9 completed, 3 recruiting, 3 unknown, 1 active not recruiting. 7 Not applicable, 3 Phase 1, 3 Phase 2, 1 Early Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 4, Unknown 2, Active not recruiting 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 2 | 3 | Completed 3 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Kidney Dysfunction: new trials by email Literature Review of Kidney Dysfunction trials Research Report on Kidney Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response Vitamin B3 - Heat Strain, Healthy Volunteer Study | Early Phase 1 | Recruiting | Beth Israel Deaconess Medical Center | 28 | 2026-01-26 | 2026-02-05 |
| meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis Empagliflozin 25 MG - Peritoneal Dialysis Complication, End Stage Kidney Disease | Phase 3 | Recruiting | University Health Network, Toronto | 20 | 2024-09-01 | 2026-05-01 |
| Azilsartan in Patients With Diabetic Kidney Disease and Hypertension Azilsartan, Losartan - Proteinuria, Kidney Dysfunction | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 106 | 2023-04-01 | 2023-03-03 |
| Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD Empagliflozin, Placebo - End-stage Kidney Disease, Kidney Disease, Chronic | Phase 1 | Completed | University of Utah | 62 | 2023-03-21 | 2025-08-12 |
| Renal Considerations in the Heat Stress Recommendations (Aim2) Fluid replacement, No fluid replacement - Hot Weather; Adverse Effect, Kidney Dysfunction | Not applicable | Completed | Indiana University | 18 | 2022-08-01 | 2023-11-08 |
| Clinical Impact of the IBox As an Early Intervention TooL Predigraft - Kidney Diseases, Kidney Disease, Chronic | Not applicable | Active not recruiting | Predict4Health | 507 | 2022-02-18 | 2024-10-04 |
| Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE) Hypertension, Left Ventricular Hypertrophy | Recruiting | Wake Forest University Health Sciences | 125 | 2021-05-19 | 2025-12-11 | |
| Renal Considerations in the Heat Stress Recommendations 23.0°C WBGT - Fixed Work Rate, 25.5°C WBGT - Fixed Work Rate, 27.5°C WBGT - Fixed Work Rate - Hot Weather; Adverse Effect, Kidney Dysfunction | Not applicable | Completed | Indiana University | 38 | 2021-03-01 | 2023-11-08 |
| Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis Percutaneous Nephrostomy, Double J catheter - Urolithiasis, Urologic Diseases | Not applicable | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 204 | 2020-07-15 | 2024-02-28 |
| Music Therapy Intervention During Kidney Biopsy. music therapy intervention - Kidney Diseases, Kidney Dysfunction | Not applicable | Completed | Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari | 120 | 2020-06-01 | 2022-07-20 |
| Dynamic Measurement of Renal Functional Reserve as a Predictor of Long-Term Renal Function sinistrin clearance dynamic measurement - Adult Polycystic Kidney Disease, Kidney Neoplasms | Not applicable | Unknown | Thomas Mueller | 30 | 2018-06-01 | 2018-05-14 |
| A Study of Novel Biomarkers of Kidney Dysfunction at Liver Transplant Blood sample for serum and plasma biomarkers:, Urine sample for biomarkers, Cardiac bio-impedance (Cardioscreen Medis) - Liver Transplantation, Liver Transplant; Complications | Completed | University of Edinburgh | 55 | 2018-01-15 | 2024-05-07 | |
| Platelet Aggregation in Patients With Coronary Artery Disease and Kidney Dysfunction Taking Clopidogrel or Ticagrelor Clopidogrel, Ticagrelor - Platelet Aggregation, Adenosine | Phase 2 | Completed | University of Sao Paulo | 90 | 2017-11-07 | 2020-04-24 |
| Pharmacokinetics Study of Nemonoxacin Malate Capsules in Subjects With Severe Impaired Renal Function Nemonoxacin - Kidney Dysfunction | Phase 1 | Unknown | Zhejiang Medicine Co., Ltd. | 24 | 2017-04-05 | 2018-04-03 |
| Safety & Efficacy of Zirconium Silicate in Chronic Kidney Disease or Moderate Kidney Dysfunction With Mild Hyperkalemia Zirconium silicate (ZS), Placebo - Hyperkalemia, Chronic Kidney Disease | Phase 2 | Completed | ZS Pharma, Inc. | 90 | 2011-11-30 | 2018-06-29 |
| The Effects of Decreasing the Lasix Dose on the Cardiorenal System Furosemide - Heart Failure, Kidney Dysfunction | Phase 1 / Phase 2 | Completed | Mayo Clinic | 41 | 2009-07-01 | 2015-07-20 |
| Shift to Everolimus (RAD) Kidney Sparing Study cyclosporine, Mycophenolate mofetil, Everolimus - Kidney Dysfunction, Heart Transplantation | Phase 4 | Terminated | University of Bologna | 34 | 2006-09-01 | 2010-01-12 |
Kidney Diseases (4) · Renal Insufficiency, Chronic (4) · Kidney Failure, Chronic (3) · Renal Insufficiency (3) · Dehydration (2) · Hypertension (2) · Hyperthermia (2) · Proteinuria (2) · Acute Kidney Injury (1) · Albuminuria (1) · Anxiety Disorders (1) · Bites and Stings (1) · Calculi (1) · Coronary Artery Disease (1) · Diabetic Nephropathies (1)
Pathological Conditions, Signs and Symptoms (10) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Male Urogenital Diseases (9) · Pathologic Processes (9) · Urogenital Diseases (9) · Urologic Diseases (8) · Chronic Disease (5) · Disease Attributes (5) · Kidney Diseases (5) · Signs and Symptoms (5) · Cardiovascular Diseases (4) · Nutritional and Metabolic Diseases (4) · Heart Diseases (3) · Metabolic Diseases (3)
empagliflozin (2) · Blood Specimen Collection (1) · Clopidogrel (1) · Cyclosporine (1) · Everolimus (1) · Furosemide (1) · Losartan (1) · Mycophenolic Acid (1) · Nephrostomy, Percutaneous (1) · Nephrotomy (1) · Niacinamide (1) · Stents (1) · Ticagrelor (1) · Tomography, Optical Coherence (1) · azilsartan (1)
Indiana University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari (1) · Beth Israel Deaconess Medical Center (1) · Mayo Clinic (1) · Predict4Health (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Thomas Mueller (1) · University Health Network, Toronto (1) · University of Bologna (1) · University of Edinburgh (1) · University of Sao Paulo (1) · University of Utah (1) · Wake Forest University Health Sciences (1) · ZS Pharma, Inc. (1)
United States (7) · China (2) · Italy (2) · United Kingdom (2) · Austria (1) · Brazil (1) · Canada (1) · France (1) · Germany (1) · Israel (1) · Netherlands (1) · Spain (1) · Switzerland (1)
Ad Hendrikx, dr. (1) · Andrew M South, MD, MS (1) · Angelo Branzi, MD (1) · Henrik Rasmussen, MD (1) · Horng H Chen, MD (1) · Jonathan A Fallowfield, PhD (1) · Nathan H Raines, MD MPH (1) · Sunita KS Singh, MD MSc FRCPC (1) · Thomas F Mueller, Prof. (1) · Zhida Chen (1)
PMID 25262369, PMID 32588430, PMID 35224730, PMID 36211944, PMID 37907448, PMID 38682786, PMID 40914830, PMID 41830115
2017 (1), K23DK138320 (1), K23HL148394 (1), P01HL076611 (1), R01DK131265 (1), R01HL084155 (1), UL1TR000135 (1)