16 completed. 16 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 16 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 1 | Completed 1 |
Follow Intestinal Obstruction: new trials by email Literature Review of Intestinal Obstruction trials Research Report on Intestinal Obstruction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Follow-up and Steroid Treatment Results in Intussusception Methylprednisolone - Intussusception | Phase 1 / Phase 2 | Completed | Baskent University | 92 | 2019-12-24 | 2025-02-05 |
| A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection LB1148, Placebo - Ileus, Post-Operative Adhesions | Phase 2 | Completed | Palisade Bio | 112 | 2019-10-01 | 2024-06-21 |
| Study to Evaluate LB1148 for Return of Gastrointestinal Function, Decrease Post-Operative Ileus LB1148, Placebo - Ileus | Phase 2 | Completed | Newsoara Biopharma Co., Ltd. | 131 | 2019-07-09 | 2021-09-27 |
| Subcutaneous Methylnaltrexone Versus Placebo for Postoperative Ileus Prevention Methylnaltrexone, Placebo - Postoperative Ileus | Phase 2 | Completed | Ohio State University | 82 | 2019-02-21 | 2021-10-27 |
| The Effect of Foeniculum Vulgare Ironing on Gastrointestinal Recovery After Colorectal Resection Foeniculum Vulgare Seed Ironing - Colorectal Surgery, Foeniculum | Phase 2 | Completed | West China Hospital | 300 | 2018-10-20 | 2019-09-17 |
| Does Cediranib Prevent Bowel Perforation in Platinum-resistant Ovarian Cancer Cediranib - Bowel Obstruction, Ovarian Cancer | Phase 2 | Completed | Prof Gordon Jayson | 30 | 2018-05-14 | 2026-06-15 |
| Study to Assess Efficacy and Safety of Lanreotide Autogel 120 MG in Treatment of Clinical Symptoms Associated With Inoperable Malignant Intestinal Obstruction Lanreotide Autogel - Intestinal Obstruction | Phase 2 | Completed | Ipsen | 52 | 2014-11-19 | 2019-04-16 |
| The Effects of Gum Chewing on Bowel Function Recovery Following Cesarean Section Gum chewing - Paralytic Ileus | Phase 2 / Phase 3 | Completed | Chiang Mai University | 100 | 2010-05-01 | 2011-06-28 |
| Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea Eluxadoline, Placebo - Irritable Bowel Syndrome | Phase 2 | Completed | Furiex Pharmaceuticals, Inc | 807 | 2010-04-28 | 2019-10-22 |
| Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus Ipamorelin, placebo - Ileus | Phase 2 | Completed | Helsinn Therapeutics (U.S.), Inc | 117 | 2008-04-01 | 2017-04-14 |
| A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumonia Imipenem/cilastatin, Doripenem - Pneumonia, Ventilator-Associated, Pneumonia, Bacterial | Phase 2 | Completed | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 146 | 2007-10-01 | 2019-03-19 |
| Octreotide Compared to Placebo in Patients With Inoperable Bowel Obstruction Due to Peritoneal Carcinomatosis Octreotide LAR, Octreotide (Immediate release), methylprednisolone - Peritoneal Neoplasms, Intestinal Obstruction | Phase 2 | Completed | Novartis Pharmaceuticals | 64 | 2005-09-01 | 2011-09-23 |
| Movicol in Childhood Constipation (ProMotion Study) Polyethylene glycol 3350 NA bicarbonate NaCl KCl (Movicol), Lactulose - Feces, Impacted | Phase 2 | Completed | Norgine | 60 | 2000-10-01 | 2007-01-04 |
| Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction bowel obstruction management, quality-of-life assessment - Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction | Phase 1 / Phase 2 | Completed | Northwestern University | 2000-01-01 | 2012-06-06 | |
| Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction bowel obstruction management, quality-of-life assessment - Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction | Phase 1 / Phase 2 | Completed | Northwestern University | 2000-01-01 | 2012-06-06 | |
| Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery octreotide acetate - Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction | Phase 2 | Completed | Northwestern University | 1999-10-01 | 2012-06-06 |
Ileus (6) · Colonic Neoplasms (3) · Colorectal Neoplasms (3) · Constipation (3) · Gastrointestinal Stromal Tumors (3) · Stomach Neoplasms (3) · Bile Duct Neoplasms (2) · Ovarian Neoplasms (2) · Pancreatic Neoplasms (2) · Rectal Neoplasms (2) · Abdominal Abscess (1) · Bacterial Infections (1) · Carcinoma (1) · Carcinoma, Ovarian Epithelial (1)
Digestive System Diseases (15) · Gastrointestinal Diseases (15) · Intestinal Diseases (15) · Neoplasms (5) · Neoplasms by Site (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Digestive System Neoplasms (4) · Neoplasms by Histologic Type (4) · Colonic Diseases (3) · Endocrine Gland Neoplasms (3) · Endocrine System Diseases (3) · Gastrointestinal Neoplasms (3) · Intestinal Neoplasms (3)
Methylprednisolone (2) · Octreotide (2) · Chewing Gum (1) · Cilastatin, Imipenem Drug Combination (1) · Doripenem (1) · Exercise (1) · Lactulose (1) · Steroids (1) · cediranib (1) · eluxadoline (1) · ipamorelin (1) · methylnaltrexone (1)
Northwestern University (3) · Baskent University (1) · Chiang Mai University (1) · Furiex Pharmaceuticals, Inc (1) · Helsinn Therapeutics (U.S.), Inc (1) · Ipsen (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · Newsoara Biopharma Co., Ltd. (1) · Norgine (1) · Novartis Pharmaceuticals (1) · Ohio State University (1) · Palisade Bio (1) · Prof Gordon Jayson (1) · West China Hospital (1)
United States (7) · China (2) · United Kingdom (2) · Belgium (1) · France (1) · Thailand (1) · Turkey (Türkiye) (1)
Willis G. Parsons, MD, PC (2) · Andrew Clamp (1) · David CA Candy, MD (1) · J. Cameron Muir, MD (1) · Kittipat Charoenkwan, MD (1) · Mitch Jones, MD (1) · Suzan Allen (1) · Ziqiang Wang, MD (1)
PMID 15351109, PMID 16819379, PMID 16850151, PMID 19610681, PMID 20334152, PMID 23583433, PMID 24813429, PMID 25331030, PMID 25819420, PMID 26867333, PMID 28167156, PMID 29067571, PMID 29621360, PMID 34798295, PMID 34844770, PMID 39914152
2016 (1)