38 completed, 5 recruiting, 5 unknown, 3 terminated. 52 Phase 1, 25 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 52 | Completed 38, Recruiting 5, Unknown 5, Terminated 3, Withdrawn 1 |
| Phase 2 | 25 | Completed 19, Recruiting 4, Terminated 1, Unknown 1 |
Follow Metabolic Syndrome: new trials by email Literature Review of Metabolic Syndrome trials Research Report on Metabolic Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause Hyperbaric oxygen therapy, Hypoglycemic Drug - Insulin Resistance Syndrome | Phase 1 / Phase 2 | Recruiting | Cairo University | 40 | 2025-01-28 | 2025-02-04 |
| Integrated Traditional Chinese Medicine Day Care Program for Metabolic Syndrome A fiixed combination of Chinese herbal medicine, Laser acupuncture - Obesity, Metabolic Syndrome | Phase 1 / Phase 2 | Recruiting | Chang Gung Memorial Hospital | 200 | 2024-11-20 | 2024-11-25 |
| Effect of 4 Weeks of Oral D. Piger on Safety, Pharmacokinetics and Ethanol Metabolism in Overweight Individuals (2023) D piger, Placebo - Obesity, Metabolic Syndrome | Phase 1 | Unknown | Max Nieuwdorp | 20 | 2024-05-01 | 2024-07-16 |
| The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function Empagliflozin 25 MG, Placebo - Obesity, Metabolic Syndrome | Phase 1 / Phase 2 | Recruiting | Vanderbilt University Medical Center | 74 | 2023-09-06 | 2026-09-01 |
| Effect of Oral 6-bromotryptophan on Safety, Pharmacokinetics and Efficacy in Metabolic Syndrome Individuals 6-BT, Placebo - Metabolic Syndrome, Diabetes Mellitus | Phase 1 / Phase 2 | Unknown | Nordin Hanssen | 36 | 2023-05-04 | 2023-08-22 |
| Strawberries and Risk of Diabetes in Adults Freeze-dried strawberry powder - PreDiabetes, Metabolic Syndrome | Phase 1 | Completed | University of Nevada, Las Vegas | 39 | 2023-01-01 | 2025-05-18 |
| A Study to Explore the PK and PD of INV-202 in Metabolic Syndrome INV-202, Placebo - Metabolic Syndrome | Phase 1 | Completed | Inversago Pharma Inc. | 37 | 2022-03-01 | 2025-03-27 |
| Pharmacodynamics and Pharmacokinetics of 3 New Developed Coated Glucose Beads in 20 Obese Healthy Subjects coated beads glucose (8 g) and caffeine anhydrous, coated beads glucose (8 g), uncoated beads glucose (8 g) and caffeine anhydrous - Metabolic Syndrome, Obesity | Phase 1 | Completed | Aphaia Pharma US LLC | 20 | 2019-10-25 | 2023-02-06 |
| Probiotics and Gut Health Yogurt smoothie with BB-12, Yogurt smoothie - Metabolic Syndrome | Phase 1 / Phase 2 | Recruiting | Penn State University | 40 | 2018-06-29 | 2021-12-14 |
| Infusion of Umbilical Cord Versus Bone Marrow Derived Mesenchymal Stem Cells to Evaluate Cytokine Suppression. UCMSCs, BMMSCs, Placebo - Endothelial Dysfunction, Metabolic Syndrome | Phase 1 / Phase 2 | Terminated | Joshua M Hare | 14 | 2018-04-12 | 2022-11-08 |
| MANP in Hypertension and Metabolic Syndrome MANP - Hypertension, Metabolic Syndrome | Phase 1 | Completed | Mayo Clinic | 22 | 2017-08-18 | 2020-11-13 |
| Evaluation of 3-V Bioscience-2640 to Reduce de Novo Lipogenesis in Subjects With Characteristics of Metabolic Syndrome 3-V Bioscience-2640 - Metabolic Syndrome | Phase 1 / Phase 2 | Completed | University of Missouri-Columbia | 12 | 2017-02-01 | 2025-05-04 |
| Mechanisms of Cerebrovascular Control NOS Inhibition, ET-1 Inhibition, NOS Inhibition Placebo - Metabolic Syndrome X | Phase 1 | Completed | University of Wisconsin, Madison | 59 | 2017-01-31 | 2021-10-18 |
| Metabolic Effects of Angiotensin-(1-7) Angiotensin-(1-7), Saline - Obesity, Insulin Resistance | Phase 1 | Recruiting | Vanderbilt University | 26 | 2016-02-01 | 2026-05-22 |
| Study to Assess Safety, Tolerability and Pharmacokinetics of Treamid in Healthy Volunteers Treamid 5 mg, Treamid 15 mg, Treamid 50 mg - Metabolic Syndrome | Phase 1 | Completed | PHARMENTERPRISES LLC | 20 | 2016-01-25 | 2020-06-17 |
| Acute Effects of Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects Fat challenge breakfast, Fat challenge breakfast+spices, Carbohydrate challenge breakfast - Healthy | Phase 1 / Phase 2 | Completed | Lund University | 12 | 2015-06-01 | 2015-09-22 |
| Safety, Tolerability and Pharmacokinetic Study of MB12066 in Healthy Male Volunteers MB12066 200mg, Placebo - Metabolic Syndrome | Phase 1 | Completed | Yungjin Pharm. Co., Ltd. | 11 | 2015-01-01 | 2017-12-21 |
| Effect of Brazilian Fruits Peel on Metabolic Regulation and Appetite in Healthy Subjects Control drink, Brazilian fruit peel flour, Negative control drink - Healthy | Phase 1 / Phase 2 | Completed | Lund University | 17 | 2014-09-01 | 2016-09-07 |
| Effects of Colchicine in Non-Diabetic Adults With Metabolic Syndrome Colchicine 0.6Mg Cap, Placebo capsules given, Colchicine 0.6Mg Tab - Obesity, Metabolic Disease | Phase 1 / Phase 2 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 77 | 2014-05-31 | 2019-08-13 |
| Acute Dose Response of Korean White Ginseng in Metabolic Syndrome or Type 2 Diabetes 1 gram of White Korean Ginseng, 3 grams of White Korean Ginseng, 6 grams of White Korean Ginseng - Type 2 Diabetes, Metabolic Syndrome | Phase 1 | Completed | Unity Health Toronto | 30 | 2013-05-01 | 2014-04-15 |
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Obesity (20) · Insulin Resistance (12) · Hypertension (9) · Diabetes Mellitus (7) · Inflammation (5) · Diabetes Mellitus, Type 2 (4) · Overweight (4) · Dyslipidemias (3) · Hyperlipidemias (3) · Fatty Liver (2) · Glucose Intolerance (2) · Hypercholesterolemia (2) · Prediabetic State (2) · Aneurysm (1)
Glucose Metabolism Disorders (52) · Hyperinsulinism (52) · Nutritional and Metabolic Diseases (52) · Metabolic Diseases (51) · Insulin Resistance (40) · Pathological Conditions, Signs and Symptoms (28) · Signs and Symptoms (25) · Body Weight (24) · Nutrition Disorders (23) · Overnutrition (23) · Overweight (19) · Endocrine System Diseases (13) · Cardiovascular Diseases (10) · Vascular Diseases (10) · Lipid Metabolism Disorders (8)
Exercise (3) · beta-lapachone (3) · Atorvastatin (2) · Diet (2) · Sodium Chloride (2) · 2,4-thiazolidinedione (1) · 4'-galactooligosaccharide (1) · Acetates (1) · Anastrozole (1) · Asian ginseng (1) · Bloodletting (1) · Calcium Carbonate (1) · Capsules (1) · Carbohydrates (1) · Cholecalciferol (1)
Yungjin Pharm. Co., Ltd. (3) · Lund University (2) · University of Michigan (2) · Vanderbilt University Medical Center (2) · Aga Khan University (1) · Aphaia Pharma US LLC (1) · Bambino Gesù Hospital and Research Institute (1) · Cairo University (1) · Chang Gung Memorial Hospital (1) · Charite University, Berlin, Germany (1) · Clasado (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Fukuoka University (1) · Griffin Hospital (1) · Institut National de la Santé Et de la Recherche Médicale, France (1)
United States (25) · Canada (3) · Netherlands (3) · South Korea (2) · Sweden (2) · United Kingdom (2) · Cameroon (1) · Egypt (1) · France (1) · Germany (1) · Indonesia (1) · Israel (1) · Italy (1) · Japan (1) · Kazakhstan (1)
Kyung-Sang Yu, Professor (2) · Yoghatama Cindya Zanzer, MSc (2) · Alex Calizzano, MD (1) · Alfredo Gamboa, MD (1) · Alka M. Kanaya, MD (1) · Anastassios G Pittas, MD MS (1) · Andreas Michalsen, Prof., M.D. (1) · Arpita Basu, PhD (1) · Carmen Vizman, Doctor (1) · Claude J Jensen, MS (1) · Cyndya Shibao, MD (1) · David L Katz, MD, MPH (1) · Deborah Grady, MD, MPH (1)
PMID 16818482, PMID 18400730, PMID 18491071, PMID 18825363, PMID 19142567, PMID 19487105, PMID 19500003, PMID 19816674, PMID 20551965, PMID 20833991, PMID 21233083, PMID 21714890, PMID 21715514, PMID 21865361, PMID 22140269, PMID 22647517, PMID 22743313, PMID 23220074, PMID 23303873, PMID 23361157, PMID 23593417, PMID 24074360, PMID 24212451, PMID 24328357, PMID 24586256, PMID 25136536, PMID 25341798, PMID 25536669, PMID 25890676, PMID 26486974, PMID 26541392, PMID 27194308, PMID 27581680, PMID 28163748, PMID 28945992, PMID 29574070, PMID 30201848, PMID 30869182, PMID 30888989, PMID 30937899, PMID 31002414, PMID 31630414, PMID 31740368, PMID 32295829, PMID 32574226, PMID 32863171, PMID 33485731, PMID 35695616, PMID 36160410, PMID 38160756
2009 (1), K23HL103976 (1), R01DK065515 (1), R01DK076092 (1), ZIAHD000641-23 (1)