9 completed, 1 recruiting, 1 terminated. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 6, Recruiting 1 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
Follow aramchol: new trials by email Literature Review of aramchol trials Research Report on aramchol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single and Multiple Dose Pharmacokinetics (PK) of Aramchol From an Aramchol Meglumine Tablet Aramchol - Healthy | Phase 1 | Recruiting | Galmed Pharmaceuticals Ltd | 32 | 2025-12-25 | 2026-09-10 |
| An Open-Label, Two-Part Study Designed to Assess the Absolute Bioavailability and Mass Balance of Aramchol Aramchol - NASH | Phase 1 | Completed | Galmed Pharmaceuticals Ltd | 6 | 2020-06-17 | 2023-05-24 |
| Comparison of Aramchol Concentrations With Once or Twice Daily Dosing Aramchol - Healthy | Phase 1 | Completed | Galmed Pharmaceuticals Ltd | 16 | 2018-12-08 | 2019-08-09 |
| Study of Potential for Drug Interactions Mediated by CYP3A4 Inhibition With Aramchol in Healthy Volunteers Aramchol, Midazolam, Atorvastatin - Healthy | Phase 1 | Completed | Galmed Pharmaceuticals Ltd | 15 | 2018-11-12 | 2019-08-22 |
| Pharmacokinetics of Single and Multiple Escalating Doses of Aramchol Administered Under Fed Conditions in Healthy Chinese Volunteers Aramchol, Placebo - Healthy Volunteers | Phase 1 | Completed | Galmed Pharmaceuticals Ltd | 64 | 2016-05-01 | 2016-12-21 |
| Aramchol for HIV-associated Nonalcoholic Fatty Liver Disease and Lipodystrophy Aramchol, Placebo - Nonalcoholic Fatty Liver Disease, HIV | Phase 2 | Completed | University of California, San Diego | 50 | 2016-01-01 | 2020-07-17 |
| A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH Aramchol - Fatty Liver, Non-Alcoholic Steatohepatitis | Phase 2 | Completed | Galmed Research and Development, Ltd. | 247 | 2015-04-29 | 2021-07-14 |
| Medical Dissolution of Cholesterol Gallstones Using Oral Aramchol - A Proof of Concept Phase IIa Study Aramchol, Placebo, Ultrasound - Gallstones | Phase 2 | Terminated | Galmed Pharmaceuticals Ltd | 10 | 2014-10-01 | 2015-10-05 |
| Pharmacokinetics of Single and Multiple Escalating Doses of Aramchol and Food Effect in Healthy Volunteers Aramchol, Placebo - Healthy Volunteers | Phase 1 | Completed | Galmed Pharmaceuticals Ltd | 66 | 2014-04-01 | 2015-02-27 |
| Study of Aramchol in Patients With Fatty Liver Disease or Nonalcoholic Steatohepatitis Aramchol, Placebo - Non-Alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis | Phase 2 | Completed | Galmed Medical Reserch | 60 | 2010-11-01 | 2012-01-31 |
| A Phase 1 Single and Multiple-Dose Study of Aramchol in Healthy Male Volunteers Aramchol - Healthy | Phase 1 | Completed | Galmed Medical Reserch | 41 | 2008-09-01 | 2010-11-03 |
Fatty Liver (3) · Non-alcoholic Fatty Liver Disease (3) · Obesity (2) · Diabetes Mellitus (1) · Fibrosis (1) · Gallstones (1) · Hypercholesterolemia (1) · Insulin Resistance (1) · Liver Cirrhosis (1) · Liver Diseases (1) · Metabolic Syndrome (1)
Galmed Pharmaceuticals Ltd (7) · Galmed Medical Reserch (2) · Galmed Research and Development, Ltd. (1) · University of California, San Diego (1)
Israel (4) · United Kingdom (4) · United States (3) · Chile (1) · France (1) · Georgia (1) · Germany (1) · Hong Kong (1) · Italy (1) · Lithuania (1) · Mexico (1) · Romania (1)
Adeep Puri, M.D. (2) · Asnat Raziel, MD (1) · Christina Yeung, MBBS (1) · Jacob Atsmon, M.D. (1) · John Posner, PhD, FRCP (1) · Maya Halpern, MD (1) · Ran Oren, Doctor (1) · Rohit Loomba, M.D. (1) · Vlad Ratziu, MD, PhD (1)