42 completed, 8 unknown, 3 terminated, 2 active not recruiting. 58 Phase 2, 14 Phase 3, 8 Phase 1.
Follow Hyperlipidemia: new trials by email Literature Review of Hyperlipidemia trials Research Report on Hyperlipidemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Extension Study to Evaluate the Safety and Efficacy of HRS-7249 in Patients With Hypertriglyceridemia HRS-7249 Injection - Hyperlipidemia | Phase 2 | Recruiting | Fujian Shengdi Pharmaceutical Co., Ltd. | 400 | 2026-09-11 | 2026-10-09 |
| A Phase II Study To Evaluate the Efficacy And Safety Of HRS-1301 In Participants With Dyslipidemia HRS-1301, Placebo - Hyperlipidemia | Phase 2 | Recruiting | Shandong Suncadia Medicine Co., Ltd. | 189 | 2025-11-25 | 2025-12-12 |
| A Clinical Study Evaluating the Efficacy and Safety of HRS-7249 in Treating Patients With Hyperlipidemia HRS-7249 Injection, Sodium Chloride Injection - Hyperlipidemia | Phase 2 | Active not recruiting | Fujian Shengdi Pharmaceutical Co., Ltd. | 224 | 2025-08-12 | 2026-06-03 |
| Study on the Sex-specific, Lipid- and Lipoprotein-lowering Effects of Berberine Berberine, Placebo - Hyperlipidemia | Phase 2 / Phase 3 | Enrolling by invitation | The University of Hong Kong | 100 | 2024-08-01 | 2025-01-20 |
| Efficacy and Safety of SHR-1918 in Patients With Hyperlipidemia SHR-1918; SHR-1918 Placebo - Hyperlipidemia | Phase 2 | Completed | Beijing Suncadia Pharmaceuticals Co., Ltd | 44 | 2024-07-02 | 2026-02-05 |
| Whole Grain Job's Tear, Muscle Health, Blood Glucose and Lipid Level Taiwanese whole grain job's tear (red job's tear), White job's tear - Sarcopenia, Frailty | Phase 2 | Unknown | Taipei Veterans General Hospital, Taiwan | 80 | 2024-06-14 | 2024-07-16 |
| Effect of Nigella Sativa in Atorvastatin Treated Hyperlipidaemia Nigella Sativa capsule 500mg, Placebo - Hyperlipidemia | Phase 2 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 84 | 2023-08-24 | 2024-05-21 |
| Safety and Efficacy of CVI-LM001 in Patients With Hypercholesterolemia 100 mg, 200 mg, 300 mg - Hyperlipidemia | Phase 2 | Unknown | CVI Pharmaceuticals | 200 | 2020-07-15 | 2020-06-23 |
| The Safety, Tolerability and Efficacy of Multiple Subcutaneous Injections of SHR-1209 in Subjects With Hyperlipidemia SHR-1209, Placebo - Hyperlipidemia | Phase 1 / Phase 2 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 110 | 2019-06-20 | 2022-11-30 |
| Safety and Tolerability of VK2809 in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease VK2809, Placebo - Hyperlipidemia, NAFLD | Phase 2 | Completed | Viking Therapeutics, Inc. | 59 | 2016-09-28 | 2021-04-26 |
| A Comparative Study of Rosuvastatin and Atorvastatin in Patients With Hyperlipidemia Rosuvastatin, Atorvastatin - Hyperlipidemia | Phase 2 / Phase 3 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 90 | 2016-09-01 | 2016-12-02 |
| The Effect of Intranasal Insulin on Hepatic and Intestinal Triglyceride-rich Lipoprotein Production Insulin, Placebo - Hyperlipidemia | Phase 2 / Phase 3 | Completed | University Health Network, Toronto | 9 | 2016-04-14 | 2017-05-08 |
| A Study Of Pharmacokinetics, Pharmacodynamics And Safety Of Adding ETC-1002 To Atorvastatin 80 mg ETC-1002, Atorvastatin, Placebo - Hyperlipidemia | Phase 2 | Completed | Esperion Therapeutics, Inc. | 68 | 2015-12-01 | 2019-03-29 |
| The SCCS Polypill Pilot Trial Polypill (atorvastatin, amlodipine, losartan, and hydrochlorothiazide) - Hypertension, Hyperlipidemia | Phase 2 | Completed | Vanderbilt University | 303 | 2015-12-01 | 2021-05-14 |
| Evaluation of ARI-3037MO, to Suppress LDL Cholesterol in Patients With Dyslipidemia ARI-3037MO - Hyperlipidemia | Phase 2 | Unknown | Arisaph Pharmaceuticals Inc | 176 | 2015-08-01 | 2016-08-08 |
| Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy Metreleptin - Diabetes, Lipodystrophy | Phase 2 | Active not recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 29 | 2014-10-14 | 2026-10-27 |
| Efficacy and Safety of Kochujang Pills on Improvement of Blood Lipids Kochujang Pills, Placebo - Hyperlipidemia | Phase 2 / Phase 3 | Unknown | Chonbuk National University Hospital | 60 | 2012-11-01 | 2012-11-29 |
| Sitagliptin Regulation of Intestinal and Hepatic Lipoprotein Particle and Hepatic Glucose Production in Humans Sitagliptin, Placebo - Hyperlipidemia | Phase 2 / Phase 3 | Completed | University Health Network, Toronto | 21 | 2012-07-01 | 2017-01-23 |
| The Effect of Extract of Green Tea on Obese Women and Obese Related Hormone Peptides EGCG(Epigallocatechin Gallate), Placebo - Diabetes Mellitus, Hyperlipidemia | Phase 2 / Phase 3 | Unknown | Taipei City Hospital | 92 | 2012-05-01 | 2014-05-26 |
| A Single Center Study to Evaluate the Efficacy and Safety of ETC 1002 in Subjects With Type 2 Diabetes ETC-1002, Placebo - Hyperlipidemia, Type 2 Diabetes | Phase 2 | Completed | Esperion Therapeutics, Inc. | 60 | 2012-04-01 | 2019-03-29 |
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Hyperlipidemias (58) · Cardiovascular Diseases (8) · Hypercholesterolemia (6) · Diabetes Mellitus (5) · Hypertension (5) · Metabolic Syndrome (5) · HIV Infections (4) · Obesity (4) · Heart Diseases (3) · Hypercholesterolemia, Autosomal Dominant, 3 (3) · Insulin Resistance (3) · Patient Compliance (3) · Dyslipidemias (2) · Hyperglycemia (2) · Hypertriglyceridemia (2)
Nutritional and Metabolic Diseases (58) · Lipid Metabolism Disorders (57) · Metabolic Diseases (57) · Dyslipidemias (56) · Glucose Metabolism Disorders (13) · Pathological Conditions, Signs and Symptoms (10) · Signs and Symptoms (8) · Endocrine System Diseases (6) · Hyperinsulinism (6) · Body Weight (5) · Nutrition Disorders (5) · Overnutrition (5) · Urogenital Diseases (5) · Vascular Diseases (5) · Behavior (4)
Atorvastatin (10) · Ezetimibe (4) · Exercise (3) · Rosuvastatin Calcium (3) · evolocumab (3) · 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid (2) · Sodium Chloride (2) · (2-methyl-4-(5-methyl-2-(4-trifluoromethyl-phenyl)-2H-(1,2,3)triazol-4-ylmethylsulfanyl)phenoxy)acetic acid (1) · 2-((3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phenoxy)methyl)-4-(3-chlorophenyl)-2-oxido(1,3,2)dioxaphosphonane (1) · 6-(4'-trifluoromethyl-6-methoxybiphenyl-2-ylcarboxamido)-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid phenyl ester (1) · Acetylcholine (1) · Amlodipine (1) · BMS201038 (1) · Berberine (1) · Bradykinin (1)
University of Toronto (5) · Amgen (3) · Chonbuk National University Hospital (3) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (2) · Esperion Therapeutics, Inc. (2) · Fujian Shengdi Pharmaceutical Co., Ltd. (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · University Health Network, Toronto (2) · Aegerion Pharmaceuticals, Inc. (1) · Arisaph Pharmaceuticals Inc (1) · AstraZeneca (1) · Beijing Peking University WBL Biotech Co., Ltd. (1) · Beijing Suncadia Pharmaceuticals Co., Ltd (1) · CVI Pharmaceuticals (1) · Chestnut Hill Health System (1)
United States (27) · Canada (10) · China (7) · Denmark (4) · South Korea (3) · Australia (2) · Bangladesh (2) · Belgium (2) · Germany (2) · Hungary (2) · Iran (2) · Spain (2) · Taiwan (2) · Brazil (1) · Bulgaria (1)
David JA Jenkins, MD, PhD, DSc (2) · Abbas Delazar, PhD (1) · Akram Pourshams, PhD (1) · Ali Eskandari, MD (1) · Anchun Hwang, Doctor (1) · Angel Brea, MD (1) · Ann Melvin, MD (1) · Arshed A Quyyumi, MD (1) · Asim Ali Khan, MD (1) · Brian Roberts, M.D. (1) · Chung-Hua Hsu, PHD (1) · Cyril WC Kendall, PhD (1) · Dal-Sik Kim, MD (1)
PMID 22301925, PMID 25091629, PMID 12221048, PMID 18018771, PMID 18468736, PMID 19592624, PMID 20435205, PMID 21041432, PMID 21555712, PMID 21741606, PMID 21752880, PMID 21831304, PMID 21846904, PMID 22169113, PMID 22743313, PMID 23019316, PMID 23431291, PMID 23816039, PMID 23884353, PMID 24077434, PMID 24385236, PMID 24584549, PMID 24675657, PMID 24925526, PMID 24961447, PMID 25057276, PMID 25084280, PMID 25208075, PMID 25648989, PMID 25660356, PMID 25882384, PMID 26093535, PMID 28324110, PMID 28751575, PMID 31194872, PMID 31532959, PMID 33644749, PMID 33853731, PMID 35039035, PMID 38018702, PMID 38489667, PMID 40587053, PMID 42714362
M01RR000096 (1), M01RR000334 (1), R01HL057354 (1), R01HL079115 (1), R21AG023805 (1), R21DK053611 (1), U01AI068632 (1)