328 completed, 160 recruiting, 141 unknown, 68 terminated. 401 Phase 2, 192 Phase 1, 114 Not applicable, 72 Phase 3, 17 Phase 4.
Follow Biliary Tract Neoplasms: new trials by email Literature Review of Biliary Tract Neoplasms trials Research Report on Biliary Tract Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multicenter Phase 2 Study of Envafolimab in Biliary Tract Cancers Envafolimab plus Gemcitabine&Cisplatin, Gemcitabine&Cisplatin - Biliary Tract Neoplasms | Phase 2 | Not yet recruiting | 3D Medicines (Sichuan) Co., Ltd. | 126 | 2027-06-01 | 2026-03-25 |
| Investigating Precision Medicine in the Adjuvant Setting in Biliary Tract Cancer Futibatinib, Ivosidenib + Capecitabine, Zanidatamab + Capecitabine - Biliary Tract Cancer (BTC) | Phase 3 | Not yet recruiting | UNICANCER | 990 | 2027-01-02 | 2026-08-04 |
| TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE) Music-assisted relaxation and imagery (MARI) - Surgery, Stomach Cancer | Not applicable | Not yet recruiting | Case Comprehensive Cancer Center | 20 | 2027-01-01 | 2026-08-05 |
| Zanidatamab Combined With Liposomal Irinotecan and Capecitabine for Second-line Treatment of HER2-positive Unresectable Biliary Tract Tumors Zanidatamab - Biliary Tract Cancer | Phase 2 | Not yet recruiting | Anhui Provincial Hospital | 15 | 2026-11-30 | 2026-10-01 |
| Tucatinib Continuation Study tucatinib - HER2-positive Breast Cancer, Cervical Cancer | Phase 4 | Not yet recruiting | Pfizer | 175 | 2026-11-06 | 2026-08-28 |
| Phase 2 Study of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract Cancer Daraxonrasib - Biliary Tract Cancers, Intrahepatic Cholangiocarcinoma (Icc) | Phase 2 | Not yet recruiting | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 55 | 2026-11-01 | 2026-08-28 |
| Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma Biospecimen Collection, Cisplatin, Computed Tomography - Locally Advanced Ampulla of Vater Carcinoma, Locally Advanced Biliary Tract Carcinoma | Phase 2 | Recruiting | Ohio State University Comprehensive Cancer Center | 29 | 2026-11-01 | 2026-09-10 |
| IKS04 Regimen in Advanced Solid Tumors That Express CA242 IKS04 antibody drug conjugate ADC + Isumab04 monoclonal antibody - Colorectal Cancer, Gastro Esophageal Junctional Cancer | Phase 1 | Not yet recruiting | Iksuda Therapeutics Ltd. | 120 | 2026-11-01 | 2026-07-31 |
| SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET [225Ac]Ac-FL-261 - Solid Tumor, NSCLC | Phase 1 / Phase 2 | Recruiting | Full-Life Technologies UK Limited | 208 | 2026-10-01 | 2026-10-16 |
| Study on Sequential Cryoablation, Relaforp Alpha, and Chemotherapy for Bile Duct Tumors PD-1 and chemotherapy, cryoablation - Biliary Tract Cancer (BTC) | Phase 2 | Recruiting | Tianjin Medical University Cancer Institute and Hospital | 30 | 2026-10-01 | 2026-07-24 |
| Scheduled Meditation for Improving Postoperative Outcomes in Patients Undergoing Pancreatectomy Actigraphy, Online Mindfulness Meditation, Smartphone Application-based Intervention - Hepatocellular Carcinoma, Pancreas Cancer | Not applicable | Not yet recruiting | City of Hope Medical Center | 70 | 2026-10-01 | 2026-08-20 |
| A Phase II Study of Ivonescimab in Combination With GEMOX as Neoadjuvant and Conversion Therapy for Biliary Tract Cancer Ivonescimab, GEMOX Regimen - Biliary Tract Cancer (BTC) | Phase 2 | Recruiting | Haitao Zhao, MD | 87 | 2026-10-01 | 2026-10-02 |
| A Prospective Study of Sacituzumab Tirumotecan Plus Pembrolizumab for Advanced Biliary Tract Cancer Sacituzumab Tirumotecan (SKB264), Pembrolizumab - Biliary Tract Cancer (BTC) | Phase 2 | Recruiting | Haitao Zhao, MD | 38 | 2026-10-01 | 2026-10-05 |
| Bile ctDNA Genomic Profiling and Concordance With Tumor Tissue in Biliary Tract Cancer Bile Sampling for ctDNA Analysis - Biliary Tract Cancer (BTC) | Not yet recruiting | CHA University | 100 | 2026-10-01 | 2026-10-13 | |
| EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope Endoscopic ultrasound examination - Pancreatic Disease, Pancreatic Cancer | Not applicable | Recruiting | Orlando Health, Inc. | 140 | 2026-10-01 | 2026-10-20 |
| Single-arm, Multicenter, Open-label Phase II Study of Vedotin for Injection in Second-line or Later Treatment of Advanced Biliary Tract Cancer MRG003 (Becotatug Vedotin) - Biliary Tract Neoplasms | Phase 2 | Enrolling by invitation | Jiangmen Central Hospital | 30 | 2026-09-22 | 2026-10-22 |
| Cryoablation Combined With QL1706 (Iparomlimab/Tuvonralimab) Plus Lenvatinib in Patients With Advanced Biliary Tract Cancer. QL1706 (Iparomlimab/Tuvonralimab), Lenvatinib, Cryoablation - Biliary Tract Cancer (BTC) | Phase 2 | Not yet recruiting | Fudan University | 180 | 2026-09-20 | 2026-09-21 |
| Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality histopathology of gall bladder - Gall Bladder Carcinoma | Recruiting | Sohag University | 100 | 2026-09-20 | 2026-10-21 | |
| A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous ABBV-253 Moves Through the Body in Adult Participants With Advanced Solid Tumors ABBV-253 - Advanced Solid Tumors, Non-Small Cell Lung Cancer | Phase 1 | Recruiting | AbbVie | 130 | 2026-09-14 | 2026-10-16 |
| Suprapapillary Versus Transpapillary Plastic Stents for Unresectable Malignant Hilar Biliary Obstruction Suprapapillary plastic stent placement, Transpapillary plastic stent placement - Biliary Tract Neoplasms, Biliary Drainage | Not applicable | Not yet recruiting | National Taiwan University Hospital | 70 | 2026-09-01 | 2026-09-10 |
Showing 20 of 848. Sign in to see all of them.
Gallbladder Neoplasms (295) · Bile Duct Neoplasms (251) · Pancreatic Neoplasms (227) · Cholangiocarcinoma (209) · Stomach Neoplasms (143) · Carcinoma, Hepatocellular (104) · Colorectal Neoplasms (99) · Liver Neoplasms (91) · Esophageal Neoplasms (83) · Neoplasms (73) · Carcinoma, Non-Small-Cell Lung (72) · Colonic Neoplasms (72) · Breast Neoplasms (64) · Endometrial Neoplasms (56)
Neoplasms by Site (847) · Digestive System Diseases (845) · Digestive System Neoplasms (844) · Biliary Tract Diseases (842) · Neoplasms (775) · Neoplasms by Histologic Type (359) · Neoplasms, Glandular and Epithelial (343) · Carcinoma (321) · Adenocarcinoma (302) · Gallbladder Diseases (296) · Endocrine System Diseases (258) · Endocrine Gland Neoplasms (257) · Bile Duct Diseases (253) · Gastrointestinal Diseases (231)
Gemcitabine (164) · Cisplatin (112) · Capecitabine (67) · Oxaliplatin (61) · Fluorouracil (50) · Leucovorin (40) · durvalumab (39) · pembrolizumab (39) · Irinotecan (26) · Bevacizumab (22) · 130-nm albumin-bound paclitaxel (21) · S 1 (combination) (21) · lenvatinib (18) · Albumin-Bound Paclitaxel (17) · Nivolumab (16)
National Cancer Institute (NCI) (39) · AstraZeneca (19) · Peking Union Medical College Hospital (16) · Seoul National University Hospital (12) · Samsung Medical Center (11) · Kansai Hepatobiliary Oncology Group (10) · Massachusetts General Hospital (9) · Shanghai Zhongshan Hospital (9) · Tianjin Medical University Cancer Institute and Hospital (9) · Fudan University (8) · Memorial Sloan Kettering Cancer Center (8) · Asan Medical Center (7) · Mayo Clinic (7) · RenJi Hospital (7) · Yonsei University (7)
United States (323) · China (202) · South Korea (120) · Japan (64) · Germany (63) · France (61) · United Kingdom (57) · Spain (55) · Italy (45) · Australia (43) · Canada (43) · Taiwan (41) · Belgium (26) · India (20) · Denmark (18)
Michel Kahaleh, MD (7) · Tim F Greten, M.D. (5) · Hiroaki Nagano, MD, PhD (4) · Tanios Bekaii-Saab (4) · Vaibhav Sahai, MBBS, MS (4) · Anthony El-Khoueiry (3) · Do-Youn Oh, MD, PhD (3) · Hong Jae Chon, MD. PhD (3) · Joan B Gornals, PhD (3) · Jonathan M Hernandez, M.D. (3) · Julien Edeline, MD (3)
PMID 20375404, PMID 37121331, PMID 33198671, PMID 37069476, PMID 38661512, PMID 24146220, PMID 25477010, PMID 26179201, PMID 28818953, PMID 29433850, PMID 29954008, PMID 29961772, PMID 30420614, PMID 30642373, PMID 30998813, PMID 32461347, PMID 32707155, PMID 33798493, PMID 34508767, PMID 34515993, PMID 34748675, PMID 37075781, PMID 37934000, PMID 38319896, PMID 40812353, PMID 41887529, PMID 42176183, PMID 10548868, PMID 10960937, PMID 11251976, PMID 11261621, PMID 11494194, PMID 11574279, PMID 12196376, PMID 12393999, PMID 12455783, PMID 12794246, PMID 12850683, PMID 14525967, PMID 15129896, PMID 15558814, PMID 15646530, PMID 16515225, PMID 16682732, PMID 16849762, PMID 16875082, PMID 17707751, PMID 18006327, PMID 18470481, PMID 18669454
2023 (17), 2015 (7), 2025 (5), P30CA015083 (5), 2018 (4), P30CA033572 (4), U10CA032102 (4), 2016 (3), 2017 (3), 2019 (3), N01CM00070 (3), N01CM62201 (3), P30CA068485 (3), U10CA180888 (3), N01CM17104 (2)