14 completed, 4 terminated, 4 unknown, 3 withdrawn. 9 Not applicable, 4 Phase 2, 4 Phase 3, 2 Phase 1, 1 Early Phase 1.
Follow Heart Decompensation: new trials by email Literature Review of Heart Decompensation trials Research Report on Heart Decompensation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Social Prescribing to Improve Adherence and Outcomes in Women With Heart Failure Social prescribing - Heart Failure, Cardiac Failure | Not applicable | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 200 | 2025-10-23 | 2026-02-20 |
| COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C - Cardiopulmonary Failure, Myocardial Infarction (MI) | Enrolling by invitation | Peerbridge Health, Inc | 15000 | 2024-11-16 | 2025-01-08 | |
| Acquisition of Cardiac Function Parameters in MRI and Echocardiography in Patients With Ethyltoxic Liver Cirrhosis and Transjugular Intrahepatic Portosystemic Shunt (TIPSS) Placement Cardiac MRI, Blood samples, Echocardiography - MASLD, Liver Cirrhosis, Alcoholic | Not applicable | Recruiting | Stephanie Gräger | 80 | 2024-04-19 | 2026-08-04 |
| Multiparametric Assessment of Cardiac Congestion in Outpatient Worsening Heart Failure Observational study - Heart Failure, Heart Decompensation | Completed | Corteria Pharmaceuticals | 42 | 2022-09-28 | 2024-02-13 | |
| RAndomized Controlled Trial of a Multiple INtervention proGram to Decrease Heart Failure Rehospitalization Multiple intervention program - Heart Decompensation | Not applicable | Terminated | French Cardiology Society | 25 | 2022-07-15 | 2024-10-04 |
| Comparison of PEEP in Acute Decompensated Heart Failure PEEP - Heart Decompensation, Mechanical Ventilation Pressure High | Not applicable | Unknown | Asan Medical Center | 120 | 2021-04-20 | 2022-02-23 |
| Evaluating the Adherence Improving Self-Management Strategy Intervention in Chronic Heart Failure Patients Adherence Improving self-Management Strategy, Treatment-as-usual - Chronic Heart Failure, Heart Decompensation | Not applicable | Completed | Radboud University Medical Center | 86 | 2020-12-14 | 2023-06-15 |
| Interest of the Smartphone Application "MonCœur" in the Follow-up of Patients With Heart Failure APPLI - Heart Failure, Heart Decompensation | Not applicable | Terminated | French Cardiology Society | 125 | 2020-02-12 | 2023-12-01 |
| An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic BMS-986231, Furosemide, Placebo - Cardiac Failure, Myocardial Failure | Phase 2 | Completed | Bristol-Myers Squibb | 23 | 2019-01-17 | 2021-02-26 |
| An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function BMS-986231 - Liver Dysfunction, Liver Insufficiency | Phase 1 | Completed | Bristol-Myers Squibb | 76 | 2018-05-25 | 2020-08-27 |
| Study of the Sudden Heart Failure Participant Population in the US Non-Interventional - Heart Decompensation | Withdrawn | Bristol-Myers Squibb | 2017-08-22 | 2022-07-08 | ||
| Short-term Efficacy of Furosemide, Isosorbide Dinitrate and Their Combination in ADHF Furosemide, Isosorbide Dinitrate - Heart Decompensation | Not applicable | Withdrawn | Chinese University of Hong Kong | 2017-01-01 | 2023-03-21 | |
| Skeletal Muscles in Acute Heart Failure cardiac rehabilitation - Heart Decompensation | Unknown | Wroclaw University of Health and Sport Sciences | 30 | 2016-04-21 | 2017-04-05 | |
| Pilot Study for the Evaluation of the Safety and Performance of the RenaSense System in Hospitalized Acute Decompensated Heart Failure Patients RenaSense Stimulation, RenaSense Sham Control - Heart Decompensation, Heart Failure, Congestive | Phase 1 / Phase 2 | Unknown | Nephera Ltd. | 36 | 2015-01-01 | 2014-12-24 |
| Early-start Exercise Training in Subacute Heart Failure Aerobic exercise training, Standard physical therapy - Chronic Heart Failure, Heart Decompensation | Not applicable | Unknown | Fondazione Salvatore Maugeri | 200 | 2013-10-01 | 2014-01-31 |
| Pronostic Value of Endothelial Dysfunction in Heart Failure Heart Decompensation, Cardiac Failure | Terminated | Centre Hospitalier Universitaire de Besancon | 7 | 2012-10-01 | 2016-08-09 | |
| Big Data to Assess the Healthcare and Health Outcomes Burden of Acute Coronary Syndromes Complicated With Heart Failure Heart Failure, Acute Coronary Syndrome | Completed | Hospital Universitari de Bellvitge | 7860560 | 2012-01-01 | 2024-02-16 | |
| A Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF) Cinaciguat (BAY58-2667), Placebo - Heart Failure, Heart Decompensation | Phase 2 | Terminated | Bayer | 62 | 2010-04-01 | 2015-10-08 |
| Treating Congestive Heart Failure Using a Device to Remove Cholesterol Kaneka Liposorber - Heart Decompensation | Early Phase 1 | Completed | Patrick Moriarty, MD, FACP, FACC | 5 | 2007-07-01 | 2016-01-13 |
| A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure Nesiritide, Placebo - Heart Decompensation | Phase 3 | Completed | Scios, Inc. | 7141 | 2007-05-01 | 2013-03-08 |
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Heart Failure (29) · Cardiomyopathies (4) · Renal Insufficiency (3) · Dyspnea (2) · Dyspnea, Paroxysmal (2) · Myocardial Infarction (2) · Ventricular Dysfunction, Left (2) · Acute Coronary Syndrome (1) · Arrhythmias, Cardiac (1) · Atrial Fibrillation (1) · Atrial Remodeling (1) · Cardiac Output, Low (1) · Coitus (1) · Fibrosis (1) · Heart Block (1)
Cardiovascular Diseases (29) · Heart Diseases (29) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (6) · Respiration Disorders (5) · Respiratory Tract Diseases (5) · Signs and Symptoms, Respiratory (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Kidney Diseases (3) · Male Urogenital Diseases (3) · Pathologic Processes (3) · Urogenital Diseases (3) · Urologic Diseases (3) · Behavior (2)
Natriuretic Peptide, Brain (5) · Furosemide (2) · BAY 58-2667 (1) · Blood Specimen Collection (1) · Cardiac Rehabilitation (1) · Echocardiography (1) · Isosorbide Dinitrate (1) · NPPA protein, human (1) · Observation (1) · Simendan (1)
Scios, Inc. (6) · Bristol-Myers Squibb (3) · French Cardiology Society (2) · Asan Medical Center (1) · Bayer (1) · Centre Hospitalier Universitaire de Besancon (1) · Chinese University of Hong Kong (1) · Corteria Pharmaceuticals (1) · Daiichi Sankyo (1) · Emory University (1) · Fondazione Salvatore Maugeri (1) · Hospital Universitari de Bellvitge (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Nephera Ltd. (1) · Patrick Moriarty, MD, FACP, FACC (1)
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Alessandro Mezzani, MD (1) · Alexander Zipprich (1) · Alexandre Mebazaa, MD (1) · Biljana Pavlovic-Surjancev, MD, PhD (1) · Colin A Graham, MD (1) · Janet M Simsic, MD (1) · Marijn de Bruin, prof. dr. (1) · Pantaleo Giannuzzi, MD (1) · Patrick Moriarty, M.D. (1)
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