15 completed, 5 unknown, 3 withdrawn, 2 not yet recruiting. 28 Phase 1, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 28 | Completed 15, Unknown 5, Withdrawn 3, Not yet recruiting 2, Terminated 2, Enrolling by invitation 1 |
| Phase 2 | 11 | Completed 5, Unknown 4, Enrolling by invitation 1, Terminated 1 |
Follow Menstruation Disturbances: new trials by email Literature Review of Menstruation Disturbances trials Research Report on Menstruation Disturbances
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MLS101 Study in PMDD MLS101 psilocybin, Placebo capsules - Premenstrual Dysphoric Disorder ( PMDD), PMDD | Phase 1 | Not yet recruiting | MycoMedica Life Sciences PBC | 32 | 2026-12-01 | 2026-09-14 |
| Vaginal Sildenafil for Primary Dysmenorrhea Sildenafil citrate vaginal suppository - Dysmenorrhea, Menstrual Pain | Phase 1 | Not yet recruiting | Kevin Hellman | 10 | 2026-10-01 | 2026-09-25 |
| A Study to Measure Pharmacokinetic (PK) Concentrations of Gonadotropin-Releasing Hormone Delivered by the OmniPod Pump Lutrepulse - Amenorrhea, Fertility | Phase 1 | Withdrawn | Ferring Pharmaceuticals | 2025-09-12 | 2025-11-14 | |
| Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in Adolescent Females With Type 1 Diabetes Mellitus Dulaglutide - Menstrual Irregularities, Type1 Diabetes Mellitus | Phase 1 / Phase 2 | Enrolling by invitation | Ain Shams University | 50 | 2025-08-04 | 2026-06-05 |
| PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis Sample Collection and Endometrial Biopsy - Menstrual Bleeding, Heavy | Phase 1 / Phase 2 | Unknown | Oregon Health and Science University | 70 | 2023-07-12 | 2024-08-19 |
| An Investigation Into the Efficacy of a Botanical Supplement to Provide Period Relief Pamprin Botanicals, Pamprin Botanicals + Pamprin Menstrual Pain Relief - Menstrual Pain, Premenstrual Syndrome | Phase 1 | Completed | Focus Consumer Healthcare | 100 | 2023-02-08 | 2024-02-29 |
| Quality of Life Outcomes for Ulipristal Acetate and Tranexamic Acid in the Management of Heavy Menstrual Bleeding UPA, TEA, Placebo (for UPA) - Heavy Menstrual Bleeding | Phase 1 | Withdrawn | University of Saskatchewan | 2020-01-01 | 2020-01-28 | |
| Comparison of Metformin and Pioglitazone in Regulating Menstrual Irregularities and Hyperandrogenism TAB METFORMIN, TAB PIOGLITAZONE - Menstrual Irregularities, Hyperandrogenism | Phase 1 / Phase 2 | Unknown | Dow University of Health Sciences | 110 | 2018-06-18 | 2018-11-29 |
| Estradiol and Fear Extinction in Anorexia Nervosa (AN) Estradiol - Anorexia Nervosa | Phase 1 | Withdrawn | Johns Hopkins University | 2016-12-01 | 2018-08-24 | |
| The Effect of Cyclofem® for the Treatment of Irregular Uterine Bleeding in Implant Contraceptive Users Cyclofem - Uterine Bleeding | Phase 1 / Phase 2 | Unknown | Chulalongkorn University | 44 | 2016-08-01 | 2017-08-30 |
| Oral Tranexamic Acid Versus Diosmin for Treatment of Menorrhagia in Women Using Copper IUD Tranexamic Acid, Diosmin - Menorrhagia | Phase 1 / Phase 2 | Unknown | Ain Shams University | 100 | 2015-09-01 | 2015-11-30 |
| Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution KSL 40 mg, OKi® 80 mg - Pain Disorders | Phase 1 | Completed | Dompé Farmaceutici S.p.A | 30 | 2014-11-26 | 2024-04-19 |
| Electroacupuncture for Diminished Ovarian Reserve EA, HRT, DHEA and herb - Irregular Menses | Phase 1 | Completed | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 57 | 2014-01-01 | 2016-10-10 |
| Vaginal Bromocriptine for Treatment of Adenomyosis Vaginal Bromocriptine - Adenomyosis | Phase 1 | Completed | Mayo Clinic | 1 | 2013-03-01 | 2018-01-12 |
| A Phase I/II Study to Evaluate UC1010 Treatment in Premenstrual Dysphoric Disorder (PMDD) UC1010, Placebo - Premenstrual Dysphoric Disorder | Phase 1 / Phase 2 | Completed | Umecrine Mood AB | 146 | 2013-01-01 | 2015-01-21 |
| Turmeric Effect on Reduction of Serum Prolactin and Related Hormonal Change and Adenoma Size in Prolactinoma Patients Curcumin - Hyperprolactinoma | Phase 1 | Unknown | Mashhad University of Medical Sciences | 30 | 2011-07-01 | 2011-11-01 |
| Dose-Finding Study of PDC31 in Patients With Primary Dysmenorrhea PDC31 - Dysmenorrhea | Phase 1 | Completed | PDC Biotech GmbH | 24 | 2010-11-01 | 2012-09-24 |
| Determination of the Lowest, Safe and Effective Dose of Proellex Proellex - Amenorrhea | Phase 1 / Phase 2 | Completed | Repros Therapeutics Inc. | 52 | 2010-08-01 | 2014-07-28 |
| A Feasibility Study Designed to Assess the Efficacy of the ActiLady Device in Adult Female Subjects With Dysmenorrhea Miniature Actilady device active, Miniature Actilady device not active - Dysmenorrhea | Phase 1 | Completed | Hadassah Medical Organization | 24 | 2010-05-01 | 2013-11-13 |
| Study to Evaluate Menses Induction in Women Administered Proellex Placebo, Proellex - Amenorrhea | Phase 1 | Terminated | Repros Therapeutics Inc. | 11 | 2009-02-01 | 2014-08-25 |
Showing 20 of 28. Sign in to see all of them.
Dysmenorrhea (10) · Amenorrhea (6) · Menorrhagia (5) · Premenstrual Syndrome (4) · Depression (2) · Premenstrual Dysphoric Disorder (2) · Uterine Hemorrhage (2) · Adenomyosis (1) · Anemia, Aplastic (1) · Anorexia Nervosa (1) · Anxiety Disorders (1) · Endometriosis (1) · Feeding and Eating Disorders (1) · Headache (1)
Pathologic Processes (28) · Pathological Conditions, Signs and Symptoms (28) · Signs and Symptoms (11) · Neurologic Manifestations (10) · Pain (10) · Pelvic Pain (9) · Urogenital Diseases (9) · Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Genital Diseases (8) · Genital Diseases, Female (7) · Hemorrhage (6) · Uterine Diseases (6) · Mental Disorders (5)
Tranexamic Acid (2) · telapristone acetate (2) · Acupuncture Therapy (1) · Bromocriptine (1) · Contraceptives, Oral (1) · Curcumin (1) · CycloProvera (1) · Dehydroepiandrosterone (1) · Diosmin (1) · Dutasteride (1) · Estradiol (1) · Gonadotropin-Releasing Hormone (1) · Hormone Replacement Therapy (1) · Leuprolide (1) · Metformin (1)
Ain Shams University (2) · Milton S. Hershey Medical Center (2) · National Institute of Mental Health (NIMH) (2) · Repros Therapeutics Inc. (2) · Chulalongkorn University (1) · Dompé Farmaceutici S.p.A (1) · Dow University of Health Sciences (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Ferring Pharmaceuticals (1) · Focus Consumer Healthcare (1) · Guang'anmen Hospital of China Academy of Chinese Medical Sciences (1) · Hadassah Medical Organization (1) · Johns Hopkins University (1) · Kevin Hellman (1) · Mashhad University of Medical Sciences (1)
United States (12) · Croatia (2) · Egypt (2) · Austria (1) · Canada (1) · China (1) · Germany (1) · Iran (1) · Israel (1) · Pakistan (1) · Sweden (1) · Switzerland (1) · Thailand (1) · United Kingdom (1)
Almereau Prollius, MD (1) · Andre van As, M.D., Ph.D (1) · Angela Guarda, MD (1) · Bader F Zuberi, FCPS (1) · Elizabeth Stewart, MD (1) · Frank Tu, MD, MPH (1) · Fredi Kronenberg, PhD (1) · Kimberly A Yonkers, MD (1) · Laura M Sterling, MD (1) · Milko Radicioni, MD (1) · Nitisa Tapanwong, MD (1) · Pamela Stratton, MD (1) · Pedro E Martinez, M.D. (1) · Peter J Schmidt, M.D. (1)
PMID 22617578, PMID 23925396, PMID 25164021, PMID 26733563, PMID 27177929, PMID 28044059, PMID 28786978, PMID 30184299, PMID 34035477, PMID 37523477, PMID 39518671
R21MH062379 (1)