19 completed, 13 unknown, 2 not yet recruiting, 1 enrolling by invitation. 21 Not applicable, 3 Phase 1, 2 Early Phase 1, 2 Phase 2, 1 Phase 3.
Follow Hydrophthalmos: new trials by email Literature Review of Hydrophthalmos trials Research Report on Hydrophthalmos
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Goniotomy in Primary Congenital Glaucoma Primary Congenital Glaucoma, Goniotomy | Not yet recruiting | Sun Yat-sen University | 120 | 2026-05-01 | 2026-04-24 | |
| Study Aim to Compare the Effect of Different Technique of Airway Managment During Anaesthesia on the Haemodynamics and Intraocular Pressure. Patients Were Divided Into Three Groups of 25 Patients Each. (Group A); Patients Who Were Subjected to LMA Insertion (Group B ). laryngeal mask insertion, I gel mask insertion, Endotracheal tube insertion - Congenital Glaucoma | Not applicable | Not yet recruiting | Sohag University | 75 | 2026-03-10 | 2026-03-31 |
| Electron Microscopic Examination of Iris Tissue in Buphthalmos Combined trabeculotomy trabeculectomy with mitomycin C - Iris Diseases | Not applicable | Completed | Assiut University | 20 | 2024-06-01 | 2025-06-24 |
| Assessing Combined Bevacizumab-Mitomycin C Use During Ahmed Valve Revision in Recurrent Pediatric Glaucoma AGV plate, bevacizumab injection - Pediatric Glaucoma | Early Phase 1 | Completed | Benha University | 50 | 2024-02-09 | 2025-05-21 |
| Combined Nasal Goniotomy-Temporal Trabeculotomy Versus Temporal Trabeculotomy for Management of Primary Congenital Glaucoma combined Nasal goniotomy-Temporal trabeculotomy, Temporal trabeculotomy - Primary Congenital Glaucoma | Not applicable | Completed | Zagazig University | 21 | 2024-02-01 | 2026-09-21 |
| Combined Phacoaspiration and Angle Surgery Versus Phacoaspiration in Pediatric Cataract Group A :combined phacoaspiration and angle surgery, Group B : phacoaspiration only - Pediatric Glaucoma | Not applicable | Unknown | Mansoura University | 30 | 2022-05-30 | 2022-09-08 |
| Non-penetrating Deep Sclerectomy Versus Trabeculotomy- Trabeculectomy Operation in Treatment of Primary Congenital Glaucoma non-penetrating deep sclerectomy, primary combined trabeculotomy-trabeculectomy - Congenital Glaucoma | Not applicable | Unknown | Al-Azhar University | 40 | 2022-02-01 | 2024-01-03 |
| Evaluation of Primary Congenital Glaucoma at Asyut University Hospital Combined trabeculotomy-trabeculectomy with mitomycin C - Primary Congenital Glaucoma | Not applicable | Unknown | Omar Abdelkarem Hasan | 30 | 2022-02-01 | 2022-01-24 |
| Subscleral Trabeculectomy With Inverted T-Shaped Deep Sclerectomy for Primary Congenital Glaucoma Subscleral Trabeculectomy Combined With Inverted T-Shaped Deep Sclerectomy - Primary Congenital Glaucoma, Pediatric Glaucoma | Not applicable | Completed | Benha University | 34 | 2022-01-01 | 2026-07-14 |
| Kahook Dual Blade Ab-interno Trabeculotomy Versus ab Externo Viscotrabeculotomy in Primary Congenital Glaucoma ab externo viscotrabeculotomy, The Kahook dual blade® (KDB) assisted ab-interno trabeculotomy - Glaucoma, Congenital Glaucoma | Not applicable | Unknown | Mansoura University | 60 | 2021-11-01 | 2021-11-10 |
| A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101 QLS-101ophthalmic solution 1%, QLS-101ophthalmic solution 2% - Sturge-Weber Syndrome (SWS), Glaucoma | Phase 2 | Completed | Qlaris Bio, Inc. | 3 | 2021-10-19 | 2025-01-20 |
| Viscotrabeculotomy in Pediatric Glaucoma Following Cataract Surgery single-site rigid probe viscotrabeculotomy (VT), two-site rigid probe viscotrabeculotomy (VT) - Glaucoma Congenital | Not applicable | Unknown | Mansoura University | 20 | 2021-09-01 | 2021-08-18 |
| Surgery for Primary Congenital Glaucoma in Neonates viscotrabeculotomy (VT), visco-circumferential-suture-trabeculotomy (VCST) ., combined VT-Trabeculectomy with MMC (VT-Trab). - Primary Congenital Glaucoma | Not applicable | Unknown | Mansoura University | 60 | 2021-03-01 | 2021-01-14 |
| Long Term Evaluation of Primary Congenital Glaucoma Management in Sohag University Hospital Primary congenital glaucoma evaluation - Primary Congenital Glaucoma | Unknown | Sohag University | 150 | 2021-01-01 | 2022-02-09 | |
| Cognitive Behavioral Nursing Model Cognitive Behavioral Nursing Model - Cognitive Behavioral Nursing, Congenital Glaucoma | Not applicable | Completed | Taiyuan Central Hospital of Shanxi Medical University | 153 | 2021-01-01 | 2024-04-24 |
| Iris Tissue in Primary Congenital Glaucoma Combined trabeculotomy-trabeculectomy with mitomycin c - Primary Congenital Glaucoma | Not applicable | Unknown | Assiut University | 15 | 2020-12-01 | 2020-10-22 |
| Comparison of Surgical Treatment Options for Primary Congenital and Developmental Glaucomas Santen PRESERFLO MicroShunt, Trabeculectomy - Primary Congenital Glaucoma, Developmental Glaucoma | Not applicable | Withdrawn | University of Zurich | 2020-12-01 | 2023-06-05 | |
| Establishment of an Anaesthetic Protocol for Examinations for Children With Glaucoma or Suspected Glaucoma Anesthesia, Intraocular Pressure | Completed | Johannes Gutenberg University Mainz | 120 | 2019-06-01 | 2026-01-02 | |
| INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register Glaucoma Open-Angle, Glaucoma Eye | Enrolling by invitation | Dr. Kaweh Mansouri | 30000 | 2019-01-15 | 2022-05-05 | |
| Optical Coherence Tomography of the Irido-Corneal Angle Before and After Goniotomy and Trabeculotomy in Primary Congenital Glaucoma Optical coherence tomography - Optical Coherence Tomography, Anterior Chamber Angle | Not applicable | Completed | Cairo University | 32 | 2018-10-01 | 2025-06-10 |
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Glaucoma (9) · Ocular Hypertension (3) · Aniridia (1) · Burns, Chemical (1) · Cataract (1) · Coloboma (1) · Exfoliation Syndrome (1) · Eye Diseases (1) · Glaucoma, Angle-Closure (1) · Glaucoma, Neovascular (1) · Glaucoma, Open-Angle (1) · Graft vs Host Disease (1) · Iris Diseases (1) · Nystagmus, Pathologic (1)
Congenital Abnormalities (37) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (37) · Eye Abnormalities (37) · Infant, Newborn, Diseases (37) · Eye Diseases (36) · Glaucoma, Open-Angle (36) · Ocular Hypertension (34) · Glaucoma (28) · Eye Diseases, Hereditary (3) · Uveal Diseases (3) · Iris Diseases (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Nervous System Diseases (2) · Angiomatosis (1)
Trabeculectomy (4) · Mitomycin (3) · Bevacizumab (1) · Intubation, Intratracheal (1) · Latanoprost (1) · Ophthalmic Solutions (1) · Timolol (1) · Tomography, Optical Coherence (1) · Travoprost (1) · collagen-glycosaminoglycan copolymer (1) · dorzolamide (1)
Mansoura University (5) · Alcon Research (2) · Assiut University (2) · Benha University (2) · Sohag University (2) · Al-Azhar University (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Cairo University (1) · Carmel Medical Center (1) · Dr. Kaweh Mansouri (1) · Federal University of São Paulo (1) · Implandata Ophthalmic Products GmbH (1) · Johannes Gutenberg University Mainz (1) · King Saud University (1) · L.V. Prasad Eye Institute (1)
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Ahmed S Elwehidy, DM (1) · B. Wirostko, M.D. (1) · Camila F Netto, MD (1) · Carlos Rodriguez-Galindo, MD (1) · Chang Won Kee, M.D. (1) · Luciano Quaranta, MD (1) · Nigar Makhmudova (1) · Orna Geyer, Professor (1) · Saleh A. Al-Obeidan, MD (1) · Subha Venkataraman (1) · Subha Venkataraman, Clinical Project Lead (1) · Thomas Neuhann, Prof. MD (1)
PMID 11146740, PMID 21168818, PMID 26315044, PMID 26766400, PMID 27312975, PMID 28957960, PMID 32890108, PMID 34610927
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