20 completed. 20 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 20 | Completed 20 |
Follow Hypertriglyceridemia: new trials by email Literature Review of Hypertriglyceridemia trials Research Report on Hypertriglyceridemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Use of Icosapent Ethyl on Vascular Progenitor Cells in Individuals With Elevated Cardiovascular Risk Icosapent Ethyl 1000 MG Oral Capsule [Vascepa] - Cardiovascular Diseases, Cardiovascular Risk Factor | Phase 4 | Completed | Canadian Medical and Surgical Knowledge Translation Research Group | 70 | 2020-09-24 | 2024-04-02 |
| The Effect of Omega-3 FA on Hypertriglyceridemia in Patients With T2DM(OCEAN) Omega-3 fatty acid, Placebos - Type 2 Diabetes Mellitus, Hypertriglyceridemia | Phase 4 | Completed | Shanghai Jiao Tong University School of Medicine | 309 | 2017-05-01 | 2023-10-30 |
| Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin Therapy Vascepa, placebo - Hypertriglyceridemia | Phase 4 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 80 | 2017-03-28 | 2023-02-21 |
| Vascular and Metabolic Effects of Fenofibrate/Omega vs Fenofibrate placebo, fenofibrate/omega, fenofibrate - Hypertriglyceridemia | Phase 4 | Completed | Gachon University Gil Medical Center | 120 | 2012-01-01 | 2014-11-04 |
| Carbohydrate Metabolism Disorder Frequency in Hypertriglyceridemia Induced by Bexarotene of Cutaneous T Cell Lymphoma oral glucose tolerance test (OGTT) - Hypertriglyceridemia, Cutaneous T Cell Lymphoma | Phase 4 | Completed | Rennes University Hospital | 10 | 2012-01-01 | 2017-07-21 |
| A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic fenofibrate - Dyslipidemias, Cardiovascular Diseases | Phase 4 | Completed | Abbott | 506 | 2011-10-01 | 2015-03-17 |
| Vascular and Metabolic Effects of Omega-3 Fatty Acids placebo, omega - Hypertriglyceridemia | Phase 4 | Completed | Gachon University Gil Medical Center | 176 | 2011-03-01 | 2014-11-04 |
| Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrome Saffron tablet, Barberry tablet, Placebo - Metabolic Syndrome, Hypercholesterolemia | Phase 4 | Completed | Birjand University of Medical Sciences | 732 | 2010-01-01 | 2012-06-21 |
| Differential Metabolic Effects of Fenofibrate and Fatty Acid fenofibrate, fatty acid, placebo - Hypertriglyceridemia | Phase 4 | Completed | Gachon University Gil Medical Center | 150 | 2009-11-01 | 2011-05-10 |
| Lovaza® and Microvascular Function in Type 2 Diabetes omega-3-ethyl esters, Placebo - Hypertriglyceridemia, Diabetic Neuropathy | Phase 4 | Completed | Eastern Virginia Medical School | 44 | 2009-10-01 | 2017-05-09 |
| Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects Lovaza, fosamprenavir/ritonavir - Hypertriglyceridemia, HIV Infection | Phase 4 | Completed | Felizarta, Franco, M.D. | 36 | 2009-09-01 | 2012-04-18 |
| Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia Lovaza - High Triglycerides, Hypercholesterolemia | Phase 4 | Completed | Massachusetts General Hospital | 65 | 2009-07-01 | 2017-07-02 |
| Niacin, N-3 Fatty Acids and Insulin Resistance omega-3 acid ethyl esters, extended release niacin, placebo - Metabolic Syndrome, Hypertriglyceridemia | Phase 4 | Completed | University of South Dakota | 68 | 2007-10-01 | 2021-10-26 |
| Effect of Plant Sterols Esterified to Fish Oil Fatty Acids on Plasma Lipid Levels Plant sterols esters, placebo - Dyslipidemia | Phase 4 | Completed | Enzymotec | 91 | 2007-03-01 | 2012-01-13 |
| Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients rosuvastatin - Hypertriglyceridemia, Hyperlipoproteinemia Type IV | Phase 4 | Completed | AstraZeneca | 334 | 2007-01-01 | 2010-12-16 |
| Omega-3 Fatty Acids for High Triglycerides in HIV-infected Patients Omega-3 fatty acid administration, Placebo - HIV Infections, AIDS | Phase 4 | Completed | Brown, Todd, M.D., Ph.D. | 48 | 2006-10-01 | 2014-11-05 |
| A Second Open-Label Extension of a Double-Blind, Parallel, Phase IV Study to Assess the Efficacy and Safety of Adjunctive Lovaza® (Formerly Known as Omacor®) Therapy in Hypertriglyceridemic Subjects Treated With Antara™ Antara (fenofibrate) + Lovaza (omega-3-acid ethyl esters) - Hypertriglyceridemia | Phase 4 | Completed | GlaxoSmithKline | 93 | 2006-03-01 | 2011-01-25 |
| Evaluation of Efficacy and Safety of Omacor (Omega-3-acid Ethyl Esters) as Add-on Therapy in Hypertriglyceridemic Subjects Treated With Antara (Fenofibrate) Followed by an 8-week Extension Antara (fenofibrate) + Lovaza, Antara (fenofibrate) - Hypertriglyceridemia | Phase 4 | Completed | GlaxoSmithKline | 167 | 2005-10-01 | 2009-12-14 |
| Effects of Fenofibrate on Adipocytokine Levels In Hypertriglyceridemic Patients fenofibrate - Hypertriglyceridemia | Phase 4 | Completed | Gachon University Gil Medical Center | 2005-01-01 | 2008-09-03 | |
| Pharmacological Regulation of Fat Transport in Metabolic Syndrome Atorvastatin and fenofibrate - Obesity, Lipid Disorders | Phase 4 | Completed | The University of Western Australia | 11 | 2001-06-01 | 2008-03-11 |
Insulin Resistance (6) · Cardiovascular Diseases (3) · Dyslipidemias (3) · Hypercholesterolemia (3) · Diabetes Mellitus, Type 2 (2) · HIV Infections (2) · Metabolic Syndrome (2) · Acquired Immunodeficiency Syndrome (1) · Bipolar Disorder (1) · Diabetic Neuropathies (1) · Hyperglycemia (1) · Hyperlipidemias (1) · Hyperlipoproteinemia Type II (1) · Hyperlipoproteinemia Type IV (1)
Metabolic Diseases (20) · Nutritional and Metabolic Diseases (20) · Hyperlipidemias (19) · Lipid Metabolism Disorders (19) · Dyslipidemias (17) · Glucose Metabolism Disorders (9) · Hyperinsulinism (7) · Diabetes Mellitus (3) · Endocrine System Diseases (3) · Immune System Diseases (3) · Blood-Borne Infections (2) · Communicable Diseases (2) · Genital Diseases (2) · Immunologic Deficiency Syndromes (2) · Infections (2)
Fenofibrate (7) · Omacor (6) · Fatty Acids, Omega-3 (2) · eicosapentaenoic acid ethyl ester (2) · Atorvastatin (1) · Combined Modality Therapy (1) · Fatty Acids (1) · Glucose Tolerance Test (1) · Niacin (1) · Ritonavir (1) · Rosuvastatin Calcium (1) · crocin (1) · fosamprenavir (1)
Gachon University Gil Medical Center (4) · GlaxoSmithKline (2) · Abbott (1) · AstraZeneca (1) · Birjand University of Medical Sciences (1) · Brown, Todd, M.D., Ph.D. (1) · Canadian Medical and Surgical Knowledge Translation Research Group (1) · Eastern Virginia Medical School (1) · Enzymotec (1) · Felizarta, Franco, M.D. (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Massachusetts General Hospital (1) · Rennes University Hospital (1) · Shanghai Jiao Tong University School of Medicine (1) · The University of Western Australia (1)
United States (7) · South Korea (4) · China (2) · Canada (1) · France (1) · Iran (1) · Israel (1) · Mexico (1)
Aaron I Vinik, MD, PhD (1) · Adrian S Dobs, MD (1) · Ana Polanco, MD (1) · David A Hess, PhD (1) · David Leaf, MD (1) · Deepak L Bhatt, MD, MPH (1) · Dick C Chan, PhD (1) · Dror Harats, M.D. (1) · Franco Felizarta, MD (1) · Gholamreza Sharifzadeh, M.S. (1) · Guang Ning, MD, PHD (1) · Henri K Parson, PhD (1)
PMID 19116237, PMID 19597368, PMID 19651918, PMID 19820283, PMID 20617456, PMID 20888102, PMID 22892157, PMID 23323877, PMID 23683266, PMID 25932792, PMID 38552629, PMID 39163858
K23AT002862 (1), R01DK061486 (1)