84 completed. 84 Phase 2, 13 Phase 1, 12 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 84 | Completed 84 |
| Phase 1 | 13 | Completed 13 |
| Phase 3 | 12 | Completed 12 |
Follow Hyperglycemia: new trials by email Literature Review of Hyperglycemia trials Research Report on Hyperglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Expanding Use of CGM in Critical Care: Impact on Nurse Work Patterns and Patient Outcomes Dexcom G6 - Hyperglycemia | Phase 1 / Phase 2 | Completed | Ohio State University | 201 | 2023-11-01 | 2026-02-06 |
| A Study to Evaluate Efficacy and Safety of Distal Jejunal-release Dextrose Beads Formulation in Subjects With a Pathological Oral Glucose Tolerance Test APHD-012, APH-012P - PreDiabetes, Glucose Tolerance Impaired | Phase 2 | Completed | Aphaia Pharma US LLC | 31 | 2023-03-31 | 2024-10-16 |
| Insulin and Abatacept in Recently-diagnosed Type 1 Diabetes Abatacept (CTLA4-Ig) and nasal insulin (Humulin R®), Abatacept (CTLA4-Ig) and nasal placebo (0.9% sodium chloride) - Type 1 Diabetes, Diabetes Mellitus, Type 1 | Phase 2 | Completed | Melbourne Health | 68 | 2023-02-13 | 2025-12-24 |
| The Metabolic Effects of Empagliflozin in Patients With High Risk of Heart Failure Empagliflozin 10 MG, Placebo - Obesity, Heart Failure | Phase 2 | Completed | Jacob Moller | 165 | 2021-09-02 | 2025-01-29 |
| SGLT2 Inhibitor Effects on Inflammation and Heart Disease in Obesity Pilot Empagliflozin 25 MG - Obesity, Pre-diabetes | Phase 1 / Phase 2 | Completed | Vanderbilt University Medical Center | 29 | 2021-07-29 | 2023-12-29 |
| Phentermine/Topiramate for Uric Acid Stones Phentermine / Topiramate Oral Product, Citrate Salts, Allopurinol, Diet - Obesity, Uric Acid Stones | Phase 2 | Completed | University of Florida | 19 | 2021-03-31 | 2026-06-15 |
| HSK7653 in Chinese Patients with Impaired Glucose Tolerance HSK7653 10mg Q2W, HSK7653 25mg Q2W, Placebo - Impaired Glucose Tolerance | Phase 2 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 99 | 2021-03-29 | 2024-11-25 |
| Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity Hyperinsulemic euglycemic clamp, Muscle Biopsy, Oral abscisic acid (ABA) - Pre Diabetes | Phase 2 | Completed | AdventHealth Translational Research Institute | 5 | 2021-03-08 | 2026-03-09 |
| Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients Alpelisib, Metformin, Fulvestrant - Breast Cancer | Phase 2 | Completed | MedSIR | 69 | 2020-10-23 | 2025-07-29 |
| SGLT2 Inhibition in Older Obese Adults With Pre-diabetes Dapagliflozin 10 mg, Nutritional counseling - Aging | Phase 1 / Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 20 | 2020-06-25 | 2024-01-05 |
| Type 2 Diabetes Mellitus Prevention Ukraine Physical activity, Macronutrient modification - Impaired Fasting Glucose, Impaired Glucose Tolerance | Phase 2 | Completed | Komisarenko Institute of Endocrinology and Metobolism | 30 | 2020-02-20 | 2022-08-26 |
| Inositol Supplementation to Treat PCOS (INSUPP-PCOS) Placebo, Inositol - Polycystic Ovary Syndrome, Anovulation | Phase 2 | Completed | Milton S. Hershey Medical Center | 154 | 2020-01-24 | 2026-10-28 |
| Assess the Efficacy and Safety of Exenatide SR for the Prevention of Diabetes After Kidney Transplantation Exenatide SR - Pre Diabetes | Phase 2 | Completed | Mayo Clinic | 9 | 2019-05-09 | 2022-10-28 |
| Safety and Feasibility Evaluation of the APS APP Artificial Pancreas App - Type 1 Diabetes Mellitus | Phase 2 / Phase 3 | Completed | Sansum Diabetes Research Institute | 6 | 2018-02-28 | 2018-09-05 |
| A Phase II Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula Lanreotide Prefilled Syringe - Pancreatic Leak, Pancreatic Fistula | Phase 2 | Completed | University of Washington | 114 | 2018-02-20 | 2022-06-16 |
| Exenatide Once Weekly for Smoking Cessation Exenatide, NRT, Counseling - Smoking Cessation | Phase 1 / Phase 2 | Completed | The University of Texas Health Science Center, Houston | 84 | 2016-07-01 | 2021-01-28 |
| Effect of Gymnema Sylvestre on Patients With Impaired Glucose Tolerance. Gymnema Sylvestre, Placebo - Impaired Glucose Tolerance | Phase 2 | Completed | University of Guadalajara | 30 | 2016-03-01 | 2021-02-02 |
| Effect of Chlorogenic Acid on Patients With Impaired Glucose Tolerance Placebo, Chlorogenic acid - Impaired Glucose Tolerance | Phase 2 | Completed | University of Guadalajara | 30 | 2015-09-01 | 2019-08-02 |
| BTI320 (SUGARDOWN®) on Post-Prandial Hyperglycaemia in Subjects With Pre-Diabetes BTI320, BTI320 matching placebo - Pre-Diabetes | Phase 2 | Completed | Chinese University of Hong Kong | 60 | 2015-03-30 | 2017-04-25 |
| Metformin to Augment Low Milk Supply (MALMS) Study Standard care, Metformin, Placebo - Low Milk Supply, Pre-diabetes | Phase 1 / Phase 2 | Completed | Children's Hospital Medical Center, Cincinnati | 15 | 2014-06-01 | 2020-10-19 |
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Glucose Intolerance (53) · Obesity (17) · Diabetes Mellitus, Type 2 (16) · Insulin Resistance (16) · Diabetes Mellitus (13) · Metabolic Syndrome (12) · Hypertension (6) · Hypoglycemia (5) · Prediabetic State (5) · Diabetes Mellitus, Type 1 (4) · Heart Failure (4) · Obesity, Abdominal (4) · Overweight (4) · Cardiovascular Diseases (3)
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Metformin (7) · Insulin (6) · Diet (4) · Exenatide (4) · Exercise (4) · Pioglitazone (4) · Rosiglitazone (3) · Sitagliptin Phosphate (3) · Standard of Care (3) · 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid (2) · Cholecalciferol (2) · Genistein (2) · Quercetin (2) · Vildagliptin (2) · canakinumab (2)
National Heart, Lung, and Blood Institute (NHLBI) (3) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Genfit (2) · Kathleen Dungan (2) · Marcus Saemann (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Novartis Pharmaceuticals (2) · University of Guadalajara (2) · University of Messina (2) · AdventHealth Translational Research Institute (1) · Albert Einstein College of Medicine (1) · Anhui Medical University (1) · Aphaia Pharma US LLC (1) · Arete Therapeutics (1) · Assistance Publique - Hôpitaux de Paris (1)
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