21 unknown, 20 completed, 8 recruiting, 5 not yet recruiting. 39 Not applicable, 2 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 39 | Unknown 15, Completed 13, Not yet recruiting 4, Active not recruiting 3, Recruiting 2, Terminated 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 4 | 2 | Completed 2 |
Follow High Myopia: new trials by email Literature Review of High Myopia trials Research Report on High Myopia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Spectacle Lenses With H.A.L.T. MAX Technology on High Myopia Control in Children and Adolescents H.A.L.T. MAX spectacles - Myopia, High Myopia | Not applicable | Withdrawn | Shanghai Eye Disease Prevention and Treatment Center | 2026-10-30 | 2026-11-02 | |
| SmoothCore Orthokeratology Plus M.O.V.E. Lenses vs. M.O.V.E. Lenses Alone for Myopia Control in Children With High Myopia SmoothCore Technology Orthokeratology Combined with M.O.V.E. Lenses, M.O.V.E. Lenses Alone - High Myopia | Not applicable | Not yet recruiting | Beijing Tongren Hospital | 100 | 2026-10-08 | 2026-10-16 |
| Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy. blood sampling for DNA - High Myopia | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 200 | 2026-02-12 | 2026-08-07 |
| Visual Outcomes of an Enhanced Monofocal Intraocular Lens Targeted for Monovision in Highly Myopic Eyes: a Randomized Controlled Trial Enhanced monofocal intraocular lens implantation (monovision strategy), Enhanced monofocal intraocular lens implantation (bilateral myopia strategy) - Cataract, High Myopia | Not applicable | Not yet recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 66 | 2025-10-01 | 2025-09-18 |
| 100 High Myopia Patient-reported Outcomes (PRO) and Performance Outcomes (PERFO) Quality of life questionnaire, Performance Outcomes (PerfO), Semi-structured interviews - High Myopia | Not applicable | Not yet recruiting | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts | 100 | 2025-10-01 | 2025-08-03 |
| Comparison of Retinal Damage in ICL Implantation Using 3D Visualization System vs. Microscope 3D visualization system with coaxial illumination, microscope with standard illumination - High Myopia | Not applicable | Not yet recruiting | Fuzhou Eye Hospital | 40 | 2025-08-25 | 2025-08-08 |
| The Role of Capsular Tension Rings in Intraocular Lens Stability in High Myopia Cataract Patients: A Prospective Self-Controlled Study CTR implantation - High Myopia, Cataract | Not applicable | Recruiting | Jin Yang | 120 | 2025-01-01 | 2025-07-07 |
| Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging pentacam scheimpflug tomography - Keratoconus, High Myopia | Not yet recruiting | Assiut University | 66 | 2024-12-01 | 2024-12-18 | |
| AI-Empowered Fundus Platform Multimodal Ocular Imaging and Biometry with Aritifical Intelligence Analysis - High Myopia | Recruiting | Shanghai 10th People's Hospital | 1000 | 2024-10-01 | 2026-02-20 | |
| Evaluation of Retinal Vascular Density in High Myopia Without Pathological Myopic Maculopathy Using OCTA . optical coherence tomography angiography - High Myopia | Not applicable | Unknown | Sohag University | 50 | 2024-09-11 | 2024-09-19 |
| 3D Visualization System in Highly Myopic Cataract Operation Alcon-NGENUITY®(NG)-system, Standard cataract operation - Cataract, High Myopia | Not applicable | Completed | National Taiwan University Hospital | 40 | 2024-07-03 | 2026-08-19 |
| Evaluation of Eye Health Benefits of Black Tomato Extract Black tomato extract powder, Placebo powder - Eye, High Myopia | Not applicable | Completed | TCI Co., Ltd. | 56 | 2024-04-01 | 2025-06-13 |
| Wuhan High Myopia Study observational - High Myopia | Recruiting | Renmin Hospital of Wuhan University | 1000 | 2023-12-25 | 2023-12-27 | |
| Effect of Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation on Macular Sensitivity in Patients With High Myopia Lutein + meso-zeaxanthin + zeaxanthin (LMZ) - High Myopia | Phase 2 | Completed | Asociación para Evitar la Ceguera en México | 70 | 2023-12-14 | 2026-11-10 |
| Efficacy and Safety of Low-Level Monochromatic Red-Light for High Myopia Control in Adults Myopic amblyopia comprehensive treatment instrument, Glasses - High Myopia | Not applicable | Unknown | Shanghai Eye Disease Prevention and Treatment Center | 60 | 2023-08-01 | 2023-07-14 |
| Low Concentration Atropine Combined With Soft Contact Lens in Controlling Myopia Progression in Children With High Myopia soft peripheral defocus contact lenses, Atropine 0.04%, Atropine (0.01%) - High Myopia, Low Concentration Atropine | Phase 4 | Completed | Beijing Tongren Hospital | 120 | 2023-06-30 | 2026-02-12 |
| Effect of IOP Lowering on Progressive HM Assigned Interventions: IOP-lowering eye drops - High Myopia, Intraocular Pressure | Not applicable | Active not recruiting | Sun Yat-sen University | 152 | 2023-06-01 | 2026-11-05 |
| Screening and Identification of Biomarkers for High Myopia by a Rapid Method blood sample - High Myopia | Unknown | Beijing Tongren Hospital | 120 | 2023-03-20 | 2023-04-07 | |
| Repeated Low-Level Red-Light Therapy Shortens Axial Length RLRL - High Myopia, Axial Length | Not applicable | Unknown | The Second People's Hospital of Foshan | 30 | 2023-03-01 | 2023-03-14 |
| Repeated Low-Level Red-Light Therapy for Shortening Axial Length RLRL - High Myopia, Refractive Errors | Not applicable | Active not recruiting | Shanghai Eye Disease Prevention and Treatment Center | 30 | 2022-11-19 | 2025-03-30 |
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Cataract (9) · Myopia (6) · Retinal Perforations (3) · Eye Diseases (2) · Refractive Errors (2) · Retinal Detachment (2) · Anisometropia (1) · Anticipation, Genetic (1) · Astigmatism (1) · Glaucoma, Open-Angle (1) · Hyperopia (1) · Keratoconus (1) · Macular Degeneration (1) · Ocular Hypertension (1) · Ocular Hypotension (1)
Eye Diseases (28) · Lens Diseases (9) · Refractive Errors (8) · Retinal Diseases (5) · Pathological Conditions, Signs and Symptoms (2) · Retinal Degeneration (2) · Avitaminosis (1) · Behavior (1) · Corneal Diseases (1) · Deficiency Diseases (1) · Disease Attributes (1) · Disease Susceptibility (1) · Genetic Predisposition to Disease (1) · Glaucoma (1) · Malnutrition (1)
Vitrectomy (3) · Atropine (2) · Blood Specimen Collection (2) · Cataract Extraction (2) · Watchful Waiting (2) · Caffeine (1) · Corneal Topography (1) · DNA (1) · Eyeglasses (1) · Gases (1) · Lutein (1) · Photorefractive Keratectomy (1) · Tomography, Optical Coherence (1) · Vitamin E (1) · Zeaxanthins (1)
Shanghai Eye Disease Prevention and Treatment Center (7) · Sun Yat-sen University (6) · National Taiwan University Hospital (5) · Beijing Tongren Hospital (4) · Assiut University (3) · Wenzhou Medical University (3) · Shanghai High Myopia Study Group (2) · The Hong Kong Polytechnic University (2) · Zhongshan Ophthalmic Center, Sun Yat-sen University (2) · Asociación para Evitar la Ceguera en México (1) · Assistance Publique - Hôpitaux de Paris (1) · Baylor College of Medicine (1) · Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (1) · Ege University (1) · Evidence Based Cataract Study Group (1)
China (34) · Taiwan (5) · Egypt (3) · France (2) · Hong Kong (2) · Germany (1) · Japan (1) · Mexico (1) · United States (1)
Jin Yang (2) · Lin Lu, MD，PhD (2) · Tzyy-Chang Ho (2) · Xiulan Zhang, MD, PhD (2) · AYong Yu, MD.PhD. (1) · Adham Salah Mohammed, lecturer (1) · Belquiz A Nassaralla (1) · Chung-May Yang, MD (1) · Evelyn Paysse, MD (1) · Fenghua Wang (1) · Guillermo Salcedo Villanueva, MD (1) · He Jiangnan, PhD (1)
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