12 completed, 11 recruiting, 4 not yet recruiting, 3 terminated. 12 Not applicable, 8 Phase 2, 3 Phase 1, 2 Phase 3, 1 Phase 4.
Follow Gastrointestinal Cancers: new trials by email Literature Review of Gastrointestinal Cancers trials Research Report on Gastrointestinal Cancers
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Multicenter Prospective Observational Cohort Study for Digestive Tract Tumor Screening Using Multi-Target Blood and Fecal Biomarkers Gastrointestinal Cancers | Recruiting | Xijing Hospital | 5000 | 2026-08-10 | 2026-08-18 | |
| Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma BHB810 - Gastric Cancer, Gastric Adenocarcinoma | Phase 1 / Phase 2 | Recruiting | BigHat Biosciences, Inc. | 164 | 2026-07-16 | 2026-10-20 |
| Safety and Efficacy of NOM and OPFS Versus RO for dMMR/MSI-H or POLE-Mutated Gastrointestinal Cancers NOM/OPFS - Gastrointestinal Cancers, Gastrointestinal Cancers - Stomach | Not yet recruiting | Peking University Cancer Hospital & Institute | 22 | 2026-07-15 | 2026-06-11 | |
| Clinical Evaluation of AI Decision Support for Early Rehabilitation After Surgery DESIRE: AI-Based Clinical Decision Support for Postoperative Rehabilitation Planning - Oncologic Surgery, Gastrointestinal Cancers | Not applicable | Not yet recruiting | Erasmus Medical Center | 103 | 2026-06-01 | 2026-02-12 |
| Study to Assess the Efficacy and Safety of Rina-S in Participants With Advanced Gastrointestinal (GI) Cancers Rina-S - Gastrointestinal Cancers | Phase 2 | Recruiting | Genmab | 160 | 2026-05-11 | 2026-10-06 |
| A Randomized, Double-blind, Placebo-controlled, Prospective, Multi-center Trial Evaluating the Improvement of Nutritional Status and Sarcopenia With Silkworm Pupa Tablets in Patients With Malignancies Silkworm pupa tablets, Placebo - Nutritional Deficiency, Gastrointestinal Cancers | Phase 3 | Not yet recruiting | First Affiliated Hospital of Zhejiang University | 480 | 2026-04-01 | 2026-04-28 |
| Clinical Investigator-Initiated Trial (IIT) of PD-L1-Targeted Radionuclide Probes 18F-FDG, [18F]F-PDL1-3 - Lung Cancer (NSCLC), Cervical Squamous Cell Cancer | Phase 2 | Recruiting | Peking University Cancer Hospital & Institute | 50 | 2026-02-01 | 2026-09-29 |
| A Real-world Study of Adebrelimab-based Combination Regimens in the Treatment of Advanced Solid Tumors Adebrelimab - Non-Small Cell Lung Cancer, Small Cell Lung Cancer | Not yet recruiting | Tianjin First Central Hospital | 300 | 2025-09-15 | 2025-09-15 | |
| Impact of Glycemic Variability on People With Gastrointestinal Cancer and Diabetes After Surgery CARE program, Usual Care - Diabetes Melletus, Gastrointestinal Cancers | Not applicable | Active not recruiting | National Taiwan University Hospital | 260 | 2025-09-08 | 2025-09-18 |
| Predictive Value of Preoperative Rectus and Diaphragm Muscle Thickness for Postoperative Complications in Gastrointestinal Cancer Surgery Ultrasonography (Rectus and diaphragma muscle thickness measurement) - Gastrointestinal Cancers, Complication | Completed | Ankara Oncology Research and Training Hospital | 129 | 2025-09-01 | 2026-05-13 | |
| Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer. CYTALUX™ (pafolacianine) injection preoperatively - Esophageal Cancer, Gastrointestinal Cancers | Phase 2 | Recruiting | John Waters | 50 | 2025-08-19 | 2026-06-05 |
| Evaluating a Bidirectional Priming Intervention for Goals-of-care Communication in Oncology Priming Survey - Lung Cancers, Gastrointestinal Cancers | Not applicable | Completed | Abramson Cancer Center at Penn Medicine | 40 | 2025-07-21 | 2026-03-04 |
| Prophylactic or Preemptive Entecavir in Patients With Gastrointestinal Cancer Who Are Inactive Hepatitis B Carriers Entecavir - Gastrointestinal Cancers | Phase 3 | Recruiting | Sun Yat-sen University | 136 | 2025-05-15 | 2025-05-11 |
| FRAIL and FiND for Chemotherapy Toxicity in GI Cancer No Intervention - Gastrointestinal Cancers, Frailty at Older Adults | Completed | Ankara Etlik City Hospital | 122 | 2025-05-02 | 2026-10-19 | |
| Feasibility Study of CBCT for IGRT in Cancer Patients Comparison of HyperSight CBCT imaging to conventional CBCT imaging. - Head and Neck Cancers, Breast Cancer | Not applicable | Recruiting | Varian, a Siemens Healthineers Company | 50 | 2025-02-19 | 2026-03-13 |
| Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery Local Anesthesia, Laparoscopic Transversus Abdominis Plane block - Oncologic Surgery, Cancer | Not applicable | Recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 48 | 2025-02-05 | 2025-09-18 |
| Electroacupuncture Combined With Self-administered Acupressure for the Prevention of Capecitabine-Associated Hand-Foot Syndrome True electroacupuncture + True self-administered acupressure, Doctor-prescribed treatment, Sham electroacupuncture + Sham self-administered acupressure - Capecitabine, Hand-foot Syndrome | Not applicable | Recruiting | Affiliated Hospital of Qinghai University | 220 | 2024-10-08 | 2024-12-12 |
| Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors Implementation of social determinants of health screening and referral - Cancer, Cancer Survivors | Not applicable | Recruiting | Barbara Ann Karmanos Cancer Institute | 120 | 2024-09-03 | 2025-08-26 |
| TENS and Compression for Established Oxaliplatin-Induced Peripheral Neuropathy TENS, Compression Garments, Sequential TENS Plus Compression - CIPN - Chemotherapy-Induced Peripheral Neuropathy, Gastrointestinal Cancers | Not applicable | Completed | Cumhuriyet University | 140 | 2024-08-02 | 2026-09-09 |
| Electronic Patient Reported Outcomes in Patients With Gastrointestinal Cancers Electronic Patient Reported Outcomes platform, Health Related Quality of Life Surveys - Gastrointestinal Cancers, Gastrointestinal Cancer Metastatic | Not applicable | Withdrawn | University of California, San Francisco | 2024-06-15 | 2024-05-08 |
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Gastrointestinal Neoplasms (36) · Breast Neoplasms (6) · Colorectal Neoplasms (6) · Lung Neoplasms (5) · Neoplasms (5) · Melanoma (4) · Stomach Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3) · Head and Neck Neoplasms (3) · Pancreatic Neoplasms (3) · Biliary Tract Neoplasms (2) · Brain Neoplasms (2) · Esophageal Neoplasms (2) · Frailty (2) · Liver Neoplasms (2)
Digestive System Diseases (36) · Digestive System Neoplasms (36) · Gastrointestinal Diseases (36) · Neoplasms by Site (36) · Neoplasms (31) · Neoplasms by Histologic Type (9) · Respiratory Tract Diseases (8) · Colonic Diseases (7) · Intestinal Diseases (7) · Intestinal Neoplasms (7) · Lung Diseases (7) · Pathological Conditions, Signs and Symptoms (7) · Respiratory Tract Neoplasms (7) · Thoracic Neoplasms (7) · Breast Diseases (6)
Anesthesia, Local (1) · Bevacizumab (1) · Erlotinib Hydrochloride (1) · Everolimus (1) · Fluorodeoxyglucose F18 (1) · Gastrectomy (1) · Gefitinib (1) · Hyperthermic Intraperitoneal Chemotherapy (1) · Imatinib Mesylate (1) · Ketamine (1) · Pafolacianine (1) · Proctectomy (1) · Psychotherapy (1) · Quality of Life (1) · Radiosurgery (1)
Ankara Etlik City Hospital (2) · Peking University Cancer Hospital & Institute (2) · Sun Yat-sen University (2) · AIO-Studien-gGmbH (1) · Abramson Cancer Center at Penn Medicine (1) · Affiliated Hospital of Qinghai University (1) · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) (1) · Ankara Oncology Research and Training Hospital (1) · Barbara Ann Karmanos Cancer Institute (1) · Bay Area Gynecology Oncology (1) · BigHat Biosciences, Inc. (1) · Brian Anderson, MD (1) · Brigette Ma (1) · Cumhuriyet University (1) · Dana-Farber Cancer Institute (1)
United States (16) · China (6) · Turkey (Türkiye) (4) · Netherlands (2) · Australia (1) · France (1) · Germany (1) · Hong Kong (1) · Japan (1) · South Korea (1) · Taiwan (1) · United Kingdom (1)
Galip Can Uyar, MD (2) · Alix G Sleight, PhD, OTD, MPH, OTR/L (1) · Anne E Belcher, PhD (1) · Brian T Anderson, MD (1) · Casey Allen, MD (1) · Edward Giovannucci, MD, ScD (1) · Gary G Bennett, PhD (1) · Hsuan-Ju Kuo, PhD (1) · Hua Zhu (1) · James B Yu, MD (1) · James Lilja, MD (1) · John Waters, M.D. (1) · Karin Jordan, Dr. med. (1) · Neeta Venepalli, MD (1) · Steven A Rosenberg, M.D. (1)
PMID 23487599, PMID 24327720, PMID 24368437, PMID 24657333, PMID 24974387, PMID 25447852, PMID 25514302, PMID 26858840
2025 (1), K01HD110719 (1)