9 completed. 9 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 9 | Completed 9 |
Follow Hypoglycemia: new trials by email Literature Review of Hypoglycemia trials Research Report on Hypoglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anaplerotic Therapy Using Triheptanoin for Patients With Glycogen Storage Disease Type I Triheptanoin - Glycogen Storage Disease Type I | Early Phase 1 | Completed | Areeg El-Gharbawy | 4 | 2020-10-16 | 2021-12-15 |
| Adrenergic System in Islet Transplantation Phentolamine, Propranolol, Placebo - Type1diabetes, Hypoglycemia | Early Phase 1 | Completed | University of Pennsylvania | 9 | 2017-01-20 | 2026-04-27 |
| Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes Insulin, Glucose, Potassium phosphate - Hypoglycemia | Early Phase 1 | Completed | University of Minnesota | 27 | 2016-11-01 | 2021-02-01 |
| Differing Levels of Hypoglycemia Glucose clamp - Hypoglycemia | Early Phase 1 | Completed | University of Maryland, Baltimore | 32 | 2015-07-01 | 2026-11-06 |
| Preventing Hypoglycemia During Exercise With Proactive Snacking on Closed Loop Medtronic MiniMed Closed Loop (CL) System, Snacking - Type 1 Diabetes | Early Phase 1 | Completed | Yale University | 15 | 2015-01-01 | 2020-04-20 |
| GLP-1 and Hypoglycemia Glucagon-Like Peptide- 1 (GLP-1) infusion, Placebo Comparator: Saline Infusion - Type 2 Diabetes Mellitus | Early Phase 1 | Completed | University of Maryland, Baltimore | 28 | 2013-07-01 | 2026-11-06 |
| Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus Dehydroepiandrosterone, Placebo - Type 1 Diabetes | Early Phase 1 | Completed | University of Maryland, Baltimore | 50 | 2010-10-01 | 2019-09-12 |
| Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia Insulin - Brain Neoplasms, Intracranial Aneurysm | Early Phase 1 | Completed | Northwestern University | 120 | 2009-10-01 | 2019-12-13 |
| Metabolic Causes of Thrombosis in Type 2 Diabetes - Question 4 Hyperinsulinemic Hypoglycemic Clamp - Type 2 Diabetes | Early Phase 1 | Completed | University of Maryland, Baltimore | 20 | 2007-05-01 | 2019-09-12 |
Diabetes Mellitus, Type 1 (2) · Diabetes Mellitus, Type 2 (2) · Brain Neoplasms (1) · Glycogen Storage Disease Type I (1) · Insulin Resistance (1) · Intracranial Aneurysm (1) · Motor Activity (1)
Glucose Metabolism Disorders (9) · Metabolic Diseases (9) · Nutritional and Metabolic Diseases (9) · Diabetes Mellitus (4) · Endocrine System Diseases (4) · Autoimmune Diseases (2) · Immune System Diseases (2) · Aneurysm (1) · Behavior (1) · Brain Diseases (1) · Carbohydrate Metabolism, Inborn Errors (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Central Nervous System Neoplasms (1) · Cerebrovascular Disorders (1)
Glucose (2) · Insulin (2) · Insulin, Regular, Human (2) · Dehydroepiandrosterone (1) · Drug Delivery Systems (1) · Glucagon-Like Peptide 1 (1) · Glucose Clamp Technique (1) · Phentolamine (1) · Propranolol (1) · Snacks (1) · Sodium Chloride (1) · potassium phosphate (1) · triheptanoin (1)
University of Maryland, Baltimore (4) · Areeg El-Gharbawy (1) · Northwestern University (1) · University of Minnesota (1) · University of Pennsylvania (1) · Yale University (1)
United States (9)
Stephen N. Davis, MD (2) · Areeg El-Gharbawy, MD (1) · Dhanesh Gupta, MD (1) · Jennifer Sherr, MD, PhD (1) · Michael R Rickels, MD., MS (1) · Silvia Mangia, PhD (1) · Stephen N Davis, MBBS (1)
PMID 20587723, PMID 25695946, PMID 41712301
R01DK069803 (1), R01DK091331 (1), T32DK063703 (1)