6 recruiting, 5 completed, 4 not yet recruiting, 2 terminated. 4 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Not yet recruiting 2, Completed 1, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Mechanical Circulatory Support: new trials by email Literature Review of Mechanical Circulatory Support trials Research Report on Mechanical Circulatory Support
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TORCH-LATAM-004: Regional Advanced-Therapy Pathways for Adults With Acquired or Structural Heart Disease TORCH Adult Advanced Therapies Pathway (TORCH-AATP) - Advanced Heart Failure, Acquired Heart Disease | Not applicable | Not yet recruiting | CardioVision International Tech, S.A.S. de C.V. | 360 | 2027-03-30 | 2026-10-13 |
| Hong Kong Cardiogenic Shock Initiative Cardiogenic Shock Acute, STEMI - ST Elevation Myocardial Infarction | Not yet recruiting | Prince of Wales Hospital, Shatin, Hong Kong | 320 | 2026-12-01 | 2026-09-16 | |
| Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI) The Supira System, Impella - Coronary Artery Disease, High Risk Percutaneous Coronary Intervention | Not applicable | Recruiting | Supira Medical | 358 | 2026-05-11 | 2026-10-19 |
| OPTIMIZE 5.5 - Optimizing Impella 5.5 Outcomes Through Advanced Data Science Micro-axial flow pump support - Cardiogenic Shock, Mechanical Circulatory Support | Recruiting | Medical University of Vienna | 100 | 2026-05-08 | 2026-06-01 | |
| Cerebral Oximetry, Pulmonary Artery Catheter Parameters and ECMO Flow in Patients Supported With Veno-arterial ECMO Mechanical Circulatory Support | Not yet recruiting | Assiut University | 30 | 2026-04-20 | 2026-04-13 | |
| Palliative Care Intervention to Improve Health Related Quality of Life for Patients on Long-Term LVAD Support Palliative care intervention - Advanced Heart Failure, Mechanical Circulatory Support | Not applicable | Not yet recruiting | Medstar Health Research Institute | 90 | 2026-03-01 | 2026-03-03 |
| Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock Cardiogenic Shock Acute, Bypass, Cardiopulmonary | Recruiting | Centre Hospitalier Universitaire, Amiens | 2500 | 2025-10-20 | 2026-01-21 | |
| Hyperoxia vs Normoxia During Cardiopulmonary Bypass Hyperoxia group, Normoxia group (control) - AKI, Renal Replacement Therapy | Not applicable | Completed | University of Padova | 104 | 2025-07-01 | 2026-04-03 |
| Platelet Function and Impella Support Analysis of platelet function - Cardiogenic Shock, Cardiac Arrest | Completed | Università Vita-Salute San Raffaele | 30 | 2025-02-24 | 2026-05-05 | |
| Clinical Outcomes of Contemporary IMPELLA Devices in Cardiogenic Shock and High-risk Percutaneous Coronary Intervention Impella implantation - Cardiogenic Shock, PCI Patients | Unknown | A.O.U. Città della Salute e della Scienza | 700 | 2024-10-10 | 2024-11-15 | |
| The Usefulness of Myocardial Work IndeX in ExtraCorporeal Membrane Oxygenation Patients Echocardiography, Mechanical Circulatory Support | Unknown | Semmelweis University Heart and Vascular Center | 100 | 2024-06-01 | 2024-04-18 | |
| BRAIN-HEART Ultrasound Study Normative Values for Transcranial Doppler Based Cerebral Blood Flow Assessment Mechanical Circulatory Support | Terminated | Wake Forest University Health Sciences | 6 | 2024-05-22 | 2026-04-02 | |
| LVAD Index and Clinical Outcomes in Continuous-Flow LVAD Patients HeartWare Ventricular Assist Device, HeartMate 3 Left Ventricular Assist Device - End-stage Heart Failure, Left Ventricular Assist Device | Completed | Gaziantep City Hospital | 34 | 2022-10-01 | 2026-06-08 | |
| Cell Therapy and Myocardial Recovery in Heart Failure Patients Undergoing Left Ventricular Assist Device Support CD34+ stem cell therapy - Heart Failure, Mechanical Circulatory Support | Phase 2 | Recruiting | University Medical Centre Ljubljana | 10 | 2022-05-01 | 2026-01-26 |
| Evaluation of Platelet Therapy Response in Left Ventricular Assist Device Patients VerifyNow antiplatelet therapy response test - End-stage Heart Failure, Cardiomyopathies | Completed | Medical University of Vienna | 24 | 2021-12-06 | 2023-11-30 | |
| Cardiac Output in Heart Failure Patients With Mechanical Pumps preload challenge, afterload challenge, contractility assessment - Heart Failure, Systolic, Mechanical Circulatory Support | Terminated | University of Colorado, Denver | 7 | 2021-06-08 | 2023-05-19 | |
| Noninvasive Cardiovascular Diagnosis of Patients With Fully Magnetically Levitated Blood Pumps Routinely performed echo, ECG and hemodynamic monitoring - End-stage Heart Failure, Cardiomyopathies | Recruiting | Thomas Schlöglhofer, PhD, MSc | 60 | 2020-07-09 | 2026-05-08 | |
| Application of Emergent Peripheral Mechanical Circulatory Support in Transcatheter Aortic Valve Replacement for 6 Patients mechanical circulatory support - Transcatheter Aortic Valve Replacement, Mechanical Circulatory Support | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 6 | 2013-03-01 | 2020-07-09 | |
| Product Surveillance Registry Cardiac Rhythm Disorders, Urological Disorders | Recruiting | Medtronic | 100000 | 2012-01-01 | 2026-10-20 |
Shock, Cardiogenic (6) · Cardiomyopathies (2) · Coronary Artery Disease (2) · Heart Failure (2) · Arrhythmias, Cardiac (1) · Cardiovascular Diseases (1) · Digestive System Diseases (1) · Heart Arrest (1) · Heart Failure, Systolic (1) · Hemorrhage (1) · Hyperoxia (1) · Intracranial Aneurysm (1) · Myocardial Infarction (1) · Nervous System Diseases (1) · Renal Insufficiency (1)
Heart Diseases (13) · Cardiovascular Diseases (12) · Myocardial Ischemia (8) · Vascular Diseases (8) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Infarction (6) · Ischemia (6) · Necrosis (6) · Shock (6) · Myocardial Infarction (5) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Coronary Disease (2) · Aneurysm (1)
Electrocardiography (1) · Hemodynamic Monitoring (1)
Medical University of Vienna (2) · A.O.U. Città della Salute e della Scienza (1) · Assiut University (1) · CardioVision International Tech, S.A.S. de C.V. (1) · Centre Hospitalier Universitaire, Amiens (1) · Gaziantep City Hospital (1) · Medstar Health Research Institute (1) · Medtronic (1) · Prince of Wales Hospital, Shatin, Hong Kong (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Semmelweis University Heart and Vascular Center (1) · Supira Medical (1) · Thomas Schlöglhofer, PhD, MSc (1) · University Medical Centre Ljubljana (1) · University of Colorado, Denver (1)
United States (5) · Austria (4) · Italy (4) · China (2) · France (2) · Hong Kong (2) · Hungary (2) · Argentina (1) · Australia (1) · Belgium (1) · Brazil (1) · Canada (1) · Colombia (1) · Czechia (1) · Denmark (1)
Aarti Sarwal, MD (1) · Ashish Khanna, MD (1) · Bojan Vrtovec, MD, PhD (1) · Connor O'Brien (1) · Filippo Consolo, PhD (1) · John Gaillard, MD (1) · Mara Scandroglio, MD (1) · Richa Gupta, MD (1)
PMID 31567325, PMID 32009263, PMID 32763431, PMID 35925831, PMID 36579406, PMID 40758483, PMID 42239929, PMID 42448174