36 completed, 14 unknown, 6 recruiting, 3 not yet recruiting. 29 Not applicable, 5 Phase 2, 5 Phase 3, 4 Phase 1, 4 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR) Dehydrated Alcohol Injection, USP, Sham procedure - Hypertension, Hypertension,Essential | Phase 3 | Not yet recruiting | Ablative Solutions, Inc. | 202 | 2026-10-01 | 2026-08-20 |
| The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature IV Vitamin Infused Therapy Treatment, Herbal medicine - Anxiety Disorders and Symptoms, Fibromyalgia | Recruiting | Faith A. Richardson | 25 | 2025-12-21 | 2025-09-23 | |
| Engaging Home-monitored Assessment to Navigate Clinical Decision-making ENHANCe app, Teaching and training, Usual care - Hypertension,Essential | Not applicable | Enrolling by invitation | SingHealth Polyclinics | 116 | 2025-10-01 | 2026-02-10 |
| Treatment and Handling Severe Obesity-Related Comorbidities in Adolescents Through Exercise Treatment and handling obesity-related comorbidities in adolescents through exercise - Adolescent Obesity, Hypertension,Essential | Not applicable | Not yet recruiting | University of Lisbon | 24 | 2025-01-01 | 2024-07-29 |
| Food is Medicine vs Lifestyle Medicine For Cardiovascular Kidney Metabolic (CKM) Syndrome Lifestyle Medicine Program, Medically Tailored Groceries - Diabetes Mellitus, Metabolic Syndrome | Not applicable | Completed | Rutgers, The State University of New Jersey | 37 | 2024-10-12 | 2026-07-09 |
| Study of SGB-3908 in Healthy Subjects and Mildly Hypertensive Subjects SGB-3908, SGB-3908-Matching placebo - Hypertension,Essential | Phase 1 | Completed | Suzhou Sanegene Bio Inc. | 40 | 2024-07-31 | 2026-02-10 |
| Phase III Study to Evaluate the Efficacy and Safety of AD-209 AD-209, AD-2091, AD-209 Placebo - Hypertension,Essential | Phase 3 | Unknown | Addpharma Inc. | 280 | 2024-05-20 | 2024-05-21 |
| A Study to Evaluate the Efficacy and Safety of AD-224 AD-224A, AD-224B, AD-224C - Hypertension,Essential | Phase 3 | Completed | Addpharma Inc. | 254 | 2024-04-15 | 2026-08-03 |
| Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial Songling Xuemaikang Capsules, Lifestyle intervention, Placebo - Hypertension,Essential | Phase 4 | Recruiting | Xiyuan Hospital of China Academy of Chinese Medical Sciences | 100 | 2024-04-07 | 2024-08-20 |
| Endothelial Function in Prehypertension Hypertension,Essential | Not yet recruiting | Josip Juraj Strossmayer University of Osijek | 90 | 2024-04-01 | 2024-03-18 | |
| Safety, Tolerability, PK and PD of ADX-850 in Participants With Hypertension ADX-850, Placebo - Hypertension, Hypertension,Essential | Phase 1 | Active not recruiting | ADARx Pharmaceuticals, Inc. | 28 | 2024-03-21 | 2026-10-26 |
| A Study to Evaluate the Efficacy and Safety of AD-223 AD-223A, AD-223B, AD-223C - Hypertension,Essential | Phase 3 | Completed | Addpharma Inc. | 502 | 2024-02-15 | 2025-04-04 |
| Effect of Isometric and Aerobic Physical Exercise on Blood Pressure Levels in Hypertensive Elderly People Group control, Isometric Exercise, Aerobic Exercise - Hypertension,Essential, Hypertension | Not applicable | Unknown | Instituto de Cardiologia do Rio Grande do Sul | 36 | 2024-01-20 | 2024-02-28 |
| Effects of Electrical Nervous Stimulation Transcutaneous in Hypertensive Patients TENS - Cervical stimulation group, TENS - Plus cervical stimulation group, TENS - Renal stimulation group - Hypertension, Hypertension,Essential | Not applicable | Unknown | Federal University of Health Science of Porto Alegre | 40 | 2023-12-10 | 2023-11-30 |
| Licorice and Home Blood Pressure, Additional Study Licorice - Hypertension,Essential | Not applicable | Completed | Linkoeping University | 3 | 2023-09-19 | 2024-10-09 |
| Mobile Health Program for Rural Hypertension Coaching application, WebMD, Home-based blood pressure monitoring - Hypertension,Essential, Adherence, Medication | Not applicable | Recruiting | University of Pittsburgh | 334 | 2023-09-04 | 2025-11-19 |
| Functional Inspiratory Muscle Training in Patients Diagnosed With Hypertension Inspiratory muscle training with device - Hypertension,Essential | Not applicable | Completed | Mustafa Kemal University | 45 | 2023-05-01 | 2024-08-09 |
| Licorice and Home Blood Pressure Sweet licorice, Salty licorice - Hypertension,Essential | Not applicable | Completed | Linkoeping University | 28 | 2023-01-30 | 2023-08-28 |
| Health Expenses and Outcomes of the DASH Diet in Egyptian Patients With Hypertension DASH diet - Hypertension,Essential | Not applicable | Completed | Beni-Suef University | 364 | 2023-01-01 | 2024-07-12 |
| Efficacy and Safety Study of the Fixed-dose Combination of Olmesartan + Indapamide When Compared to the Isolated Drugs in the Treatment of Hypertension. fixed-dose of olmesartan 20mg/40 mg + indapamide 1,5 mg, Isolated drugs Olmesartan (20 mg or 40 mg) and Indapamide (1,5 mg) - Hypertension, Hypertension,Essential | Phase 3 | Unknown | Brainfarma Industria Química e Farmacêutica S/A | 400 | 2022-08-01 | 2022-03-21 |
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Essential Hypertension (62) · Hypertension (26) · Cardiovascular Diseases (5) · Metabolic Syndrome (4) · Motor Activity (3) · Obesity (3) · Diabetes Mellitus, Type 2 (2) · Hyperlipidemias (2) · Prehypertension (2) · Sleep Apnea, Obstructive (2) · Acquired Immunodeficiency Syndrome (1) · Anxiety Disorders (1) · Aortic Valve Stenosis (1) · Arthritis (1) · Atrial Fibrillation (1)
Vascular Diseases (62) · Cardiovascular Diseases (57) · Hypertension (36) · Pathological Conditions, Signs and Symptoms (13) · Pathologic Processes (7) · Nutritional and Metabolic Diseases (6) · Signs and Symptoms (6) · Behavior (4) · Body Weight (4) · Endocrine System Diseases (4) · Glucose Metabolism Disorders (4) · Hyperinsulinism (4) · Insulin Resistance (4) · Metabolic Diseases (4) · Nervous System Diseases (4)
Ethanol (2) · Glycyrrhiza glabra extract (2) · Losartan (2) · Acupuncture Therapy (1) · Adrenergic beta-Antagonists (1) · Amlodipine (1) · Antihypertensive Agents (1) · Aspirin (1) · Blood Specimen Collection (1) · Calcium Channel Blockers (1) · Captopril (1) · Chlorthalidone (1) · Continuous Positive Airway Pressure (1) · Control Groups (1) · Diet, Plant-Based (1)
Addpharma Inc. (4) · Ablative Solutions, Inc. (2) · Boryung Pharmaceutical Co., Ltd (2) · Linkoeping University (2) · ADARx Pharmaceuticals, Inc. (1) · Accumbo AB (1) · Aga Khan University (1) · Anil Nigam (1) · BackBeat Medical Inc (1) · Beata Krasinska (1) · Beijing Chao Yang Hospital (1) · Beni-Suef University (1) · Brainfarma Industria Química e Farmacêutica S/A (1) · Capital Medical University (1) · Centre Hospitalier Universitaire Vaudois (1)
China (10) · South Korea (8) · United States (7) · Sweden (4) · Australia (3) · Denmark (3) · Germany (3) · Italy (3) · Czechia (2) · France (2) · Singapore (2) · Argentina (1) · Belgium (1) · Brazil (1) · Canada (1)
Andrzej Tykarski, Prof (2) · Atul Pathak, Prof. (2) · MyungSook Hong (2) · Amir Kashani, MD, MPH (1) · Andreas Michalsen, Prof. Dr. (1) · Andrew Lynch, PT, PhD (1) · Anil Nigam, MD (1) · Ayeesha Kamal, MD (1) · Camilla Lundgreen Duus (1) · Chang Gyu Park, M.D., Ph.D (1) · ChangGu Park, M.D., Ph.D (1) · Changsheng Ma, Doctor (1) · Chi-Hang Lee, MD (1) · Chiara Lanzani, Doctor (1)
PMID 10450601, PMID 10678860, PMID 10908222, PMID 10940788, PMID 11010931, PMID 11208620, PMID 11422885, PMID 11454256, PMID 15867308, PMID 16376782, PMID 16960170, PMID 16960171, PMID 17494787, PMID 17921053, PMID 1798888, PMID 18404673, PMID 18458174, PMID 19482214, PMID 20016520, PMID 20411620, PMID 23069270, PMID 23317928, PMID 24048285, PMID 24107724, PMID 25469376, PMID 26208670, PMID 26307961, PMID 26363438, PMID 26781788, PMID 26840280, PMID 2698218, PMID 27388464, PMID 28122885, PMID 28290077, PMID 2936235, PMID 32958438, PMID 33484896, PMID 35420578, PMID 36094783, PMID 36517899, PMID 37035920, PMID 37258080, PMID 37295501, PMID 37747734, PMID 38172659, PMID 38242946, PMID 38246526, PMID 38458796, PMID 38588926, PMID 38632457
2018 (1), R01EY030564 (1), R01HL093238 (1), R01HL160749 (1)