3 completed, 3 unknown, 1 not yet recruiting, 1 terminated. 3 Phase 3, 2 Not applicable, 2 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 2, Not yet recruiting 1 |
| Not applicable | 2 | Unknown 2 |
| Phase 4 | 2 | Terminated 1, Withdrawn 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Hyperactive Delirium: new trials by email Literature Review of Hyperactive Delirium trials Research Report on Hyperactive Delirium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phenobarbital for Agitated Delirium Phenobarbital, Conventional therapy group - Agitated Delirium, Delirium Confusional State | Phase 3 | Not yet recruiting | Duke University | 150 | 2026-06-01 | 2026-04-23 |
| Effects of Dexmedetomidine in Patients With Agitated Delirium in Palliative Care Dexmedetomidine Hydrochloride - Hyperactive Delirium, Delirium of Mixed Origin | Phase 1 / Phase 2 | Unknown | Bruyère Health Research Institute. | 50 | 2024-01-30 | 2025-04-15 |
| Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium Quatiapine, Haloperidol - Hyperactive Delirium | Phase 3 | Completed | Alexandria University | 100 | 2023-04-09 | 2023-08-30 |
| Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium Valproate, Quetiapine, Standard of Care - Covid19, Hyperactive Delirium | Phase 4 | Withdrawn | University of Miami | 2023-03-28 | 2023-03-31 | |
| HALO Trial: Haloperidol vs Olanzapine in Hyperactive Delirium in Palliative Care Patients; A Multi-Centre, Randomised-Controlled Trial Haldol 2mg/ml oral solution, Olanzapine Actavis 5mg orodispersible tablet - Haloperidol, Advanced Cancer | Phase 3 | Completed | Tan Tock Seng Hospital | 22 | 2022-05-18 | 2026-10-05 |
| MindfulGarden in Treatment of Hyperactive Delirium in a Hospital Setting MindfulGarden - Hyperactive Delirium | Not applicable | Unknown | Simon Fraser University | 24 | 2018-09-01 | 2018-08-13 |
| Delirium Prevention in Patients From the Intensive Care Unit (DELA) Delirium prevention program - Hypoactive Delirium, Hyperactive Delirium | Not applicable | Unknown | Universidad de Santander | 200 | 2017-10-01 | 2017-10-27 |
| Valproic Acid for Treatment of Hyperactive or Mixed Delirium in ICU Valproic Acid, Placebo, Haloperidol - Hyperactive Delirium, Mixed Delirium | Phase 4 | Terminated | Stanford University | 3 | 2015-01-01 | 2019-06-26 |
| A Pilot Study of "Stanford Proxy Test for Delirium" (S-PTD) Hyperactive Delirium, Hypoactive Delirium | Completed | Stanford University | 300 | 2014-02-01 | 2019-05-17 |
Delirium (4) · Aggression (1) · Anxiety Disorders (1) · COVID-19 (1) · Confusion (1) · Death (1) · Pneumonia, Viral (1) · Psychomotor Agitation (1) · Spasm (1)
Nervous System Diseases (5) · Neurobehavioral Manifestations (5) · Neurologic Manifestations (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Confusion (4) · Mental Disorders (4) · Neurocognitive Disorders (4) · Aberrant Motor Behavior in Dementia (2) · Behavior (2) · Behavioral Symptoms (2) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Dyskinesias (1) · Infections (1)
Haloperidol (3) · Valproic Acid (2) · Dexmedetomidine (1) · Phenobarbital (1) · Quetiapine Fumarate (1) · Solutions (1) · Standard of Care (1)
Stanford University (2) · Alexandria University (1) · Bruyère Health Research Institute. (1) · Duke University (1) · Simon Fraser University (1) · Tan Tock Seng Hospital (1) · Universidad de Santander (1) · University of Miami (1)
United States (3) · Canada (1) · Colombia (1) · Egypt (1) · Singapore (1)
Jose R Maldonado, M.D. (2) · Claudia C Torres, RN, MSc (1) · Dominique L Musselman, MD (1) · Gloria Gutman (1) · Ibrahim K. Luttfi, PHD (1) · Islam E. Ahmed, PharmD (1) · James Downar, MDCM, MSc (1) · Keith W. Van Dusen, M.D. (1) · Mervyn Koh (1) · Tamer N. Habib, MD (1) · Yelizaveta Sher, M.D. (1)