9 completed, 5 terminated, 3 recruiting, 1 active not recruiting. 6 Early Phase 1, 6 Phase 1, 6 Phase 2, 3 Not applicable, 1 Phase 3.
Follow this drug Literature Review of Acetates trials Research Report on Acetates
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety, Efficacy, and Pharmacodynamics of PLL001 in ALS Patients PLL001 or placebo daily subcutaneous injections - Amyotrophic Lateral Sclerosis, ALS | Phase 1 / Phase 2 | Not yet recruiting | PLL TX AUSTRALIA PTY LTD | 153 | 2026-04-08 | 2026-03-19 |
| Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension Angiotensin-(1-7), Saline - Obesity, Hypertension | Early Phase 1 | Recruiting | Milton S. Hershey Medical Center | 52 | 2025-01-23 | 2026-09-24 |
| Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury Angiotensin (1-7), Sterile saline - Traumatic Brain Injury | Phase 1 / Phase 2 | Recruiting | University of Arizona | 90 | 2024-05-28 | 2026-08-11 |
| Angiotensin-(1-7) Cardiovascular Effects in Aging Angiotensin-(1-7), Saline - Aging | Early Phase 1 | Terminated | Milton S. Hershey Medical Center | 4 | 2022-12-09 | 2026-09-24 |
| Exploring Novel Uses of Microbiota Therapy for Managing the Side Effects of Psychiatric Pharmaceutical Interventions Acetate (Apple Cider Vinegar) - Depression, Anxiety | Phase 1 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 10 | 2022-06-01 | 2023-10-05 |
| Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial Carvedilol, Lisinopril, Pravastatin - Breast Carcinoma, Hematopoietic and Lymphoid Cell Neoplasm | Phase 2 | Withdrawn | Mayo Clinic | 2020-09-01 | 2023-05-24 | |
| Erdafitinib and Abiraterone Acetate or Enzalutamide in Treating Patients With Double Negative Prostate Cancer Abiraterone Acetate, Enzalutamide, Erdafitinib - Castration-Resistant Prostate Carcinoma, Double-Negative Prostate Carcinoma | Phase 2 | Terminated | University of Washington | 3 | 2020-04-27 | 2023-09-28 |
| Angiotensin-(1-7) and Energy Expenditure in Human Obesity Angiotensin-(1-7), Saline - Obesity | Early Phase 1 | Completed | Amy Arnold | 27 | 2019-09-26 | 2026-09-24 |
| Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors Incomplete Freund's Adjuvant, Octreotide Acetate, Sargramostim - Lung Atypical Carcinoid Tumor, Lung Typical Carcinoid Tumor | Phase 1 | Completed | Roswell Park Cancer Institute | 19 | 2019-06-17 | 2026-02-06 |
| Angiotensin 1-7 in Obesity Hypertension Angiotensin-(1-7), Saline - Obesity, Hypertension | Early Phase 1 | Terminated | Amy Arnold | 8 | 2019-04-01 | 2024-06-10 |
| Angiotensin-(1-7) in Peripheral Arterial Disease Angiotensin 1-7, Saline - Peripheral Arterial Disease | Early Phase 1 | Terminated | Milton S. Hershey Medical Center | 6 | 2017-09-01 | 2024-05-03 |
| Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure Angiotensin-(1-7), Saline - Autonomic Nervous System Disorders, Pure Autonomic Failure | Early Phase 1 | Terminated | Vanderbilt University Medical Center | 7 | 2016-02-01 | 2021-01-12 |
| Metabolic Effects of Angiotensin-(1-7) Angiotensin-(1-7), Saline - Obesity, Insulin Resistance | Phase 1 | Recruiting | Vanderbilt University | 26 | 2016-02-01 | 2026-05-22 |
| Effects of Acetate and Alcohol on Brain Function acetate, alcohol - Cerebral Blood Flow, Brain Function | Not applicable | Completed | University of Colorado, Denver | 24 | 2015-09-01 | 2021-06-25 |
| Short Chain Fatty Acid Metabolism and Energy Metabolism acetate or placebo infusion - Type 2 Diabetes Mellitus, Obesity | Not applicable | Completed | Maastricht University Medical Center | 10 | 2013-04-01 | 2015-09-15 |
| Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab Doxycycline, Management of Therapy Complications, Placebo - Advanced Malignant Neoplasm, Dermatologic Complication | Phase 2 | Completed | Academic and Community Cancer Research United | 19 | 2012-08-31 | 2020-01-09 |
| Everolimus and Octreotide Acetate With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumors That Cannot Be Removed by Surgery Bevacizumab, Everolimus, Octreotide Acetate - Advanced Pancreatic Neuroendocrine Tumor, Locally Advanced Pancreatic Neuroendocrine Tumor | Phase 2 | Completed | National Cancer Institute (NCI) | 150 | 2010-10-15 | 2022-08-04 |
| Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma Cixutumumab, Everolimus, Laboratory Biomarker Analysis - Gastrin-Producing Neuroendocrine Tumor, Lung Carcinoid Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 27 | 2010-10-01 | 2016-07-15 |
| Study to Evaluate 13 C Isotope Ratio Measurement for Urea Cycle Capacity Assessment sodium [1-13C] acetate - Urea Cycle Disorders | Not applicable | Completed | Cytonet GmbH & Co. KG | 10 | 2009-09-01 | 2010-01-15 |
| Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor Bevacizumab, Laboratory Biomarker Analysis, Octreotide Acetate - Colorectal Neuroendocrine Tumor G1, Gastric Neuroendocrine Tumor G1 | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 427 | 2007-12-01 | 2026-10-01 |
Showing 20 of 21. Sign in to see all of them.
Obesity (5) · Hypertension (4) · Adenoma, Islet Cell (1) · Amyotrophic Lateral Sclerosis (1) · Anxiety Disorders (1) · Atherosclerosis (1) · Autonomic Nervous System Diseases (1) · Body Weight (1) · Brain Injuries, Traumatic (1) · Breast Neoplasms (1) · Carcinoma, Medullary (1) · Carcinoma, Merkel Cell (1) · Depression (1) · Diabetes Mellitus, Type 2 (1) · Glucagonoma (1)
Milton S. Hershey Medical Center (3) · National Cancer Institute (NCI) (3) · Amy Arnold (2) · Academic and Community Cancer Research United (1) · Cytonet GmbH & Co. KG (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Maastricht University Medical Center (1) · Mayo Clinic (1) · PLL TX AUSTRALIA PTY LTD (1) · Roswell Park Cancer Institute (1) · University of Arizona (1) · University of Colorado, Denver (1) · University of Washington (1) · Vanderbilt University (1) · Vanderbilt University Medical Center (1)
United States (16) · Canada (2) · Germany (1) · Netherlands (1)
Amy Arnold, PhD (2) · Amy C Arnold, PhD (2) · Alfredo Gamboa, MD (1) · Aminah Jatoi (1) · Amy C Arnold, Ph.D. (1) · Doris Neuenhofer, MD (1) · Ellen Blaak, Prof. (1) · F. S. Cole, M.D. (1) · Italo Biaggioni, MD (1) · James C Yao (1) · James Yao (1) · Jasmeet Kaur, MD (1) · Joerg Herrmann (1) · Magnotti Louis, MD (1)
PMID 18317237, PMID 18383112, PMID 19647838, PMID 20539253, PMID 22222548, PMID 22337229, PMID 22526637, PMID 23166334, PMID 24657120, PMID 24871971, PMID 25712598, PMID 25900182, PMID 28384065, PMID 31386214
K99HL159272 (1), P30CA015083 (1), P30CA016672 (1), R01HL082747 (1), R01HL170140 (1), U01CA062461 (1), U10CA031946 (1), U10CA032102 (1), U10CA180821 (1), U10CA180888 (1), UL1TR001082 (1)