4 completed, 4 withdrawn, 3 unknown, 1 active not recruiting. 15 Phase 1, 5 Phase 2.
Follow Intraabdominal Infections: new trials by email Literature Review of Intraabdominal Infections trials Research Report on Intraabdominal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers JKN2501, Placebo - Bacterial Infections, Urinary Tract Infections | Phase 1 | Recruiting | Joincare Pharmaceutical Group Industry Co., Ltd | 66 | 2025-08-22 | 2025-10-03 |
| Efficacy of Fuzheng Tongfu Jiedu Prescription for Treating Gastrointestinal Dysfunction Associated With Sepsis Fuzheng Tongfu Jiedu prescription (FZTFJD), Placebo - Sepsis Abdominal, Gastrointestinal Dysfunction | Phase 1 / Phase 2 | Not yet recruiting | Dongzhimen Hospital, Beijing | 70 | 2025-04-25 | 2025-04-18 |
| Precision Antibiotic Dosing for Appendectomy Cefoxitin - Appendicitis (Diagnosis) | Phase 1 | Active not recruiting | University of Michigan | 46 | 2025-02-28 | 2026-08-14 |
| Non-operative vs. Operative Management of Acute Appendicitis in Vulnerable Patient Populations Laparoscopic appendectomy, Antibiotics (IV transitioned to oral) - Acute Appendicitis | Phase 1 | Withdrawn | University of Texas Southwestern Medical Center | 2023-10-01 | 2024-03-26 | |
| Safety, Tolerability, and Pharmacokinetics of Sulopenem in Adolescents Sulopenem - Urinary Tract Infections, Pyelonephritis Acute | Phase 1 | Withdrawn | Iterum Therapeutics, International Limited | 2021-04-30 | 2022-06-13 | |
| Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis Sulfur hexafluoride lipid-type A microspheres - Appendicitis Acute | Phase 1 | Withdrawn | Boston Children's Hospital | 2020-07-15 | 2020-07-17 | |
| ZAVI APD ELF Protocol v2.2 Intravenous Infusion - Peritonitis, Pneumonia | Phase 1 | Unknown | Markus Zeitlinger | 20 | 2018-10-01 | 2021-09-08 |
| Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy Non-narcotic pain control - Appendicitis, Pain, Postoperative | Phase 1 / Phase 2 | Withdrawn | University of Utah | 2017-09-05 | 2020-02-07 | |
| Nebulized Analgesia for Laparoscopic Appendectomy Trial Ropivacaine, Normal saline - Appendicitis | Phase 1 / Phase 2 | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 200 | 2016-01-01 | 2016-03-22 |
| The Safety and Tolerability of Intra-abdominal t-PA and DNase on Peritonitis in Peritoneal Dialysis Patients Tissue Plasminogen Activator (tPA), recombinant deoxyribonuclease (DNase) - Peritoneal Dialysis, Peritoneal Dialysis, Continuous Ambulatory | Phase 1 | Terminated | Sir Charles Gairdner Hospital | 5 | 2016-01-01 | 2022-05-19 |
| A Study to Assess the Levels of Two Antibiotics in the Blood When Given Together and Separately CAZ104, Avibactam, Ceftazidime - Healthy | Phase 1 | Completed | Pfizer | 43 | 2011-09-01 | 2017-09-01 |
| Trial on Postoperative Outcomes According to the Number of Trocar During Laparoscopic Appendectomy appendectomy - Appendicitis, Pain | Phase 1 | Unknown | The Catholic University of Korea | 140 | 2009-01-01 | 2009-01-06 |
| Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections meropenem - Necrotizing Enterocolitis, Intra-abdominal Infection | Phase 1 / Phase 2 | Completed | The Emmes Company, LLC | 200 | 2008-06-01 | 2023-04-25 |
| Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels rhu-pGelsolin, Placebo - Low Gelsolin, Trauma | Phase 1 / Phase 2 | Completed | Critical Biologics Corporation | 40 | 2008-03-01 | 2010-09-29 |
| Autologous Fibrin Glues for Fistulas Closure Autologous platelet-rich fibrin glue (PRFG), Octreotide - Enterocutaneous Fistulas, Intra-abdominal Infection | Phase 1 | Completed | Jinling Hospital, China | 122 | 2008-01-01 | 2013-02-26 |
Appendicitis (6) · Peritonitis (3) · Urinary Tract Infections (3) · Pneumonia (2) · Sepsis (2) · Agnosia (1) · Bacterial Infections (1) · Burns (1) · Disease (1) · Enterocolitis, Necrotizing (1) · Fistula (1) · Infections (1) · Intestinal Fistula (1) · Meretoja syndrome (1)
Infections (14) · Digestive System Diseases (11) · Gastrointestinal Diseases (8) · Intestinal Diseases (8) · Gastroenteritis (7) · Cecal Diseases (6) · Pathological Conditions, Signs and Symptoms (6) · Pathologic Processes (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Male Urogenital Diseases (3) · Peritoneal Diseases (3) · Respiratory Tract Diseases (3) · Urogenital Diseases (3)
Anti-Bacterial Agents (1) · Appendectomy (1) · Cefoxitin (1) · Ceftazidime (1) · Infusions, Intravenous (1) · Meropenem (1) · Octreotide (1) · Ropivacaine (1) · Saline Solution (1) · Tissue Plasminogen Activator (1) · avibactam (1) · dornase alfa (1) · lactitol (1) · sulopenem (1)
Boston Children's Hospital (1) · Critical Biologics Corporation (1) · Dongzhimen Hospital, Beijing (1) · Iterum Therapeutics, International Limited (1) · Jinling Hospital, China (1) · Joincare Pharmaceutical Group Industry Co., Ltd (1) · Markus Zeitlinger (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Pfizer (1) · Sir Charles Gairdner Hospital (1) · The Catholic University of Korea (1) · The Emmes Company, LLC (1) · University of Michigan (1) · University of Texas Southwestern Medical Center (1) · University of Utah (1)
United States (5) · China (3) · Australia (1) · Austria (1) · Canada (1) · Hong Kong (1) · South Korea (1) · United Kingdom (1)
Aron Chakera, DPhil (1) · Danny Benjamin, MD, PhD, MPH (1) · Harriet Paltiel, MDCM (1) · Jin Liu, Dr (1) · Leonard Siew, MBCHB (1) · Manjunath Pai, PharmD (1) · Mirjana Kujacic, MD (1) · Paul Newell, MD (1) · Richard C Straube, MD (1) · Robert Baird, MDCM MSc (1) · Selene Tam, PhD (1) · Sneha Bhat (1) · Stephen J Fenton, MD (1) · Steven I Aronin, MD (1) · Wai M Chan, MBBS (1)
PMID 20393336, PMID 22955430, PMID 23473061, PMID 24183344, PMID 30221827, PMID 30366723