29 completed, 9 unknown, 3 recruiting, 1 active not recruiting. 28 Not applicable, 4 Phase 2, 3 Phase 1, 2 Early Phase 1, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NAC-REPAIR for Post-surgical Pain NAC, NAC 0mg/day (Placebo) - Carpal Tunnel Surgery, Trigger Finger Disorder | Phase 2 | Not yet recruiting | University of Arizona | 80 | 2026-10-15 | 2026-07-17 |
| Morton Toe and Neuromuscular Performance Foot Morphology, Morton Toe | Completed | Giresun University | 47 | 2026-01-10 | 2026-05-14 | |
| Baropodometric Patterns Associated With Metatarsalgia Socks, Standard device, Foot orthoses - Metatarsalgia | Not applicable | Active not recruiting | University of Seville | 180 | 2025-10-01 | 2026-05-04 |
| Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain Resiniferatoxin - Morton's Neuroma | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 3 | 2025-03-13 | 2026-04-13 |
| Sex Differences in Morton's Extension Application on Plantar Pressure Distribution in Different Foot Regions in Female and Male Patients Without Deformities: A Pre-Post Test Study Womens with Morton´s Extension - Healthy | Not applicable | Completed | Mayuben Private Clinic | 50 | 2025-02-28 | 2025-03-06 |
| Randomized Controlled Trial of Custom Foot Orthoses for Chronic Forefoot Pain Podiatric advice, Customized foot orthoses, Sham foot orthoses - Metatarsalgia | Not applicable | Recruiting | Université du Québec à Trois-Rivières | 64 | 2025-02-01 | 2026-02-10 |
| Effects of Prefabricated Foot Orthoses With and Without Metatarsal Pads on Central Metatarsalgia Prefabricated foot orthoses (PFO) with metatarsal pads, Prefabricated foot orthoses (PFO) without metatarsal pads - Metatarsalgia | Not applicable | Completed | Chinese University of Hong Kong | 32 | 2024-01-26 | 2024-07-16 |
| Orthopaedic Simulation of Morton's Extension to Test the Effect on Plantar Pressures of Each Metatarsal Head in Patients Without Deformity: A Pre-post-test Study. Morton extension - Healthy Subjects | Not applicable | Completed | Mayuben Private Clinic | 25 | 2023-05-29 | 2023-06-05 |
| Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation Operation - Medial Malleolus Fracture, Lisfranc Injury | Not applicable | Recruiting | Inion Oy | 125 | 2023-03-07 | 2026-03-13 |
| Radiofrequency Before to Surgical Removal of a Recalcitrant Morton´s Neuroma Radiofrequency - Morton Neuroma, Radriofrequency | Not applicable | Unknown | Universidad de Extremadura | 34 | 2022-10-15 | 2023-05-10 |
| Translation, Validity, and Reliability of the Foot Posture Index (FPI-6) - Turkish Version Foot Posture Index (FPI-6) - Foot Deformities, Pes Planus | Completed | Suleyman Demirel University | 45 | 2022-09-20 | 2022-12-21 | |
| Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma Cryoanalgesia (iovera°®) - Morton's Neuroma, Pain Management | Not applicable | Unknown | Northern California Research Trials, Inc. | 5 | 2022-08-22 | 2022-11-21 |
| Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma Cryoablation, Nerve block - Morton Neuroma | Not applicable | Recruiting | Oregon Health and Science University | 32 | 2022-07-25 | 2025-10-16 |
| A Test of Efficacy and Foot Position Alteration in Patients Wearing Good Feet Arch Supports for the Treatment of Pain Arch supports - Plantar Fasciitis of Both Feet, Metatarsalgia | Completed | Massachusetts General Hospital | 43 | 2022-06-13 | 2025-08-08 | |
| Investigation of the Effect of Custom Made Insoles on Foot Pressure Distribution and Gait Parameters in Patients With Morton's Neuroma Custom made orthosis - Morton Neuroma | Not applicable | Unknown | Acibadem University | 35 | 2022-06-01 | 2022-06-09 |
| Percutaneous Needle Electrolysis on Metatarsalgia Conservatory treatment, Innovate treatment - Metatarsalgia | Not applicable | Unknown | University of Seville | 30 | 2022-03-01 | 2022-11-02 |
| Orthopaedic Treatment in Propulsive Metatarsalgia EVA plantar orthosis, Polypropylene plantar orthosis, Fixtoe device - Metatarsalgia, Treatment | Not applicable | Completed | Universidad Complutense de Madrid | 80 | 2022-01-01 | 2023-02-06 |
| Effectiveness of Specifically Optimized Off-the-counter Foot Orthosis for the Subtle Cavus Foot Specifically optimized off-the-counter foot orthosis (Medical grade foot orthosis), Plain off-the-counter foot orthosis (Medical grade foot orthosis) - Subtle Cavus Foot, Mechanical Foot Pains | Not applicable | Completed | Tan Tock Seng Hospital | 29 | 2021-10-20 | 2023-10-18 |
| Comparison of the Effects of Morton's Neuroma on Foot Pressure Distribution and Gait Parameters in Pes Planus and Pes Cavus Patients Comparison of gait and foot pressure - Morton Neuroma, Pes Planus | Completed | Acibadem University | 40 | 2021-07-01 | 2021-10-26 | |
| US and MRI of the Forefoot: Intermetatarsal Bursitis or Morton's Neuroma MRI with contrast, Ultrasound - Intermetatarsal Bursitis, Morton Neuroma | Not applicable | Enrolling by invitation | Copenhagen University Hospital, Rigshospitalet | 75 | 2021-06-14 | 2024-11-15 |
Showing 20 of 45. Sign in to see all of them.
Morton Neuroma (25) · Flatfoot (3) · Hallux Valgus (3) · Pain (3) · Fasciitis, Plantar (2) · Foot Deformities (2) · Foot Diseases (2) · Foot Injuries (2) · Nerve Compression Syndromes (2) · Talipes Cavus (2) · Agnosia (1) · Ankle Fractures (1) · Ankylosis (1) · Bunion (1)
Joint Diseases (45) · Neurologic Manifestations (45) · Pathological Conditions, Signs and Symptoms (45) · Signs and Symptoms (45) · Musculoskeletal Diseases (44) · Foot Diseases (43) · Pain (42) · Neuralgia (25) · Neuromuscular Diseases (25) · Nervous System Diseases (24) · Peripheral Nervous System Diseases (24) · Foot Deformities, Acquired (6) · Congenital Abnormalities (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5)
Foot Orthoses (3) · Lidocaine (3) · CNTX-4975 (2) · Cryosurgery (2) · Ethanol (2) · Capsaicin (1) · High-Energy Shock Waves (1) · Magnetic Resonance Imaging (1) · Magnetic Resonance Spectroscopy (1) · Methylprednisolone (1) · Methylprednisolone Acetate (1) · Musculoskeletal Manipulations (1) · Nerve Block (1) · Orthopedic Procedures (1) · Physical Therapy Modalities (1)
Centrexion Therapeutics (3) · Acibadem University (2) · Mayuben Private Clinic (2) · Universidad de Extremadura (2) · University of Seville (2) · AlgoRx Pharmaceuticals (1) · AstraZeneca (1) · Axogen Corporation (1) · Brown University (1) · CMC Ambroise Paré (1) · Chinese University of Hong Kong (1) · Complejo Hospitalario Universitario de Granada (1) · Copenhagen University Hospital, Hvidovre (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dundee Podiatry Clinic (1)
United States (14) · Spain (9) · Turkey (Türkiye) (4) · Denmark (3) · France (2) · Taiwan (2) · Brazil (1) · Canada (1) · Finland (1) · Hong Kong (1) · Singapore (1) · Sweden (1) · United Kingdom (1)
Adam S Landsman, DPM, PhD (1) · Andrew J Mannes, M.D. (1) · Bror Jonzon, MD, PhD (1) · Chang Bao-Chi (1) · Christopher Digiovanni, MD (1) · Chuan Guan Ng (1) · Claire Kaufman (1) · David G Cashley, BSc(Hons)Pod (1) · David Spinner, DO (1) · Eric Diamond, D.P.M. (1) · Fung Ting Chan (1) · Jean Paul Foumenteze, Dr (1)
PMID 16045848, PMID 17515235, PMID 21421939, PMID 23636185, PMID 24119776, PMID 27037432, PMID 34205056, PMID 34980055, PMID 3623359, PMID 37835830, PMID 41544006