8 completed. 4 Phase 1, 4 Phase 2.
By phase and status
Follow sifalimumab: new trials by email Literature Review of sifalimumab trials Research Report on sifalimumab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
A Study to Evaluate the Efficacy and Safety of Sifalimumab in Adults With Systemic Lupus Erythematosus
Sifalimumab 200 mg, Sifalimumab 600 mg, Sifalimumab 1,200 mg - Systemic Lupus Erythematosus | Phase 2 | Completed | MedImmune LLC | 834 | 2011-03-31 | 2018-04-19 |
A Study to Evaluate the Long-Term Safety of MEDI-545 in Adult Participants With Systemic Lupus Erythematosus or Myositis
Sifalimumab - Systemic Lupus Erythematosus | Phase 2 | Completed | MedImmune LLC | 118 | 2010-08-01 | 2016-10-27 |
A Study to Evaluate Safety and Tolerability of IV or SC Dose of MEDI-545 in Patients With Systemic Lupus Erythematosus.
MEDI-545, MEDI-545 600 - Systemic Lupus Erythematosus | Phase 2 | Completed | AstraZeneca | 30 | 2009-11-25 | 2018-11-19 |
A Study to Evaluate Safety and Tolerability of Subcutaneous Doses of MEDI-545 in Subjects With Lupus
MEDI-545, Placebo - Lupus Erythematosus, Systemic, Lupus | Phase 2 | Completed | MedImmune LLC | 87 | 2008-07-01 | 2016-08-09 |
A Study to Evaluate Safety of Multi-Dose MEDI-545 in Adult Patients With Dermatomyositis or Polymyositis
MEDI-545, Placebo - DERMATOMYOSITIS OR POLYMYOSITIS | Phase 1 | Completed | MedImmune LLC | 51 | 2008-04-01 | 2012-05-28 |
A Study to Evaluate the Safety and Tolerability of Multiple Intravenous Doses of MEDI 545 in Patients With Systemic Lupus Erythematosus
MEDI 545, Placebo - Lupus | Phase 1 | Completed | MedImmune LLC | 183 | 2007-06-01 | 2012-07-11 |
A Multicenter Study to Evaluate the Safety and Tolerability of Single-Dose for MEDI-545
MEDI 545, Placebo - Chronic Plaque Psoriasis | Phase 1 | Completed | MedImmune LLC | 40 | 2007-02-01 | 2011-11-17 |
Safety and Tolerability of MEDI-545 in Patients Who Have Systemic Lupus Erythematosus (SLE)
MEDI-545, MEDI 545 - Lupus | Phase 1 | Completed | MedImmune LLC | 45 | 2006-03-01 | 2007-12-18 |
Conditions studied
Lupus Erythematosus, Systemic (4) · Autoimmune Diseases (1) · Dermatomyositis (1) · Immune System Diseases (1)
Sponsors
MedImmune LLC (7) · AstraZeneca (1)
Countries
United States (6) · Canada (4) · Brazil (3) · Chile (3) · Argentina (2) · Bulgaria (1) · France (1) · Germany (1) · Hungary (1) · India (1) · Italy (1) · Jamaica (1) · Japan (1) · Mexico (1) · Netherlands (1)
Top investigators
Barbara White, M.D. (2) · Warren Greth, M.D. (2) · Dominique Ethgen, M.D. (1) · Gabor Illei, MD (1) · Jerry Green (1) · Tsutomu Takeuchi (1) · Yoshiya Tanaka (1)
Results publications
PMID 21798883, PMID 33687069, PMID 19479852, PMID 23400715, PMID 23434567, PMID 23754736, PMID 31660791