5 unknown, 4 completed. 4 Not applicable, 2 Phase 3, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Unknown 2 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 4 | 1 | Completed 1 |
Follow crocin: new trials by email Literature Review of crocin trials Research Report on crocin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Follow up Study of Crocin on Cardiac Function Protection in Patients With Breast Cancer Undergoing Neoadjuvant Chemotherapy Based on Color Doppler Ultrasound Combined With Myocardial Zymogram Crocin - Breast Cancer | Unknown | Mei Zhang | 120 | 2023-09-01 | 2024-01-03 | |
| Role of Saffron and Chamomile in the Management of Parkinson's Disease conventional therapy, Saffron and Chamomile, Crocin and Apigenin - Parkinson Disease, Neurodegenerative Diseases | Not applicable | Unknown | Jinnah Postgraduate Medical Centre | 120 | 2022-07-05 | 2023-01-25 |
| Efficacy of "Aquoral Lipo" Artificial Tears in Contact Lens Wearers With Discomfort Aquoral Lipo (Esteve), Hyabak (Thea) - Contact Lens Complication | Not applicable | Completed | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 41 | 2022-03-01 | 2024-10-08 |
| Crocin Supplementation in CSCR Crocin, Placebo - Chorioretinopathy, Central Serous | Phase 1 | Unknown | Shiraz University of Medical Sciences | 40 | 2021-07-01 | 2021-10-28 |
| Protection of Cardiovascular Function With Crocin in BrEast Cancer Patients Undergoing Radiotherapy and Chemotherapy crocin, Placebo - Breast Cancer | Not applicable | Unknown | Qilu Hospital of Shandong University | 120 | 2021-03-29 | 2022-09-22 |
| The Effects of Crocin Supplementation on Metabolic Parameters, Oxidative Stress, AMP- Activated Protein Kinase and Inflammation-promoting Genes Expression in Peripheral Blood Mononuclear Cells in Patients With Type 2 Diabetes crocin, placebo - Type 2 Diabetes | Not applicable | Completed | National Nutrition and Food Technology Institute | 50 | 2019-01-20 | 2019-11-15 |
| Evaluation Effect of Crocina on The Cellular Immune Responses in Osteoarthritis Patients Crocin, Placebo Oral Tablet - Osteoarthritis, Knee | Phase 3 | Unknown | Mashhad University of Medical Sciences | 40 | 2016-07-20 | 2017-12-18 |
| Platelet Transfusion for Treatment of Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates Liberal platelet transfusion, Restrictive platelet transfusion, Paracetamol - Patent Ductus Arteriosus | Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 44 | 2016-03-01 | 2018-04-06 |
| Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrome Saffron tablet, Barberry tablet, Placebo - Metabolic Syndrome, Hypercholesterolemia | Phase 4 | Completed | Birjand University of Medical Sciences | 732 | 2010-01-01 | 2012-06-21 |
Breast Neoplasms (2) · Central Serous Chorioretinopathy (1) · Diabetes Mellitus, Type 2 (1) · Ductus Arteriosus, Patent (1) · Hypercholesterolemia (1) · Hyperglycemia (1) · Hypertriglyceridemia (1) · Inflammation (1) · Metabolic Syndrome (1) · Neurodegenerative Diseases (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Parkinson Disease (1)
Birjand University of Medical Sciences (1) · Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA (1) · Jinnah Postgraduate Medical Centre (1) · Mashhad University of Medical Sciences (1) · Mei Zhang (1) · National Nutrition and Food Technology Institute (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Qilu Hospital of Shandong University (1) · Shiraz University of Medical Sciences (1)
Iran (4) · China (2) · India (1) · Pakistan (1) · Spain (1)
Fizzah Ali, MBBS,MPhil (1) · Gholamreza Sharifzadeh, M.S. (1) · Guoming Liu, master (1) · Javad Hadinia, B.S. (1) · Maryam Navabzadeh, M.D. (1) · Mei Zhang, PhD (1) · Mohammad Khodashenas Roudsari, M.D. (1) · Narges Saffari, B.S. (1) · Sourabh Dutta, MD (1) · Tayyebeh Kermani, Ph.D. (1) · Xinlei Zhang, master (1) · Xuena Zhao, master (1) · Yonghao Li, master (1) · Zhanpeng Zhao, master (1)
PMID 24904963, PMID 27706421, PMID 28389404, PMID 28951838, PMID 29147836, PMID 30159851, PMID 30940676, PMID 31111370, PMID 32670418, PMID 34224829, PMID 35274200, PMID 35822682, PMID 42253929