1248 completed, 362 unknown, 176 recruiting, 124 terminated. 758 Not applicable, 278 Phase 4, 241 Phase 3, 225 Phase 2, 113 Phase 1.
Follow Glaucoma: new trials by email Literature Review of Glaucoma trials Research Report on Glaucoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients brimonidine tartrate ophthalmic solution 0.025%, sterile balanced saline solution - Glaucoma, Glaucoma, Open-Angle | Phase 4 | Not yet recruiting | Tulane University | 60 | 2027-11-01 | 2026-10-13 |
| Know Your Pressures NYC Virtual Automated Navigator Intervention with Health Education, Usual Care - Glaucoma, Hypertension | Not applicable | Not yet recruiting | Columbia University | 7085 | 2027-07-01 | 2026-08-25 |
| Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial) Nicotinamide, Standard Glaucoma Therapy - Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) | Phase 2 | Not yet recruiting | University of Chicago | 96 | 2027-06-01 | 2026-10-13 |
| Glaucoma Drop Aids Part 2 Nanodropper - Glaucoma, Intraocular Pressure | Not applicable | Not yet recruiting | Boston Medical Center | 80 | 2027-01-01 | 2026-10-30 |
| VGFTe-(HD)-OD-2566: Adjunctive Aflibercept Ahmed Glaucoma Valve (AAA) Study Aflibercept Injection, Ahmed Tube Surgery - Glaucoma | Phase 2 | Not yet recruiting | University of Miami | 100 | 2026-12-01 | 2026-10-23 |
| Impact of Meditation on Reducing Stress in Glaucoma Patients: An Electronic Feasibility Study Meditation + Usual Care - Glaucoma | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 158 | 2026-11-01 | 2026-08-18 |
| PAUL® Glaucoma Implant Safety and Effectiveness Study PAUL® Glaucoma Implant - Refractory Glaucoma | Not applicable | Not yet recruiting | Clinical Research Consultants, Inc. | 65 | 2026-11-01 | 2026-10-30 |
| Baerveldt Versus Paul Study Baerveldt Glaucoma Implant, Paul Glaucoma Implant - Glaucoma | Phase 4 | Not yet recruiting | University of Sydney | 150 | 2026-10-12 | 2026-08-03 |
| A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage ASP2767, Sham ASP2767, Prophylactic Regimen A - Glaucoma | Phase 1 / Phase 2 | Recruiting | Astellas Pharma Global Development, Inc. | 156 | 2026-10-07 | 2026-10-22 |
| Switching From Preserved Glaucoma Therapy to Preservative-Free ZOLYMBUS preservative free ZOLYMBUS™ 0.01%. - Eye Drops Self-instillation, Glaucoma | Phase 4 | Not yet recruiting | Southern College of Optometry | 40 | 2026-10-05 | 2026-09-28 |
| Iopidine to Decrease Intraocular Pressure Rise After Injections Apraclonidine 1.0% ophthalmic solution - Macular Degeneration, Diabetic Retinopathy | Phase 4 | Not yet recruiting | Retina Consultants of Delmarva | 120 | 2026-10-01 | 2026-10-23 |
| Evaluation the Safety and Effectiveness of the GORE GDI in Adult Subjects With Primary Open-angle Glaucoma in Whom Previous Medical and Surgical Treatment Have Failed. GORE Glaucoma Drainage Implant - Glaucoma, Primary Open Angle | Not applicable | Not yet recruiting | Gore Ophthalmic | 70 | 2026-10-01 | 2026-10-19 |
| GlaukomAI: Clinical Validation of an AI System for Early Glaucoma Screening GlaukomAI (Sens-vue GlaukomAI) - Glaucoma | Not applicable | Not yet recruiting | Fondazione G.B. Bietti, IRCCS | 1200 | 2026-10-01 | 2026-09-04 |
| Trabeculectomy Versus MicroShunt Implantation in Glaucoma Surgery (TIGER) Preserflo MicroShunt, Trabeculectomy - Glaucoma | Not applicable | Not yet recruiting | Oslo University Hospital | 100 | 2026-10-01 | 2026-10-09 |
| Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure Glaucoma Combined Phacoemulsification and Goniotomy - Primary Open-Angle Glaucoma, Primary Angle-Closure Glaucoma | Not applicable | Not yet recruiting | Assiut University | 70 | 2026-10-01 | 2026-09-16 |
| Adaptive Optics OCT Evaluation of Rhopressa's Effects on the Retinal Ganglion Cells in Glaucoma Patients Netarsudil 0.02% Ophthalmic Solution [RHOPRESSA], Timolol Maleate 0.25% Ophthalmic Solution - Open Angle Glaucoma (OAG), Glaucoma | Phase 4 | Recruiting | Brett King | 13 | 2026-10-01 | 2026-10-28 |
| Visual Function and Exercise in Glaucoma Patients answer questionnaire - Glaucoma, Exercise | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 100 | 2026-09-30 | 2026-09-17 | |
| Ocular Surface Disease in Glaucoma Patients on Long-Term Therapy Glaucoma, Ocular Surface Disease | Not yet recruiting | Assiut University | 55 | 2026-09-26 | 2026-09-28 | |
| Comparative Study of the Tomey FT-1000, and Goldmann Applanation Tonometer (GAT) Non Contact Tonometer and Applanation Tonometer - Glaucoma | Recruiting | Tomey Corporation | 30 | 2026-09-23 | 2026-10-06 | |
| Efficacy and Safety of a Releasable Intraluminal Suture Technique to Reduce Hypotony Following Glaucoma Surgery Using the Preserflo Device Classical surgery, Intraluminal suture - Glaucoma | Not applicable | Recruiting | Hôpital Privé de la Baie | 192 | 2026-09-17 | 2026-10-02 |
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Eye Diseases (2060) · Ocular Hypertension (1499) · Lens Diseases (106) · Cardiovascular Diseases (98) · Vascular Diseases (97) · Nervous System Diseases (83) · Retinal Diseases (81) · Optic Nerve Diseases (71) · Pathological Conditions, Signs and Symptoms (67) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (63) · Uveal Diseases (59) · Endocrine System Diseases (55) · Retinal Degeneration (55) · Behavior (49)
Latanoprost (164) · Timolol (128) · Travoprost (104) · Ophthalmic Solutions (84) · Bimatoprost (79) · Trabeculectomy (75) · Brimonidine Tartrate (59) · brinzolamide (55) · dorzolamide (40) · dorzolamide-timolol combination (39) · Phacoemulsification (37) · Cataract Extraction (32) · Mitomycin (30) · Duotrav (24) · tafluprost (22)
Alcon Research (135) · Allergan (82) · Glaukos Corporation (48) · Wills Eye (48) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (27) · Aerie Pharmaceuticals (25) · Medical University of Vienna (24) · Sensimed AG (22) · Sun Yat-sen University (22) · Universitaire Ziekenhuizen KU Leuven (20) · University of Zurich (20) · Zhongshan Ophthalmic Center, Sun Yat-sen University (18) · Aristotle University Of Thessaloniki (17) · Duke University (17) · Stanford University (16)
United States (721) · Canada (112) · China (112) · Germany (101) · France (77) · Egypt (75) · Italy (74) · United Kingdom (74) · Spain (69) · Switzerland (61) · South Korea (54) · Austria (53) · Belgium (45) · Israel (38) · Singapore (36)
Ingeborg Stalmans, MD, PhD (9) · Anastasios G Konstas, MD, PhD (7) · George L Spaeth, MD (7) · Robert Ritch, MD (7) · Theresa Heah, MD (7) · William C. Stewart, MD (7) · Zubair Hussain, PhD (7) · Gong Je Seong, MD, PhD (6) · Jeffrey L Goldberg, MD, PhD (6)
PMID 35943114, PMID 36912740, PMID 10937547, PMID 24974815, PMID 17122118, PMID 12049574, PMID 19427617, PMID 24210765, PMID 35643967, PMID 40408035, PMID 11772581, PMID 12365904, PMID 16249960, PMID 16488940, PMID 17159450, PMID 19277230, PMID 19476406, PMID 22427577, PMID 22607109, PMID 23557744, PMID 23746612, PMID 25336577, PMID 25358735, PMID 26199618, PMID 26604914, PMID 26674779, PMID 26891880, PMID 27117781, PMID 27769587, PMID 27857759, PMID 27904503, PMID 28551166, PMID 29194198, PMID 29267575, PMID 29477688, PMID 29613978, PMID 31294768, PMID 31727428, PMID 32166538, PMID 32277009, PMID 34003939, PMID 34433548, PMID 34707360, PMID 35076329, PMID 36122660, PMID 36378864, PMID 37010901, PMID 37793935, PMID 38985408, PMID 39240530
2014 (5), 2018 (5), 2008 (4), 2015 (4), 2019 (4), 2009 (3), 2023 (3), 2016 (2), P30AG022838 (2), R01EY013178 (2), R01EY022124 (2), R01EY023285 (2), U01DP006820 (2), UL1TR001082 (2), 2017 (1)