4 completed, 2 terminated, 1 recruiting, 1 unknown. 8 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 4, Terminated 2, Recruiting 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
Follow Hypercalciuria: new trials by email Literature Review of Hypercalciuria trials Research Report on Hypercalciuria
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Fluconazole in Hypercalcicuric Patients With Increased 1.25(OH) 2D Levels Fluconazole, Placebo - Nephrolithiasis, Nephrocalcinosis | Phase 2 | Completed | Hospices Civils de Lyon | 56 | 2021-01-13 | 2024-07-12 |
| Safety and Efficacy of Chlorthalidone in Type 1 Diabetes Chlorthalidone - Type 1 Diabetes Mellitus, Hypercalciuria | Phase 2 | Terminated | University of Rochester | 1 | 2019-06-28 | 2021-01-05 |
| Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria Rifampin - Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease | Phase 2 | Recruiting | Children's Hospital of Philadelphia | 60 | 2018-07-25 | 2026-10-13 |
| Recombinant Human rhPTH(1-34) VS Association Alfacalcidol/Hydrochlorothiazide in Severe Primary Hypoparathyroidism Teriparatide, Thiazide, Potassium sparing diuretic - Autosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under Treatment | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 16 | 2017-06-06 | 2021-06-28 |
| ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study ACTHAR Gel (adrenocorticotropic hormone) - Sarcoidosis, Hypercalcemia Due to Sarcoidosis | Phase 2 / Phase 3 | Unknown | Albany Medical College | 10 | 2015-02-01 | 2015-01-26 |
| The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass Transdermal estradiol - Hypercalciuria, Hypercalciuria, Familial Idiopathic | Phase 2 | Terminated | University of Chicago | 1 | 2013-08-01 | 2018-12-10 |
| Treatment for Calcium Phosphate Kidney Stone Disease Placebo, Citric Acid, Potassium Citrate - Calcium Phosphate Kidney Stones | Phase 2 | Completed | University of Texas Southwestern Medical Center | 13 | 2012-07-01 | 2024-04-04 |
| Low Salt Diet in Idiopathic Hypercalciuria Low salt diet, Water therapy alone - Hypercalciuria | Phase 2 / Phase 3 | Completed | University of Parma | 210 | 2005-01-01 | 2009-10-30 |
Nephrocalcinosis (3) · Hypercalcemia (2) · Nephrolithiasis (2) · Bone Diseases, Metabolic (1) · Diabetes Mellitus, Type 1 (1) · Genetic Diseases, Inborn (1) · Glomerulonephritis (1) · Hypercalcemia, Idiopathic, of Infancy (1) · Hypercalciuria, Absorptive, 2 (1) · Hypercalciuric Hypercalcemia (1) · Hypoparathyroidism (1) · Kidney Calculi (1) · Nephritis, Interstitial (1) · Osteoporosis (1)
Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (8) · Urological Manifestations (8) · Metabolic Diseases (5) · Nutritional and Metabolic Diseases (5) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Kidney Diseases (4) · Male Urogenital Diseases (4) · Urogenital Diseases (4) · Urologic Diseases (4) · Calcinosis (3) · Calcium Metabolism Disorders (3) · Endocrine System Diseases (2) · Immune System Diseases (2)
Adrenocorticotropic Hormone (1) · Amiloride (1) · Chlorthalidone (1) · Citric Acid (1) · Diet, Sodium-Restricted (1) · Estradiol (1) · Fluconazole (1) · Hydrochlorothiazide (1) · Potassium Citrate (1) · Rifampin (1) · Sodium Channel Blockers (1) · Teriparatide (1) · Thiazides (1) · Water (1) · alfacalcidol (1)
Albany Medical College (1) · Assistance Publique - Hôpitaux de Paris (1) · Children's Hospital of Philadelphia (1) · Hospices Civils de Lyon (1) · University of Chicago (1) · University of Parma (1) · University of Rochester (1) · University of Texas Southwestern Medical Center (1)
United States (5) · France (2) · Italy (1)
Agnes Linglart, MD, PhD (1) · Anne Blanchard, MD, PhD (1) · Marc A Judson, MD (1) · Michael A Levine, MD (1) · Murray J Favus, MD (1) · Naim M Maalouf, MD (1)
2016 (1), K23DK114477 (1), R01DK112955 (1), R21DK097476 (1)