9 completed, 5 recruiting, 5 unknown, 2 active not recruiting. 13 Not applicable, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 4, Recruiting 3, Active not recruiting 2, Enrolling by invitation 2, Terminated 1, Unknown 1 |
| Phase 4 | 3 | Unknown 2, Recruiting 1 |
Follow Multi Vessel Coronary Artery Disease: new trials by email Literature Review of Multi Vessel Coronary Artery Disease trials Research Report on Multi Vessel Coronary Artery Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Impact of DCB-based Versus DES-based Intervention in Patients With MVCAD GENOSS® DCB (Paclitaxel-coated PTCA balloon catheter), Contemporary Drug-Eluting Stents (DES) - Multi Vessel Coronary Artery Disease, Percutaneous Coronary Intervention | Not applicable | Recruiting | Genoss Co., Ltd. | 892 | 2026-09-28 | 2026-10-09 |
| Safety Study of Acellular Tissue Engineered Vessel for Coronary Artery Bypass ATEV with ESS - Coronary Artery Disease, Multi Vessel Coronary Artery Disease | Not applicable | Enrolling by invitation | Vascudyne, Inc. | 20 | 2025-08-28 | 2026-07-29 |
| Medical Management vs Partial Revascularization in Diffuse Multivessel Coronary Artery Disease Partial per cutaneous coronary intervention, Optimal medical therapy (OMT) - Multi Vessel Coronary Artery Disease | Not applicable | Active not recruiting | CH. Pervaiz Elahi Institute of Cardiology, Multan | 140 | 2025-07-16 | 2026-10-08 |
| Practice Change With Drug-coated Balloon in Patients With multiVessel Coronary Artery Disease drug-coated balloon, drug-eluting stent - Coronary Artery Disease, Multi Vessel Coronary Artery Disease | Recruiting | Bon-Kwon Koo | 500 | 2023-09-18 | 2023-10-27 | |
| Multidisciplinary Approach to Reduce Cardiovascular Health Disparities Life and Medication Recommendations - Acute Coronary Syndrome, Multi Vessel Coronary Artery Disease | Unknown | LifeBridge Health | 400 | 2023-02-06 | 2024-11-05 | |
| Revascularization Strategy of Multivessel Disease for Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock Undergoing Veno-arterial Extracorporeal Membrane Oxygenator Culprit lesion only PCI, Immediate multi-vessel PCI - Cardiogenic Shock, Acute Myocardial Infarction | Phase 4 | Recruiting | Samsung Medical Center | 560 | 2022-11-16 | 2024-11-06 |
| Dual Antiplatelet Therapy in Patients With Clopidogrel Resistance Following Off-Pump Coronary Artery Bypass Ticagrelor, Clopidogrel - Multi Vessel Coronary Artery Disease | Phase 4 | Unknown | Yonsei University | 204 | 2022-02-01 | 2021-12-22 |
| PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions PCI with OCT guidance - Multi Vessel Coronary Artery Disease, Non-ST Elevation Myocardial Infarction | Not applicable | Recruiting | Erasmus Medical Center | 609 | 2021-11-18 | 2022-02-09 |
| DYNAMX Bioadaptor ImplanTation for the trEatment of Complex Coronary Lesions DynamX Drug-Eluting Coronary Bioadaptor System - Coronary Artery Disease, Chronic Total Occlusion of Coronary Artery | Not applicable | Completed | Elixir Medical Corporation | 55 | 2021-10-19 | 2026-09-14 |
| Timing of FFR-guided PCI for Non-IRA in NSTEMI and MVD (OPTION-NSTEMI) Staged in-hospital complete revascularization, Immediate complete revascularization - Myocardial Infarction, Acute, Multi-Vessel Coronary Artery Stenosis | Not applicable | Recruiting | Chonnam National University Hospital | 1014 | 2021-09-06 | 2026-07-28 |
| STaged Interventional Strategies for Acute ST-seGment Elevation Myocardial Infarction Patient With Multi-vessel Disease（STAGED） Early staged PCI, Late staged PCI - STEMI, Multi Vessel Coronary Artery Disease | Not applicable | Completed | Xiamen Cardiovascular Hospital, Xiamen University | 1586 | 2021-02-11 | 2025-12-12 |
| Xeltis Coronary Artery Bypass Graft (XABG) First in Human (FIH) CABG - Multi Vessel Coronary Artery Disease | Not applicable | Enrolling by invitation | Xeltis | 20 | 2020-10-22 | 2026-07-29 |
| 'MInimalist' or 'MOre Complete' Strategies for Revascularization in Octogenarians Percutaneous coronary intervention (PCI) - Multi Vessel Coronary Artery Disease, Ischemic Heart Disease | Not applicable | Terminated | Copenhagen University Hospital, Rigshospitalet | 3 | 2020-05-13 | 2024-07-11 |
| Influence of Risk Factors on ISR and Nonintervened Lesions Coronary Artery Disease, Multi Vessel Coronary Artery Disease | Completed | RenJi Hospital | 510 | 2020-01-01 | 2023-09-15 | |
| Allopurinol in Diabetes Mellitus and Multivessel Coronary Artery Disease Allopurinol - Diabetes Mellitus, Ischemic Heart Disease | Phase 4 | Unknown | Tel-Aviv Sourasky Medical Center | 100 | 2018-12-01 | 2018-11-21 |
| Impact of Residual Syntax Score and Syntax Revascularization Index on Outcomes of ACS Patients With Multi-Vessel Disease Residual SYNTAX Score, SYNTAX Revascularization Index - STEMI - ST Elevation Myocardial Infarction, Multi Vessel Coronary Artery Disease | Completed | Assiut University | 149 | 2018-07-01 | 2022-02-22 | |
| The TransCatheter Valve and Vessels Trial FFR-guided PCI and TAVI, CABG and SAVR - Aortic Stenosis, Multi Vessel Coronary Artery Disease | Not applicable | Completed | Maatschap Cardiologie Zwolle | 172 | 2018-05-31 | 2025-01-09 |
| 18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability PET-MRI, Optical Coherence Tomography - Myocardial Infarction, Myocardial Ischemia | Completed | Maastricht University Medical Center | 15 | 2018-03-02 | 2020-02-21 | |
| Culprit Lesions in NSTEMI With Multi Vessel Disease (NSTEMI-CULPRIT) CMR and OCT in NSTEMI patients with MVD - NSTEMI - Non-ST Segment Elevation MI, Multi Vessel Coronary Artery Disease | Unknown | Copenhagen University Hospital, Rigshospitalet | 100 | 2018-01-10 | 2023-03-29 | |
| iFR Guided Multi-vessel Revascularization During Percutaneous Coronary Intervention for Acute Myocardial Infarction iFR, CMR - Acute Myocardial Infarction, Multi Vessel Coronary Artery Disease | Not applicable | Active not recruiting | Radboud University Medical Center | 1146 | 2017-12-21 | 2026-08-14 |
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Coronary Artery Disease (6) · ST Elevation Myocardial Infarction (4) · Acute Coronary Syndrome (3) · Myocardial Ischemia (3) · Non-ST Elevated Myocardial Infarction (3) · Myocardial Infarction (2) · Angina, Stable (1) · Angina, Unstable (1) · Aortic Valve Stenosis (1) · Arteriosclerosis (1) · Atherosclerosis (1) · Cardiovascular Diseases (1) · Coronary Disease (1) · Coronary Stenosis (1) · Diabetes Mellitus (1)
Cardiovascular Diseases (17) · Heart Diseases (17) · Vascular Diseases (17) · Myocardial Ischemia (14) · Infarction (9) · Ischemia (9) · Necrosis (9) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Arterial Occlusive Diseases (7) · Myocardial Infarction (7) · Arteriosclerosis (6) · Coronary Disease (6) · Angina Pectoris (1) · Aortic Valve Disease (1)
Percutaneous Coronary Intervention (3) · Tomography, Optical Coherence (2) · Allopurinol (1) · Clopidogrel (1) · Coronary Artery Bypass (1) · Drug-Eluting Stents (1) · Microvascular Density (1) · Ticagrelor (1) · Transcatheter Aortic Valve Replacement (1)
Copenhagen University Hospital, Rigshospitalet (2) · Abbott Medical Devices (1) · Aesculap AG (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Bon-Kwon Koo (1) · CH. Pervaiz Elahi Institute of Cardiology, Multan (1) · CathWorks Ltd. (1) · Chonnam National University Hospital (1) · Elixir Medical Corporation (1) · Erasmus Medical Center (1) · Genoss Co., Ltd. (1) · LifeBridge Health (1) · Maastricht University Medical Center (1) · Maatschap Cardiologie Zwolle (1)
South Korea (5) · Netherlands (4) · Denmark (3) · Italy (3) · Poland (3) · China (2) · France (2) · Germany (2) · Portugal (2) · Spain (2) · Austria (1) · Belgium (1) · Egypt (1) · Greece (1) · Japan (1)
Bart Meuris, MD (1) · Bon-Kwon Koo, MD, PhD (1) · Francis Joshi, MD,PhD (1) · Jenna Brager, PhD (1) · Jeong Hoon Yang, MD (1) · Khaled M. Elmaghraby, MD (1) · Krzysztof Wrobel, MD PhD (1) · Marco Valgimigli, MD (1) · Massimo Fineschi, MD (1) · Min Chul Kim, MD (1) · Roberto Diletti, MD PhD (1) · Salwa R. Dimitry, MD (1) · Tarek A. Nagib, MD (1)
PMID 30258627, PMID 32000067, PMID 33452200, PMID 33999545, PMID 34420366, PMID 35811565, PMID 36531736, PMID 38309610, PMID 38785084, PMID 39644913, PMID 41159879, PMID 41539383, PMID 42619605