Heart Decompensation: Clinical Trials

2 completed, 1 terminated, 1 unknown. 4 Phase 2, 1 Phase 1.

By phase and status

Phase	Trials	Status
Phase 2	4	Completed 2, Terminated 1, Unknown 1
Phase 1	1	Unknown 1

Follow Heart Decompensation: new trials by email Literature Review of Heart Decompensation trials Research Report on Heart Decompensation

Trials (filtered) newest first · largest first

All 4 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic BMS-986231, Furosemide, Placebo - Cardiac Failure, Myocardial Failure	Phase 2	Completed	Bristol-Myers Squibb	23	2019-01-17	2021-02-26
Pilot Study for the Evaluation of the Safety and Performance of the RenaSense System in Hospitalized Acute Decompensated Heart Failure Patients RenaSense Stimulation, RenaSense Sham Control - Heart Decompensation, Heart Failure, Congestive	Phase 1 / Phase 2	Unknown	Nephera Ltd.	36	2015-01-01	2014-12-24
A Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF) Cinaciguat (BAY58-2667), Placebo - Heart Failure, Heart Decompensation	Phase 2	Terminated	Bayer	62	2010-04-01	2015-10-08
Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure Carperitide, Placebo - Heart Failure, Congestive, Heart Decompensation	Phase 2	Completed	Daiichi Sankyo	162	2004-01-01	2016-11-08

Narrower conditions

Heart Failure (4)  ·  Cardiomyopathies (1)  ·  Renal Insufficiency (1)  ·  Systolic Murmurs (1)  ·  Ventricular Dysfunction, Left (1)

Broader conditions

Cardiovascular Diseases (4)  ·  Heart Diseases (4)  ·  Female Urogenital Diseases (1)  ·  Female Urogenital Diseases and Pregnancy Complications (1)  ·  Heart Murmurs (1)  ·  Kidney Diseases (1)  ·  Male Urogenital Diseases (1)  ·  Pathological Conditions, Signs and Symptoms (1)  ·  Signs and Symptoms (1)  ·  Urogenital Diseases (1)  ·  Urologic Diseases (1)  ·  Ventricular Dysfunction (1)

Interventions

BAY 58-2667 (1)  ·  Furosemide (1)  ·  NPPA protein, human (1)

Sponsors

Bayer (1)  ·  Bristol-Myers Squibb (1)  ·  Daiichi Sankyo (1)  ·  Nephera Ltd. (1)

Countries

Canada (2)  ·  Israel (2)  ·  United Kingdom (2)  ·  United States (2)  ·  Czechia (1)  ·  Finland (1)  ·  France (1)  ·  Germany (1)  ·  Hungary (1)  ·  Ireland (1)  ·  Italy (1)  ·  Japan (1)  ·  Poland (1)  ·  South Africa (1)  ·  South Korea (1)

Top investigators

Biljana Pavlovic-Surjancev, MD, PhD (1)

Results publications

PMID 31168885

NIH funding

2009 (1), 2018 (1)