10 unknown, 8 recruiting, 5 completed, 3 not yet recruiting. 13 Not applicable, 5 Phase 4, 3 Phase 2, 2 Phase 3.
Follow Heart Failure Acute: new trials by email Literature Review of Heart Failure Acute trials Research Report on Heart Failure Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Simulation-Based Cardiac Point-of-Care Ultrasound Program to Improve Clinical Outcomes in Acute Heart Failure Patients Simulation POCUS training, Clinical Practice Guidelines - Heart Failure Acute, Point-of-care Ultrasound | Not applicable | Not yet recruiting | Duke University | 175 | 2026-09-01 | 2026-05-18 |
| Contrast-Induced Acute Kidney Injury Prevention in Acute Heart Failure Furosemide, 0.9 % Normal Saline - Heart Failure Acute, Renal Dysfunction | Not applicable | Recruiting | Jin Joo Park | 190 | 2026-07-01 | 2026-07-16 |
| Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure Furosemide intravenous solution - Heart Failure, Heart Failure - NYHA II - IV | Phase 4 | Recruiting | Lakeland Regional Health Systems, Inc. | 600 | 2026-04-01 | 2026-04-09 |
| Vexus Assessment and Natriuresis-guided Diuretic Therapy in Acute Heart Failure Natriuresis-guided escalation of loop diuretics - Venous Congestion, Heart Failure Acute | Not applicable | Not yet recruiting | University Hospital, Akershus | 270 | 2026-04-01 | 2026-04-30 |
| Continuous Remote ECG Monitoring to Predict 30-day Outcome After Hospital Discharge in Patients With Heart Failure : A Pilot Study Using a New Wearable Sensor ECG Monitoting - Heart Failure Acute, Telemonitoring | Active not recruiting | University of Monastir | 50 | 2026-01-01 | 2026-07-13 | |
| Congestion and LActate at diScHarge in Acute Heart Failure Lung Ultrasound Score, Lactate Blood Test - Heart Failure Acute, Discharge Follow-up Phone Calls | Recruiting | University of Monastir | 350 | 2026-01-01 | 2026-07-15 | |
| Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers Cardiac point-of-care ultrasound (POCUS) training and clinical pathway - Cardiovascular Disease Acute, Emergency Department Patient | Not applicable | Recruiting | Duke University | 75 | 2025-11-13 | 2026-06-03 |
| Evaluation of the Effectiveness of the CardioStory Device in Distinguishing Heart Failure From Other Causes in Patients Presenting With Dyspnea cardiostory - Dyspnea, Heart Failure Acute | Withdrawn | Hôpital Universitaire Sahloul | 2025-09-01 | 2026-09-30 | ||
| SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF Dapagliflozin tablet, Hypertonic Saline Solution, 1 Ml, Furosemide Injection - Heart Failure Acute, Diabetes Type 2 | Phase 4 | Unknown | University of Palermo | 544 | 2024-06-01 | 2024-06-06 |
| Acetazolamide or Metolazone in Acute Heart Failure Acetazolamide 250 MG, Metolazone 2.5 MG, Furosemide Injection - Heart Failure Acute, Decompensated Heart Failure | Not applicable | Not yet recruiting | Clinica Alemana de Santiago | 1050 | 2024-05-01 | 2024-03-18 |
| Prediction of Heart-Failure with Machine Learning Monitoring with Apple Watch - Heart Failure with Reduced Ejection Fraction, Heart Failure | Recruiting | University Medical Center Goettingen | 32 | 2024-04-01 | 2025-02-11 | |
| Prognostic Model Heart Failure Acute Heart Failure - Heart Failure Acute | Unknown | National Institute of Cardiovascular Diseases, Pakistan | 1000 | 2024-02-14 | 2024-05-16 | |
| Remote Monitoring After Heart Failure Nurse-led remote monitoring program, Usual care treatment - Heart Failure Acute, Remote Monitoring | Not applicable | Active not recruiting | Vestre Viken Hospital Trust | 200 | 2023-04-25 | 2025-10-01 |
| Investigating a Tailored Diuretic Algorithm in Acute Heart Failure Patients Urine sodium guided diuretic algorithm, Usual care - Heart Failure Acute | Not applicable | Recruiting | Zuyderland Medisch Centrum | 556 | 2023-02-27 | 2026-04-13 |
| Lesser Poland Cracovian Heart Failure Registry Heart Failure, Heart Failure Acute | Recruiting | Jagiellonian University | 2500 | 2023-02-15 | 2024-03-06 | |
| SGLT2 Inhibitors in Patients With ADHF During Ventilator Weaning SGLT2 inhibitor - Heart Failure Acute, Ventilator Lung | Phase 3 | Recruiting | National Taiwan University Hospital | 450 | 2022-10-10 | 2023-11-21 |
| The SWISSHEART Failure Network (SHFN) Heart Failure Acute, Acute Myocardial Infarction | Unknown | University of Zurich | 8000 | 2021-11-01 | 2022-12-09 | |
| Evaluation and Support Care Process Within the Care Pathway of Heart Failure Patients Conventional hospitalization, FIL-EAS ic care pathway - Heart Failure Acute | Not applicable | Completed | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 361 | 2021-06-28 | 2026-07-07 |
| Pragmatic Urinary Sodium-based Treatment algoritHm in Acute Heart Failure Natriuresis - Heart Failure Acute | Not applicable | Completed | University Medical Center Groningen | 310 | 2021-02-01 | 2024-04-22 |
| Development and Validation of a Simple-to-use Nomogram for Predicting In-hospital Mortality in Acute Heart Failure Patients Undergoing Continuous Renal Replacement Therapy no intervention - Heart Failure Acute | Unknown | Qilu Hospital of Shandong University | 226 | 2020-10-30 | 2021-02-12 |
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Heart Failure (16) · Pulmonary Edema (2) · Cardiac Tamponade (1) · Cardio-Renal Syndrome (1) · Cardiovascular Diseases (1) · Diabetes Mellitus, Type 2 (1) · Disease (1) · Dyspnea (1) · Edema (1) · Heart Failure, Diastolic (1) · Heart Failure, Systolic (1) · Hyperemia (1) · Pericardial Effusion (1) · Pulmonary Embolism (1) · Renal Insufficiency (1)
Heart Diseases (17) · Cardiovascular Diseases (16) · Respiratory Tract Diseases (4) · Lung Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Signs and Symptoms (2) · Urogenital Diseases (2) · Urologic Diseases (2) · Vascular Diseases (2) · Diabetes Mellitus (1) · Embolism (1)
Furosemide (5) · Metolazone (3) · Sodium-Glucose Transporter 2 Inhibitors (2) · dapagliflozin (2) · empagliflozin (2) · Acetazolamide (1) · Chlorothiazide (1) · Critical Pathways (1) · Echocardiography (1) · Methods (1) · Natriuresis (1) · Nitrates (1) · Noninvasive Ventilation (1) · Practice Guidelines as Topic (1) · Saline Solution (1)
Duke University (2) · Indiana University (2) · NeuroTronik Inc. (2) · University Medical Center Groningen (2) · University of Monastir (2) · A.O.U. Città della Salute e della Scienza (1) · Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer (1) · Clinica Alemana de Santiago (1) · Hillel Yaffe Medical Center (1) · Hôpital Universitaire Sahloul (1) · Jagiellonian University (1) · Jin Joo Park (1) · Laikο General Hospital, Athens (1) · Lakeland Regional Health Systems, Inc. (1) · National Institute of Cardiovascular Diseases, Pakistan (1)
United States (7) · Netherlands (3) · Norway (2) · South Korea (2) · Tunisia (2) · China (1) · France (1) · Germany (1) · Greece (1) · Israel (1) · Italy (1) · Pakistan (1) · Panama (1) · Paraguay (1) · Poland (1)
Peter S Pang, MD (2) · Adriaan Voors, Prof. Dr. (1) · Anas Bizanti, MD (1) · Andrew Lurie, DO (1) · Brent Reed, PharmD (1) · Christian M Matter, MD (1) · Giuseppe Miceli, PhD (1) · Goo-Yeong Cho, MD, PhD (1) · Jadwiga Nessler, Prof. (1) · Jin Joo Park, MD, PhD (1) · John Barbetseas, MD (1) · Karina Zilber, MD (1) · Madiha Fatima, MBBS, FCPS (1)
PMID 15963399, PMID 20607462, PMID 21440872, PMID 21885793, PMID 22980301, PMID 26240596, PMID 30448355, PMID 32139695, PMID 32709292, PMID 32970396, PMID 34246609, PMID 34447992, PMID 34612019, PMID 35001562, PMID 35241246, PMID 36607775, PMID 37640861, PMID 39513018, PMID 41893376, PMID 42018019
2017 (1), R03AG064371 (1)