14 completed, 5 unknown, 4 recruiting, 2 enrolling by invitation. 4 Not applicable, 4 Phase 4, 2 Phase 3, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Recruiting 3, Unknown 1 |
| Phase 4 | 4 | Completed 3, Enrolling by invitation 1 |
| Phase 3 | 2 | Enrolling by invitation 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Joint Infection: new trials by email Literature Review of Joint Infection trials Research Report on Joint Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Initial Oral Antibiotics for Bone and Joint Infections in Children Oral antibiotic treatment - Osteomyelitis Acute, Septic Arthritis | Recruiting | Copenhagen University Hospital, Rigshospitalet | 100 | 2024-11-15 | 2025-04-09 | |
| Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection All-cement articulating spacer, Durable, real-component articulating spacer, Rigid Spacer - Prosthetic-joint Infection, Knee Infection | Not applicable | Recruiting | Northwestern University | 153 | 2024-08-08 | 2026-08-24 |
| Performances of DendrisCHIP®OA in Bone and Joint Infections Bone Infection, Joint Infection | Withdrawn | Assistance Publique - Hôpitaux de Paris | 2023-12-01 | 2025-06-15 | ||
| Rate of Total Joint Infection 90-day After Surgery Following Irrigation With Next Science No-Rinse Solution vs SOC Alone No-Rinse Solution (NS), Saline irrigation - Joint Infection | Not applicable | Recruiting | Northwell Health | 936 | 2023-09-26 | 2025-05-23 |
| Side Effects of Antibiotics in Bone and Joint Infections Bone Infection, Joint Infection | Completed | University Hospital, Tours | 73 | 2023-08-11 | 2026-05-06 | |
| Interest in Probabilistic Antibiotic Therapy With Broad-spectrum Beta-lactams in Orthopedic Surgery Joint Infection | Unknown | University Hospital, Strasbourg, France | 150 | 2023-07-17 | 2024-01-05 | |
| Controlled Trial of Omadacycline Randomized Treatment Given for Bone and Joint Infection Omadacycline Pill, Standard of Care - Bone Infection, Joint Infection | Phase 2 | Active not recruiting | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 180 | 2023-05-09 | 2026-01-14 |
| Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA) PLG0206 - Joint Infection | Phase 1 | Completed | Peptilogics | 14 | 2022-03-31 | 2025-05-21 |
| Prevalence of Pathogens in Synovial Fluid Obtained From Emergency Department Patients Septic Arthritis, Joint Infection | Completed | Olive View-UCLA Education & Research Institute | 750 | 2021-09-01 | 2026-06-25 | |
| Or v IV Antibiotics for Infection Bactrim, Cefadroxil, Doxycycline Hcl - Joint Infection | Phase 3 | Enrolling by invitation | Rothman Institute Orthopaedics | 308 | 2021-01-25 | 2026-10-08 |
| Oral-only Antibiotics for Bone and Joint Infections in Children Oral co-amoxiclav or oral dicloxacillin only, IV ceftriaxon followed by oral co-amoxiclav or oral dicloxacillin - Osteomyelitis, Septic Arthritis | Phase 4 | Completed | Copenhagen University Hospital, Rigshospitalet | 180 | 2020-09-15 | 2025-04-13 |
| Effect of Sonication on Periprosthetic Joint Infection Treatment Strategy. Sonication method - Prosthesis-Related Infections, Hip Prosthesis Infection | Unknown | Bezmialem Vakif University | 56 | 2020-03-15 | 2021-01-07 | |
| Can Intraosseous Antibiotics Improve the Results of Irrigation & Debridement and Prosthetic Retention for PJI? Intraoperative Intraosseous Vancomycin - Joint Infection | Phase 4 | Enrolling by invitation | OrthoCarolina Research Institute, Inc. | 100 | 2020-01-14 | 2026-04-06 |
| Gut Microbiome of Patients Undergoing Antibiotic Therapy for Orthopedic Device-related Infection no intervention, observational only - Fractures, Bone, Infection, Bacterial | Completed | AO Research Institute Davos | 12 | 2019-11-01 | 2023-02-03 | |
| Biofilm Composition as a Predictive Biomarker for Prosthetic Joint Infection Revision surgery - Joint Infection | Completed | Portsmouth Hospitals NHS Trust | 35 | 2019-07-01 | 2023-04-07 | |
| Results of Extended Versus Single Dose Antibiotic Prophylaxis In Orthopedic Revision Arthroplasty in Nijmegen. Cefazolin - Infection Prosthesis Hip and Knee, Infection, Prosthesis Related | Phase 3 | Unknown | Radboud University Medical Center | 751 | 2019-01-01 | 2024-05-07 |
| Joint Infection Following ACL Reconstruction no intervention - Joint Infection | Completed | Peking University Third Hospital | 104 | 2019-01-01 | 2021-07-12 | |
| Biological Collection From Samples From The Gut Microbiota In Patients Having A Bone Or Joint Infection Treated By A Suppressive Subcutaneous Antibiotherapy With Betalactamine (CARBAMICROBIOTA) Biological Collection From Samples From The Gut Microbiota - Bone Infection, Joint Infection | Completed | Hospices Civils de Lyon | 14 | 2018-10-11 | 2025-12-09 | |
| Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections Dalbavancin, Vancomycin - Bone Infection, Osteomyelitis | Phase 4 | Completed | Infectious Diseases Physicians, Inc. | 41 | 2018-01-25 | 2023-10-03 |
| Microbiological Structure of Pathogens of Periprosthetic Infection of Large Joints in the Post-Covid Period Microbiological examination of the patient's biological material and determination of antibiotic resistance - Joint Infection, Periprosthetic Left Knee Joint Infection | Completed | Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty | 342 | 2018-01-01 | 2024-02-20 |
Showing 20 of 30. Sign in to see all of them.
Arthritis, Infectious (7) · Osteomyelitis (3) · Prosthesis-Related Infections (2) · Surgical Wound Infection (2) · Bacterial Infections (1) · COVID-19 (1) · Fractures, Bone (1) · Infections (1)
Infections (11) · Arthritis (7) · Joint Diseases (7) · Musculoskeletal Diseases (7) · Bone Diseases (3) · Bone Diseases, Infectious (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Postoperative Complications (3) · Wound Infection (2) · Bacterial Infections and Mycoses (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Lung Diseases (1) · Nidovirales Infections (1)
Anti-Bacterial Agents (2) · Cefazolin (2) · Vancomycin (2) · Amoxicillin-Potassium Clavulanate Combination (1) · Blood Cell Count (1) · Blood Culture (1) · Cefadroxil (1) · Clindamycin (1) · Daptomycin (1) · Dicloxacillin (1) · Nafcillin (1) · Reoperation (1) · Standard of Care (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1) · dalbavancin (1)
Hospices Civils de Lyon (5) · Bezmialem Vakif University (2) · Copenhagen University Hospital, Rigshospitalet (2) · AO Research Institute Davos (1) · Assistance Publique - Hôpitaux de Paris (1) · Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty (1) · First Affiliated Hospital of Fujian Medical University (1) · Hospital for Special Surgery, New York (1) · Infectious Diseases Physicians, Inc. (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Northwell Health (1) · Northwestern University (1) · Olive View-UCLA Education & Research Institute (1) · OrthoCarolina Research Institute, Inc. (1) · Ottawa Hospital Research Institute (1)
United States (10) · France (6) · China (2) · Denmark (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Canada (1) · Netherlands (1) · Russia (1) · Switzerland (1)
Adam I Edelstein, MD (1) · Allan Bybeck Nielsen, MD (1) · Amy Y. Kang, PharmD, BCIDP (1) · Anne-Laure Roux, PharmD, PhD (1) · Bart-Jan Kullberg, prof. Dr (1) · Donald Poretz, MD (1) · Emily R Dodwell, MD, MPH (1) · Giles Scuderi (1) · Julie Zielinski, M.D. (1) · Liu Zhang (1) · Loren G. Miller, MD, MPH (1) · Matthew Scarborough, MB BS (1) · Orkhan Aliyev, MD (1) · Philip Bejon, PhD (1)
PMID 31220276, PMID 35067748, PMID 36728573, PMID 37263683, PMID 39025092, PMID 39085523, PMID 42671259