Italy (14) · Germany (9) · United Kingdom (8) · France (6) · Belgium (4) · Denmark (4) · China (3) · Czechia (3) · Finland (3) · India (3) · Israel (3) · Turkey (Türkiye) (3) · Canada (2) · Hong Kong (2)
Alberto R Osella, MD, PhD (3) · Andreas FH Pfeiffer, Prof. Dr. (2) · Leanne Hodson, PhD (2) · Aase Handberg, Prof MD DMSc (1) · Adam Vasura, MD (1) · Anastasia-Stefania Alexopoulos, MD (1) · Andreana Haley, PhD (1) · Andreas F.H. Pfeiffer, Prof. Dr. med. (1) · Andreas FH Pfeiffer, Prof. Dr. med. (1) · Andriana C Kaliora, PhD (1) · Anton Skaro, MD PhD (1) · Asal Neshatbini Tehrani, PhD (1)
PMID 28346567, PMID 12941756, PMID 15942443, PMID 17327354, PMID 17581899, PMID 17679036, PMID 18796671, PMID 18820647, PMID 18972405, PMID 19444870, PMID 20460906, PMID 21206486, PMID 21618575, PMID 21849603, PMID 22013734, PMID 22367009, PMID 22488764, PMID 22958053, PMID 23266543, PMID 23396737, PMID 23930163, PMID 24187469, PMID 24462005, PMID 25040896, PMID 25145475, PMID 25285192, PMID 25349724, PMID 25580206, PMID 26373167, PMID 26378644, PMID 26493259, PMID 26610348, PMID 26629307, PMID 26707365, PMID 26797718, PMID 26879684, PMID 26929930, PMID 27038645, PMID 27064274, PMID 27155867, PMID 27567998, PMID 27836992, PMID 27917585, PMID 27936024, PMID 28039099, PMID 28049662, PMID 28545937, PMID 28585193, PMID 28879026, PMID 28931850
2019 (1), K23DK131290 (1), P30DK040561 (1), P30DK056336 (1), R01DK135645 (1)