18 completed, 4 recruiting, 4 unknown, 3 terminated. 11 Not applicable, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 6, Terminated 3, Active not recruiting 1, Unknown 1 |
| Phase 2 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Liver Fibroses: new trials by email Literature Review of Liver Fibroses trials Research Report on Liver Fibroses
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Zinc Sulphate in Treatment Fibrosis in HBV Patient Receiving Antiviral Therapy Entecavir (ETV), Zinc (zinc sulphate) - Liver Fibroses, HBV (Hepatitis B Virus) | Phase 2 | Not yet recruiting | Tanta University | 44 | 2025-09-01 | 2025-08-28 |
| Safety and Efficacy of Atorvastatin v. Placebo on HCC Risk Atorvastatin 20mg, Placebo - Liver Fibroses, Cirrhosis | Phase 2 | Recruiting | Raymond Chung | 60 | 2023-05-10 | 2026-10-07 |
| A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG) Insulin Resistance, Quality of Life Assessment, Liver Function Test - Non-alcoholic Steatohepatitis (NASH), Endoscopic Sleeve Gastroplasty | Not applicable | Active not recruiting | Brigham and Women's Hospital | 20 | 2021-05-06 | 2025-12-02 |
| Clinical Performance of LIVERFASt Test Compared w/ Liver Biopsy in Patients w/ NAFLD. LIVERFASt - Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis | Not applicable | Completed | Fibronostics USA, Inc | 241 | 2021-01-07 | 2022-08-02 |
| Liquid Biopsy for NASH and Liver Fibrosis Liver Biopsy - NASH - Nonalcoholic Steatohepatitis, Liver Fibroses | Completed | Catholic University of the Sacred Heart | 150 | 2020-12-16 | 2021-05-19 | |
| Integrated Diagnostics for Early Diagnosis of Liver Disease Blood tests for Single Nucleotide Polymorphisms, Faecal microbiome analysis, Serum for diagnostic biomarkers - Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis | Recruiting | Manchester University NHS Foundation Trust | 1200 | 2020-10-21 | 2026-02-09 | |
| The Sonic Incytes Liver Incytes System, Evaluation of Liver Fibrosis and Steatosis Versus MRE and MRI PDFF Liver Incytes System - Non-Alcoholic Fatty Liver Disease (NAFLD), Non-Alcoholic Steatohepatitis (NASH) | Not applicable | Completed | Sonic Incytes | 164 | 2020-10-21 | 2026-07-20 |
| The EUS ShearWave Elastography Liver Fibrosis Study ShearWave Elastography (SWE) in Endoscopic Ultrasound (EUS), FibroScan, ALOKA ARIETTA 850 - - Liver Fibroses | Completed | Olympus Corporation of the Americas | 52 | 2020-07-14 | 2021-09-09 | |
| EUS Elastography for Predicting Cirrhotic-related Complications EUS elastography - Liver Fibroses | Active not recruiting | Chinese University of Hong Kong | 50 | 2019-11-04 | 2026-03-19 | |
| Comparative and Additive Diagnostic Performance of Magnetic Resonance Elastography (MRE) and Corrected-T1 (cT1) for Fibrosis and Inflammation in Nonalcoholic Steatohepatitis (NASH) Using Histology As Reference Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis | Completed | University of California, San Diego | 30 | 2019-05-21 | 2024-11-25 | |
| Evaluation of the Effect of IHHT on Vascular Stiffness and Elasticity of the Liver Tissue in Patients With MS. Interval hypoxic-hyperoxic training (IHHT) using respiratory therapy unit ReOxy., Simulating Interval hypoxic-hyperoxic training (IHHT) using respiratory therapy unit ReOxy. - Vascular Stiffness, Liver Fibroses | Not applicable | Completed | I.M. Sechenov First Moscow State Medical University | 62 | 2019-04-10 | 2021-03-10 |
| The Use of Novel Diagnostic Tools to Increase Detection of Early Fibrosis in Cystic Fibrosis Related Liver Disease to Improve Clinical Management Cystic Fibrosis, Liver Fibroses | Completed | Manchester University NHS Foundation Trust | 157 | 2019-02-15 | 2024-05-01 | |
| Accuracy of Imaging Techniques in Diagnosing Steatohepatitis and Fibrosis in NAFLD Patients Ultrasound and Magnetic Resonance - Non-Alcoholic Fatty Liver Disease, Steatohepatitis, Nonalcoholic | Not applicable | Completed | Azienda USL Reggio Emilia - IRCCS | 28 | 2019-01-01 | 2026-07-24 |
| Prevalence of Liver Fibrosis and Cirrhosis in Patients With Squamous Cell Carcinoma of the Head and Neck Evaluation of the hepatic fibrosis - Liver Fibroses, Liver Cirrhoses | Not applicable | Terminated | Centre Hospitalier Universitaire, Amiens | 2 | 2018-12-13 | 2026-06-25 |
| Effect of Some Drugs on Liver Fibrosis Candesartan, Ramipril - Liver Fibroses | Phase 3 | Recruiting | Sherief Abd-Elsalam | 45 | 2018-10-01 | 2018-12-10 |
| Liver Fibrosis in Peri-menopausal Women Nonalcoholic Steatohepatitis, Liver Fibroses | Unknown | Chang Gung Memorial Hospital | 200 | 2018-08-01 | 2018-08-21 | |
| Competitive Accuracy of Radiological Imaging Compared to Liver Biopsy in Patients With Liver Fibrosis Liver elastography (2D-SWE), Liver scintigraphy with 99mTc-mebrofenin - Liver Fibroses, Liver Cirrhosis | Completed | Vilnius University | 72 | 2018-08-01 | 2021-08-17 | |
| Liver Steatosis and Stiffness in HIV Fibroscan - HIV Infections, Fatty Liver | Unknown | Chang Gung Memorial Hospital | 200 | 2018-08-01 | 2018-08-21 | |
| Liver, Pancreas and Thyroid Function in Burn Patients Ultrasound/transient elastography - Burns, Liver Fibroses | Withdrawn | The University of Texas Medical Branch, Galveston | 2018-06-25 | 2023-06-18 | ||
| Increased Liver Stiffness: A Study of Acoustic Radiation Force Impulse (ARFI) Elastography Ultrasound with ARFI (acoustic radiation force impulse), Ultrasound with backscatter imaging - Liver Fibroses | Completed | University of Michigan | 25 | 2018-04-11 | 2020-06-02 |
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Liver Cirrhosis (33) · Non-alcoholic Fatty Liver Disease (12) · Fatty Liver (5) · Fibrosis (3) · Liver Diseases (3) · Diabetes Mellitus (2) · Hepatitis (2) · Metabolic Syndrome (2) · Obesity (2) · Acquired Immunodeficiency Syndrome (1) · Alcohol-Induced Disorders (1) · Bone Diseases, Metabolic (1) · Burns (1) · Carcinoma, Hepatocellular (1) · Cardiovascular Diseases (1)
Digestive System Diseases (33) · Pathologic Processes (33) · Pathological Conditions, Signs and Symptoms (33) · Fibrosis (30) · Liver Diseases (30) · Fatty Liver (9) · Nutritional and Metabolic Diseases (5) · Glucose Metabolism Disorders (4) · Alcohol-Related Disorders (3) · Chemically-Induced Disorders (3) · Endocrine System Diseases (3) · Hepatitis (3) · Immune System Diseases (3) · Metabolic Diseases (3) · Nutrition Disorders (3)
Ultrasonography (4) · Elasticity Imaging Techniques (2) · Atorvastatin (1) · Ethanol (1) · Hematologic Tests (1) · Liver Function Tests (1) · Magnetic Resonance Imaging (1) · Polymorphism, Single Nucleotide (1) · Ramipril (1) · Zinc (1) · Zinc Sulfate (1) · aramchol (1) · candesartan (1) · entecavir (1)
Chang Gung Memorial Hospital (2) · Chinese University of Hong Kong (2) · Manchester University NHS Foundation Trust (2) · Seoul National University Hospital (2) · Azienda USL Reggio Emilia - IRCCS (1) · Brigham and Women's Hospital (1) · Catholic University of the Sacred Heart (1) · Centre Hospitalier Universitaire, Amiens (1) · Children's Hospital Medical Center, Cincinnati (1) · Children's Mercy Hospital Kansas City (1) · Fibronostics USA, Inc (1) · Galmed Research and Development, Ltd. (1) · I.M. Sechenov First Moscow State Medical University (1) · Kaohsiung Medical University Chung-Ho Memorial Hospital (1) · Odense University Hospital (1)
United States (12) · Italy (4) · Hong Kong (3) · South Korea (3) · Taiwan (3) · France (2) · Lithuania (2) · United Kingdom (2) · Chile (1) · Denmark (1) · Egypt (1) · Georgia (1) · Germany (1) · Israel (1) · Mexico (1)
Abeer El-Motwally, Msc (1) · Aleksander Krag, MD, PhD (1) · Algirdas E Tamosiunas, MD, PhD (1) · Chia-Yen Dai (1) · Ching-I Huang (1) · Chung-Feng Huang (1) · Claude B Sirlin, MD (1) · Daniele Pastori, MD (1) · David Diehl, MD (1) · David N. Herndon, MD (1) · Francesco Angelico, MD (1) · Francesco Baratta, MD (1) · Frank DiPaola, MD (1) · Gamal Badra, Prof (1)
PMID 11095334, PMID 21751301, PMID 22229701, PMID 24280876, PMID 25851300, PMID 26004669, PMID 26226095, PMID 26269292, PMID 31887443, PMID 32925554, PMID 34401690, PMID 34513946, PMID 34621052, PMID 34925649, PMID 35327522, PMID 35820779, PMID 37592403, PMID 38053913, PMID 39437136, PMID 39601324, PMID 40205145, PMID 41273899, PMID 41299502, PMID 9193771
U54CA193417 (1)