6 completed, 3 recruiting. 9 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 6, Recruiting 3 |
| Phase 1 | 2 | Recruiting 2 |
Follow Lupus: new trials by email Literature Review of Lupus trials Research Report on Lupus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis Mosunetuzumab - Lupus, Systemic Lupus Erythematosus | Phase 2 | Recruiting | Hoffmann-La Roche | 30 | 2026-05-25 | 2026-10-19 |
| CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus CART19 - SLE, Systemic Lupus Erythematosus (SLE) | Phase 1 / Phase 2 | Recruiting | Children's Hospital of Philadelphia | 24 | 2025-05-06 | 2026-09-24 |
| Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders Tafasitamab, Fludarabine phosphate, Cyclophosphamide - Autoimmune Disorders, Systemic Sclerosis | Phase 1 / Phase 2 | Recruiting | M.D. Anderson Cancer Center | 47 | 2024-07-31 | 2026-11-03 |
| JBT-101 in Systemic Lupus Erythematosus (SLE) JBT-101, Placebo - Systemic Lupus Erythematosus, SLE | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 109 | 2017-12-21 | 2026-05-06 |
| Safety and Efficacy Study of a Biologic to Treat Systemic Lupus Erythematosus BMS-931699, Placebo matching BMS-931699 - Lupus | Phase 2 | Completed | Bristol-Myers Squibb | 730 | 2014-11-13 | 2019-10-07 |
| Vitamin D3 in Systemic Lupus Erythematosus Vitamin D3, Vitamin D3 placebo - Systemic Lupus Erythematosus, SLE | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 57 | 2008-11-01 | 2017-04-26 |
| A Study to Evaluate Safety and Tolerability of Subcutaneous Doses of MEDI-545 in Subjects With Lupus MEDI-545, Placebo - Lupus Erythematosus, Systemic, Lupus | Phase 2 | Completed | MedImmune LLC | 87 | 2008-07-01 | 2016-08-09 |
| Improving Quality of Life for African American Female Adolescents With Lupus Coping skills and cognitive restructuring techniques, Educational training - Lupus | Phase 2 | Completed | Medical University of South Carolina | 120 | 2004-04-01 | 2018-05-09 |
| Prevention of Atherosclerosis and Heart Disease in Patients With Systemic Lupus Erythematosis (SLE) pravastatin, aspirin, ramipril - Systemic Lupus Erythematosus, Lupus | Phase 2 | Completed | Brigham and Women's Hospital | 150 | 2003-03-01 | 2013-12-24 |
Lupus Erythematosus, Systemic (7) · Lupus Nephritis (3) · Autoimmune Diseases (1) · Bronchiolitis Obliterans Syndrome (1) · Graft vs Host Disease (1) · Musculoskeletal Diseases (1) · Scleroderma, Systemic (1) · Vitamin D Deficiency (1)
Connective Tissue Diseases (7) · Immune System Diseases (7) · Skin and Connective Tissue Diseases (7) · Autoimmune Diseases (6) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Glomerulonephritis (3) · Kidney Diseases (3) · Male Urogenital Diseases (3) · Nephritis (3) · Urogenital Diseases (3) · Urologic Diseases (3) · Avitaminosis (1) · Bronchial Diseases (1) · Bronchiolitis (1)
Aspirin (1) · CTL019 chimeric antigen receptor (1) · Cholecalciferol (1) · Coping Skills (1) · Cyclophosphamide (1) · Folic Acid (1) · Pravastatin (1) · Ramipril (1) · Training Support (1) · Vitamin B 12 (1) · anabasum (1) · fludarabine phosphate (1) · lenabasum (1) · lulizumab pegol (1) · sifalimumab (1)
National Institute of Allergy and Infectious Diseases (NIAID) (2) · Brigham and Women's Hospital (1) · Bristol-Myers Squibb (1) · Children's Hospital of Philadelphia (1) · Hoffmann-La Roche (1) · M.D. Anderson Cancer Center (1) · MedImmune LLC (1) · Medical University of South Carolina (1)
United States (8) · Argentina (2) · Brazil (2) · Colombia (2) · Italy (2) · Mexico (2) · South Africa (2) · Canada (1) · Chile (1) · France (1) · Germany (1) · Hungary (1) · Japan (1) · Lebanon (1) · Netherlands (1)
Caitlin Elgarten, MD (1) · Chitra Hosing, MD (1) · Cynthia Aranow, MD (1) · Diane Kamen, MD (1) · Matthew H. Liang, MD, MPH (1) · Meggan Mackay, M.D., M.S. (1) · Robert B. Zurier, M.D. (1) · Ronald T. Brown, PhD (1) · Warren Greth, M.D. (1)
PMID 16208639, PMID 21798883, PMID 25777546, PMID 33687069, PMID 42309556
2014 (1), P60AR047782 (1), P60AR049459 (1), UM1AI110494 (1)